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MUCHOS GRITOS DE SU CUERPO P ARA AGUA F. Batmanghelidj, M. D. RENUNCIA La información recomendacione! !o"re el con!#mo de ag#a !e $re!enta en e!te li"ro !e "a!an en entrenamiento, $er!onal e%$eriencia, m# e%ten!a in&e!tigación, otra! $#"licacione! del a#tor !o"re el tema del meta"oli!mo del ag#a de la c#er$o. El a#tor de e!te li"ro no otor ga con!ej o! m'dico! ni $r e!cri"e el #!o o la !#$r e!ión de c#al (#ier medicamento! como #na forma de tratamiento !in el con!ejo de #n m'dico de ca"ecera, a !ea directa o indirectamente. La intención del a#tor, "a!ada en lo! conocimiento! m)! reciente! de la micro*anatom+a !iolog+ a molec#lar, e! !ólo #na oferta información !o"re la im$ortancia del ag#a $ara el "iene!tar, $ara a#dar a informar al $-"lico de lo! ef ecto! $erj #diciale! de la de!hidratación crónica al c#er$o*de!de la infancia ha!ta la &eje. E!te li"ro no e!t) $en!ado como #n reem$l a o $ara el !onido con!ej o m'dico de #n m'dico. /or el contrario, el intercam"io de la información contenida en e!te li"ro con la m'dico tratante e! altamente de!ea"le. A$licación de la información recomendacione! de!crita! en e!te doc#mento !on realiado $or c#enta rie!go de la $er!ona. La a$ro"ación de la información de"e e!tar en e! tr icto c#m$limiento de la! in!tr#ccione! dada! en el $re!ente doc#mento. /er!ona! m# enferma! con antecedente! de enfermedade! gr a&e! "aj o !#$ er&i!ión $r of e!ional, e! $ecialmente a(#ello! con enfermedad renal gra&e, no !e de"e hacer #!o de la información contenida en e!te doc#mento !in la !#$er&i!ión de !# m'dico tratante. 0e hacen toda! la! recomendacione! lo! $rocedimiento! contenido! en e!te doc#mento !in garant+a $or $arte del a#tor o el editor, !#! agente! o em$leado!. El a#tor el editor declinan toda re!$on!a"ilidad en cone%ión con el #!o de la información $re!entada en e!te doc#mento. C1N2ENID10 /refacio....................................................................................................... ..........33.......... %i Introd#cción4 No trate la !ed con Medicamento! ..................................................................................... 5 Ca$+t#lo 5 6/or (#' 7la medicina7 no c#ra la enfermedad de .............................................................. 8

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Page 1: Muchos Gritos de Su Cuerpo Para Agua

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MUCHOS GRITOS DE SU CUERPO PARA AGUAF. Batmanghelidj, M. D.

RENUNCIA

La información recomendacione! !o"re el con!#mo de ag#a !e$re!enta en e!te li"ro !e "a!an en entrenamiento, $er!onal e%$eriencia,m# e%ten!a in&e!tigación, otra! $#"licacione! del a#tor !o"re el temadel meta"oli!mo del ag#a de la c#er$o. El a#tor de e!te li"ro no otorgacon!ejo! m'dico! ni $re!cri"e el #!o o la !#$re!ión de c#al(#iermedicamento! como #na forma de tratamiento !in el con!ejo de #nm'dico de ca"ecera, a !ea directa o indirectamente. La intención dela#tor, "a!ada en lo! conocimiento! m)! reciente! de la micro*anatom+a

!iolog+a molec#lar, e! !ólo #na oferta información !o"re laim$ortancia del ag#a $ara el "iene!tar, $ara a#dar a informar al$-"lico de lo! efecto! $erj#diciale! de la de!hidratación crónica alc#er$o*de!de la infancia ha!ta la &eje. E!te li"ro no e!t) $en!ado como#n reem$lao $ara el !onido con!ejo m'dico de #n m'dico. /or elcontrario, el intercam"io de la información contenida en e!te li"ro con lam'dico tratante e! altamente de!ea"le. A$licación de la información recomendacione! de!crita! en e!te doc#mento !on realiado $or c#enta rie!go de la $er!ona. La a$ro"ación de la información de"e e!tar ene!tricto c#m$limiento de la! in!tr#ccione! dada! en el $re!entedoc#mento. /er!ona! m# enferma! con antecedente! de enfermedade!

gra&e! "ajo !#$er&i!ión $rofe!ional, e!$ecialmente a(#ello! conenfermedad renal gra&e, no !e de"e hacer #!o de la informacióncontenida en e!te doc#mento !in la !#$er&i!ión de !# m'dico tratante.

0e hacen toda! la! recomendacione! lo! $rocedimiento! contenido! ene!te doc#mento !in garant+a $or $arte del a#tor o el editor, !#!agente! o em$leado!. El a#tor el editor declinan toda re!$on!a"ilidaden cone%ión con el #!o de la información $re!entada en e!te doc#mento.

C1N2ENID10

/refacio.................................................................................................................33.......... %iIntrod#cción4No trate la !ed conMedicamento! ..................................................................................... 5Ca$+t#lo 56/or (#' 7la medicina7 no c#ra la enfermedadde .............................................................. 8

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Lo! f#ndamento! ...33.........................................................................................33........... 9

El $aradigma (#e ha (#ecam"iar ...................................................................................... :La F#ente de Error enMedicina ........................................................................................... :Ca$+t#lo ;El n#e&o$aradigma .............................................................................................33......... 58Reg#lación de Ag#a en la! diferente! eta$a! de la&ida ..................................................... 59De"e !er entendido

com$letamente ................................................................................. 5<El ag#a tiene otra! $ro$iedade!im$ortante! .................................................................... 5:Ca$+t#lo 8Dolordi!$'$tico! .........................................................................................................3.3 ;9Coliti!Dolor ..............................................................................................................33.... 8=Fal!o a$endiciti!

Dolor .......................................................................................................89hernia dehiato ....................................................................... .....................................3.3 89Ca$+t#lo =Artriti! re#matoideDolor ................................................................................................... =5Dolor de e!$alda"aja ...................................................................................................33=:

Dolor dec#ello ...........................................................................................................3..3. 9>El dolorangino!o ........................................................................................................33.. 95

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Dolore! deca"ea .....................................................................................................

33.... 95ca$+t#lo!El e!tr'! lade$re!ión ........................................................................................33......... 99El Inicialmente 0ilent Com$en!ación mecani!mo! a!ociado! conde!hidratación ............ 9<La! endorna!, corti!ona, $rolactina &a!o$re!ina ........................................................... 9?alcohol .................................................................................................................33...3.... @8

Renina*angioten!inaActi&idad .......................................................................................3. @9Ca$+t#lo @arterialalta ..........................................................................................................33......... <5E!ca!e de ag#a4 /otenciale! $ara lahi$erten!ión ............................................................ <;Ca$+t#lo <Cole!terol en !angre!#$erior ............................................................................................ :8

 2e!timonio! (#e te hacenmeditar .................................................................................... ::Ca$+t#lo :El e%ce!o de $e!ocor$oral .................................................................................................??Comer en e%ce!o m)!E%$licado ...................................................................................... 5>>Dieta 0oda! $#eden ca#!ar a#mento de$e!o ................................................................. 5>=Ca$+t#lo ?

A!ma Alergia! ................................................................................................................ 559Ca$+t#lo 5>Dia"ete! in!#lino*inde$endiente .......................................................................33.........5;8

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El tri$tófano ladia"ete! ..................................................................................33.........

5;9La dia"ete! in!#lino*de$endiente .................................................................................... 58>Ca$+t#lo 55N#e&a! idea! !o"re el0IDA .............................................................................................. 588El de!arrollo de lo! acontecimiento! en la In&e!tigación del0IDA .................................. 5=8Ca$+t#lo 5;El m)! !im$le de lo! tratamiento! enMedicina ............................................................... 595

Facilidad deDormir .......................................................................................................3 59<$re&enir lo!de!mao! ................................................................................................3.. 59</re&enir ata(#e!card+aco! ..............................................................................................59<El color de laorina .....................................................................................................

33. 59:La! e!$erana! de c#rado a e!ta"lecido!Enfermedade! .............................................. 59:0al dieta li"re e! com$letamentee!t-$ido ..................................................................... 5@>El 0i!tema de 0al#d N#e!tra!Re!$on!a"ilidade! ......................................................... 5@8Ahorro de co!to! a laNación ............................................................................33......... 5@8nalmente ......................................................................................................33......33 5@9

De!hidratación cel#lar crónica doloro!a $remat#ramente mata. 0#!manife!tacione! e%terna! iniciale! tienen ha!ta el ahora !ido eti(#etadocomo enfermedade! de origen de!conocido.

/RL11

Una de la! raone! m)! o"&ia! $or la medicina ha llegado a !er tancom$licado co!to!o e! el hecho de (#e la in&e!tigación la $rod#cción

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de $rod#cto! farmac'#tico!*, nalmente, !# e&al#ación ha con&ertidoen $aciente mon#mentalmente caro. /ara im$#l!ar la &enta de

$rod#cto! (#e !e an#ncian con reg#laridad en gran medida, no !ólo nom# "ien $agado! m'dica re$re!entante! $re!entan !# arg#mento de&enta, $ero lo! m'dico! tam"i'n !on atra+do! hacia la $romoción de lo!medicamento! $or $arte de lo! 7"enecio!7 ofrecido. Lo! $aciente!!ig#en #!ando $or(#e no !e c#ran. No !e !#$one (#e de"en !erc#rado! Ello! !on !ólo tratar E!ta e! la forma ideal de (#e elmercantili!mo en la medicina $#ede $ro!$erar. E!ta no e! la -nica !#elta&ergono!a terminar en la medicina.

0e hacen $o!i"le! lo! a&ance! orientado! 2'cnica! de la medicina, comore!#ltado de la $rod#cción de 7artil#gio!7. E!to, tam"i'n, a#menta el

co!to de la medicina. La en!eana de lo! ho!$itale! lo! centro! dein&e!tigación de$enden en gran medida de la nanciación de la a!$ectoind#!trial del !i!tema de atención de !al#d. /or lo tanto, la in&e!tigaciónen medicina tradicionalmente !e ha dirigido de ac#erdo con la de!eo! delo! ind#!triale! de la !al#d (#e li"eran fondo! $ara !#! $ro$io! $roecto!(#e generen ganancia!.

Ahora &iene #n momento de gran regocijo. 0e ha de!c#"ierto (#e elc#er$o h#mano $o!ee #na &ariedad de indicadore! !o!ticado! c#ando!e ejec#ta $or de"ajo de lo! indicadore! de emergencia de ag#a dede!hidratación !ed. El c#er$o tiene m#cho! m)! (#e el indicador de

7"oca !eca7 de la e!ca!e de ag#a. Ig#almente o"&io, la maor tragediade la medicina la hi!toria e! el hecho de (#e lo! $rofe!ionale! de lamedicina no han entendido la &ariedad del c#er$o h#mano de la!con&ocatoria! de ag#a. ello! han rec#rrido tradicionalmente a la#tiliación de $rod#cto! (#+mico! lo! 7$rocedimiento!7 $ara hacerfrente a la de!hidratación crónica del c#er$o. la error mon#mental, !ino#n hecho agranteEl corte m)! cr#el de todo e! la forma en (#e la com#nidad m'dicacon&encional !ig#e $reriendo a adherir!e a la normalidad $a!a $oralto la! "#ena! noticia!. F#ndamentalmente, e!ta ignorancia ")!ica dela! manife!tacione! de la! nece!idade! de ag#a de la c#er$o h#mano e!

la $rinci$al raón $ara el alto co!to de la atención de la !al#d en n#e!tra!ociedad, !in e!$erana de mejora en la forma en (#e e!t) m# maldi!eo (#e !ólo !ir&e a !#! o$eradore! no a la atención de la !al#d*lanece!idad de #n di!eo*act#almente $-"lica.0i #!ted &a a mirar la! carta! intercam"iada! con la A!ociación M'dicaAmericana AMAG, im$re!o! en la $arte nal de la li"ro, !e dar) c#entade (#e m#cho ante! de la $#"licación de e!te li"ro, la AMA f#e in&itadoa con&ertir!e en el heraldo de la la "#ena noticia, 7no e!t)n enfermo!,

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tener !ed,7 al $-"lico. 0# -ltimo !ilencio e%$one claramente !# agrante&iolación de la conana $-"lica.

El In!tit#to Nacional de 0al#d NIHG, el centro m)! a&anado de lain&e!tigación m'dica en el m#ndo, ha fallado la !ociedad a-n m)!mi!era"lemente. En $rimer l#gar, $or (#' no ha e!t#diado lo! efecto!medicinale! de ag#a 6/or (#' no !e !e$aró de la $o!i"le im$acto$o!iti&o de ag#a tomada de tragar #na $+ldora de la 7medicina7 en !+ mi!mo 6/or (#' no e!t#diar lo !#cede a #na $er!ona (#e no "e"ereg#larmente ag#a E!ta! !on !#! errore! iniciale!. 6/or (#' cree! (#e elNIH con&ertir e!to! errore! en #na o$eración enc#"iertaEn mao de 5?:?,5 e!cri"ió al Dr. Jame! Ma!on, !ecretario de 0al#d 0er&icio! H#mano!, e%$licó (#e #na el cam"io de $aradigma (#eanalió la! nece!idade! de ag#a del c#er$o e%$ondr+a m#cha!

!ol#cione! a lo! $ro"lema! de !al#d de n#e!tra la !ociedad. Le en&i'todo el material de a$oo (#e !e rerió el Dr. John 2. Kal"erer,Coordinador NIH $ara la 0al#d /romoción /re&ención deEnfermedade!, $ara re&i!ar di!c#tir conmigo o"&iamente, la 1cinaadec#ado $ara la e&al#ación de lo! mi! "a!ada en !iolog+a idea!re&ol#cionaria!.No e! a!+ F#i in&itado a &i!itar con el Dr. Kal"erer. De!$#'! de ladi!c#!ión de #na hora, el Dr. Kal"erer me informó (#e el NIH no e!ta"aen condicione! de manejar mi! 7grande!7 $#nto! de &i!ta m'dico!.E%$licó (#e el NIH no $od+a nanciar la in&e!tigación en a$arte de lo!am"iente! #ni&er!itario!. Me indicó (#e el moti&o de mi contacto con el

Dr. Ma!on 'l mi!mo era e%$licar de!hidratación como la ca#!a dem#cha! enfermedade! degenerati&a! del c#er$o h#mano, de modo (#eel NIH $odr+a comenar !# e!t#diar tomar el re!#ltado al $-"lico.L#ego me dijo (#e el NIH !ólo e!ta"a intere!ado en lo! a!$ecto!molec#lare! de la in&e!tigación "iológica farmac'#tica. Indicó mi!$#nto! de &i!ta !e "a!an tan am$lia (#e no !e aj#!ta"an a la forma en(#e la in!tit#ción de in&e!tigación f#ncionó. C#ando !e dio c#enta de(#e e!ta"a de!contento con !# $ron#nciamiento, 'l me acon!ejó (#econtin#ar con mi tra"ajo $#"licar mi! o$inione!. Me dijo (#e e!ta !er+ala -nica manera en (#e con!eg#ir+an o+do.No me do $or &encido. Cada &e (#e #n art+c#lo de la !al#d a$areció en

lo! $eriódico! !o"re la "a!e de declaracione! de alg#ien en el NIH,e!cri"+ #na carta le e%$li(#' el $ro"lema de fondo. Incl#!o e!cri"+ a la1cina de Integridad Cient+ca de la NIH !e (#ejó de alg#na! $iea! dela de!información (#e !e han e!ta"lecido !ólo #n $rod#cto en $artic#laren el mercado m'dico. No he o+do de ello!, $ero el tema $arece ha"erm#erto el $orta&o fotog'nica $arece no lle&ar a ca"o la corte contanta frec#encia como ante!.

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D#rante #n tiem$o, me emocion' c#ando el Dr. Bernadine Heal !econ&irtió en el director de lo! NIH. Ella $arec+a !er la ti$o adec#ado de

$er!ona (#e cam"iar+a el NIH. Como #n MD cient+co, ella o"&iamentecom$rendió lo (#e e!ta"a diciendo.Ella me en&ió a 0te$hen roft, /h.D., (#e aca"a"a de con&ertir!e en #ndirector interino de la 1cina de reciente creación de la medicinaalternati&a ha!ta (#e #n director $ermanente MD !e $#do encontrar./arec+a #na $er!ona m# !incera. De!$#'! de #na larga re#nión ha"erle "rindado #n $oco de mi $#"licada materiale!, me in&itó a hacer#na "re&e $re!entación en la $rimera Conferencia de MedicinaAlternati&a (#e !er) con&ocada $or el NIH. 0# $o!ición tem$oral eradema!iado tem$oral a hacer ning-n "ien. Dr. Jo!e$h Jaco"! !e hiocargo. l e! #n m'dico de la medicina con la c#lt#ra india nati&a e

in#encia. E!to !eg#ro de (#e el Dr. roft ha"+a $a!ado mi información materiale! $ara 'l.La $ró%ima Conferencia de Medicina Alternati&a f#e con&ocada $or el Dr. Jaco"! !# !eg#ndo al mando, o e!ta"a en e!e tiem$o $ara !erintrod#cido a ello! $or el Dr. roft. Nat#ralmente, en e!e momento, elDr. Jaco"! no ten+a el tiem$o $ara lle&ar a ca"o #na di!c#!ión !eria. 0eacordó (#e echar #n &i!tao a lo (#e o ha"+a en&iado a la 1cina $ara no!otro! $ara !ati!facer a #na en el corto $lao. En n#e!tra re#niónen !# ocina, le $reg#nt' !i ha"+a &i!to lo (#e o ha"+a en&iado$re&iamente a !# ocina. 'l comenaron a hacer la e%c#!a de (#e eracorto de tiem$o, , al mi!mo tiem$o, (#e e!ta"an cam"iando la

#"icación de ocina! (#e no ha"+a tenido la o$ort#nidad de &er lo (#eo ha"+a en&iado. Le dije (#e !i 'l no e!t#&iera al corriente del contenidode lo! materiale! Oo ha"+a en&iado, e!ta re#nión f#e #na $'rdida de !#tiem$o el m+o (#e de"er+amo! a$laar la di!c#!ión ha!ta (#e 'lha"+a le+do el información (#e ha"+a $ro$orcionado. Me le&ant' $arairme. 2#&e (#e cortar a tra&'! de !# $o!t#ra 7$rima donna7.l me dijo (#e i"a a echar #n &i!tao a lo (#e o ha"+a en&iado, $ero a(#e e!t)"amo! tanto a $rofe!ionale! inteligente!, no ha"+a m#cha!co!a! (#e no $odr+an aclarar!e en la di!c#!ión de #na hora. Me in&itó a!entarme e%$licar mi! $#nto! de &i!ta. Oo lo hice.Ante! de irme, me $idió otra !erie de materiale! de a$oo. Lo! ten+a en

mi ca!o le! di.Entre lo! materiale! !#mini!trado! era #na co$ia de la $rimera ediciónde e!te li"ro. Le e%$li(#' (#e e!ta información e! con&ertir!e enconocimiento $-"lico. Lo in&it' $or el "ien de la !ociedad el a&ance dela ciencia m'dica $ara comenar la e!t#dio de !# tema a tra&'! de !#1cina.No e!c#ch' del Dr. Jaco"! o lo &eo ha!ta la $ró%ima Conferencia deMedicina Alternati&a. Nada !o"re crónica de!hidratación e!ta"a en la

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agenda. Incl#!o c#ando el coronel Ro"ert 0ander!, (#ien e!t) m# "ien&er!ado en el tema, hio #na cinco min#to! de $re!entación lo!óca

!o"re la de!hidratación, no !e tomaron medida! $ara $oner el temaante! de (#e el A!e!or J#nta. P#edó claro (#e la 1cina de MedicinaAlternati&a ten+a !# $ro$ia agenda, !er&ir al $-"lico no e!ta"a en !#li!ta de $rioridade!.0eg-n Rita Mae BroQn, 7La denición de loc#ra e! hacer la mi!maem"aldo!ado #na otra &e e!$erar (#e lo! re!#ltado! !eandiferente!. 7E! de !#$oner (#e de ac#erdo con e!ta denición, o !o#no de lo! m)! loco!. A men#do creo a m+ mi!mo como #n !im$lón. Me$reg#nto a mi mi!mo4 6/or (#' ga!tar tiem$o rec#r!o! $er!onale!$ara lograr #na tran!formación "a!ada en la ciencia de la medicina en,de todo! lo! l#gare!, lo! E!tado! Unido! En la !ig#iente re!$iración Me

con!#elo $en!ando (#e E!to al tanto de la !al#d &ital la informaciónde "iene!tar (#e tiene (#e llegar a la gente inocente la conana (#e!e con&ierten en enfermo! no !a"en (#e !on !ólo !ed de ag#a. Cone!te $en!amiento me &o el $ró%imo tramo de mi camino can!ado.Mientra! tanto, el Dr. Bernadine Heal dejó el NIH. Ella e! #n m'dico. ElN2H e! #na in!tit#ción de la 7ciencia7.1"&iamente tiene (#e ha"er ha"ido #n conicto de o"jeti&o (#e ten+a(#e ir!e. /remio No"el Harold arm#! !e hio cargo.Una &e m)!, en el ;8 de no&iem"re de 5??85, le e!cri"ió. Comenc' micarta4 7Bien&enido a la $o!ición (#e ahora $#ede hacer #na maorcontri"#ción al a&ance de la ciencia m'dica la !ociedad. De ho del

Sa!hington /o!t art+c#lo !o"re el (#e me im$#l!ó a e!cri"ir e!ta carta lle&ar #n a&ance de im$ortancia en la ciencia m'dica $ara !# atención.TE! la de!hidratación crónica (#e e! la ca#!a f#ndamental de la!enfermedade! m)! im$ortante!.T He intentado en el $a!ado $arao"tener el NIH $ara tomar #na mirada !eria a e!ta !im$le 7cam"io de$aradigma7 hacer (#e la f#t#ra $r)ctica de la medicina $ara el$aciente 7, me le en&ió #no de mi! li"ro! alg#no! materiale! de a$oo./ara lata! fecha, fe"rero de 5??9, no he !a"ido nada de e!to ca"allero,ni !i(#iera #na carta de agradecimiento.1"&iamente, la -nica manera de lle&ar el men!aje de 7de!hidratación7 al$-"lico era e!cri"ir. E!o lo hice. De!$#'! de en&iar carta! a &aria!

re&i!ta! $eriódico! no !a"er de ello!, decidieron, en 5?:?, $ara crearn#e!tra $ro$ia re&i!ta en la F#ndación $ara el 0im$le en Medicina. Lollamamo! Ciencia en Medicina !im$licado. Un e!$ecial emi!ión #nn-mero reg#lar de la re&i!ta !e $#"licaron en #n $er+odo de #n ao !edi!tri"#e grat#itamente a alg#no! centro! de in&e!tigación "i"lioteca! m'dica! en alg#na! #ni&er!idade!. 2am"i'n !e a$lica a la Bi"lioteca Nacional de Medicina de lo! diario!$ara !er inde%ado! en el ordenador Inde% Medic#! !i!tema $ara (#e !#

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contenido !e $od+a acceder $or otro! in&e!tigadore!. A$elamo! a (#eno! $agar #n ig#al o$ort#nidad de $re!entar n#e!tro 7cam"io de

$aradigma7 in&e!tigado &i!ta! en la medicina. Llegaron de n#e&o ano!otro! dijeron do! &ol-mene! de #na $#"licación no era !#ciente,$ero #na &e (#e otro &ol#men f#e $#e!to f#era e!t)"amo! !eg#ro! de(#e i"a a !er contin#idad, !e con!iderar+a la $o!i"ilidad de inde%ación dela! re&i!ta!.El tercer &ol#men de la re&i!ta e!ta"a en lo! tra"ajo! en e!ta eta$a ,c#ando !e $#"licó en 5??5, hemo! en&iado n#e!tro a$licación do!&ol-mene! de cada $#"licación a la NLM. Re&i!ta! !e e&al-an do! o tre!&ece! al ao $ara !# $o!i"le incl#!ión en el Inde% Medic#!. El comit'e!t) formado $rinci$almente cient+co! del NIH. C#ando !e encontraronen Al nal del ao re&i!ado n#e!tra n#e&a información en medicina,

(#e f#eron rechaado!. Ello! no no! (#ieren dar #na ig#aldad deo$ort#nidade! $ara n#e!tra! o$inione! !ean e!c#chada!. Lo!7$en!adore!7 del NIH no de!ea"an n#e!tro! n#e&o! $en!amiento! $araentrar en la com#nidad cient+ca arena , nalmente, llegar al $-"lico.No! h)"ilmente cen!#rado!. E! entonce! c#ando me decid+ a e!cri"ir la$rimera edición dee!te li"ro hacerlo $-"lico.Cerca de !ei! me!e! de!$#'! de la negati&a NLM, mi li"ro e!ta"a f#era e!t) re$a!ando. Ahora ten+a #n leng#aje !encillo e%$licación de donde lamedicina con&encional ha"+a !alido mal. E!te f#e el li"ro (#e me en&ió,adem)! de la cient+ca $#"licacione!, a lo! Dre!. Heal, roft Jaco"!

en el NIH. P#er+a (#e !#$ieran (#e no lo! nece!ita"a $ara mi! &i!ita! allegar al $-"lico. Me ha"+a dado c#enta de (#e el NIH !e a#to*intere!adamente !ati!fecho con la loc#ra de la realiación la re$eticiónlo! mi!mo! ti$o! de in&e!tigación !in la "-!(#eda de #na c#ra $araning#na de la! enfermedade! degenerati&a! del c#er$o h#mano.En a"ril de 5??8, !e $rod#jo #n Bio*o%idati&a Conferencia M'dicaInternacional en Re!ton, irginia. F#i in&itado a ha"lar de!$#'! de la/re!identa de la A!ociación. E!ta e! #na de la! conferencia! con&ocada!$or lo! $racticante! de la Medicina Alternati&a. Me $re!entaron a #na dela! 0ecretar+a! de cient+co! del NIH, el Dr. Edm#nd 0argent Co$eland,(#ien f#e in&itado a re&i!ar la conferencia. De!$#'! de mi charla !o"re

el $a$el de la hi!tamina como el $rinci$al reg#lador de ag#a del c#er$o,di!c#tió m# gentilmente cómo $odr+a tener '%ito en con!eg#ir mi!$#nto! e&al#ado!. Le en&i' la maor $arte de mi $#"licadamateriale!. No! re#nimo! en !# ocina Se!t"ard A&en#e. l hio todo lo$o!i"le $ara (#e me in&itaron $or el director del $rograma de !#!conferencia! $ara ha"lar ante !#! miem"ro!. La in&itación n#nca llegó.E! o"&io mi! $en!amiento! !on #na amenaa $ara la contin#ación dealg#no! de lo! enfo(#e! de lo! NIH a la in&e!tigación m'dica.

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Nat#ralmente, mi! $#nto! de &i!ta no !e le! $ermitir) hacer eco en la!$arede! de lo! NIH. P#ieren a#tómata g#!ta $re!entar mi hallago! en

#na manera (#e !ea ace$ta"le $ara ello! !ólo. E!a e! la forma en (#e lotienen a !# manera.He tratado de darle información detallada acerca de mi! e!f#ero! $aracon!eg#ir (#e la! $er!ona! (#e tienen a !# cargo la re!$on!a"ilidad dec#idar de lo! intere!e! de !al#d de la nación $ara tra"ajar en !# nom"re.Como &e!, eligieron !# $ro$io manera &entajo!a de negocio! como deco!t#m"re. Ahora e! (#erido (#e la! in!tit#cione! (#e #!an !#! dólare!de im$#e!to! #n im$ortante $arte de !#! ingre!o! d#ramente ganadono le! im$orta ni #n )$ice de !# !al#d "iene!tar. Ahora e! o"&io (#ea(#ello! (#e $retende !er !olicitante! de !ol#ción !on lo! $romotore! de!# $ro"lema. A $artir de a(#+, #!ted, lo! lectore! de la información en

e!te li"ro, tiene (#e con&ertir!e en #na $arte de la f#era detr)! de latran!formación del !i!tema de !al#d en Am'rica.1"&iamente, el nanciamiento $ara la e&al#ación del ag#a como #namedicina nat#ral no $arece !er f)cil de con!eg#ir. Adem)!, incl#!o !i lo!fondo! i"an a !er $#e!to! a di!$o!ición, la in&e!tigación del tema no$arece lo !#cientemente atracti&a $ara la! #ni&er!idade! centro! dein&e!tigación reconocido! a ni&el nacional. O, !in em"argo, $ara mo!trara lo! dem)!, la re!$#e!ta del $aciente al tratamiento con el ag#a como#n medicina nat#ral en la! enfermedade! $rod#cida! $or lade!hidratación crónica e! nece!ario. E! nece!ario con&encer a la lo!m'dico! dentro del !i!tema de atención de !al#d a cam"iar !# enfo(#e

act#al del tratamiento. Lo! e!t#diante! en la! e!c#ela! de medicina noen!ean nada acerca de la! m#cha! f#ncione! del ag#a en el c#er$oh#mano. 2al como o lo &eo, &amo! a nece!itar m#cha! o"!er&acione! 7!im$le! directo!7, como lo! (#e c#a! carta! !e $#"lican en e!te li"ro, $arainformar de !#! hallago! ante! de (#e lo! $rinci$ale! $rofe!ionale! dela medicina a"andonar+an !# m'todo de tratamiento.0# m'todo $re!ente !ólo e! adec#ado $ara la $romoción de lo!$rod#cto! (#+mico!. 7Do"le*ciego en!ao! aleatorio!7 !ólo !on adec#ado$ara la e&al#ación de #n $rod#cto (#+mico a otro, !#!tancia meno!conocido. E!ta metodolog+a $artic#lar e! no e! adec#ado $ara la

e&al#ación cl+nica de lo! 7tra!torno! de deciencia,7 en e!te ca!o lo!efecto! del ag#a !o"re la &ariedad de enfermedade! de!hidratación$rod#cida.E!tado! !iológico! del c#er$o de cada indi&id#o determina lo! !+ntoma! com$licacione! de la de!hidratación inicial.E! $or e!o (#e e!to! e!tado! de de!hidratación !+ntoma! (#e$rod#cen tradicionalmente han !ido eti(#etado! como m#cha!enfermedade! diferente! condicione!. C#ando #!ted e!t) en el li"ro,

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#!ted entender) lo (#e e!to diciendo. 2am"i'n leer) alg#na! letra!c#o! a#tore! ten+an m)! de #no de lo! $rimero! !igno! de la e!ca!e

de ag#a recientemente reconocida en el c#er$o.Ahora no! encontramo! en lo! al"ore! de #na n#e&a era en la cienciam'dica. T0e trata de la e!ca!e crónica de ag#a en el c#er$o (#e ca#!ala maor $arte de la! enfermedade! del c#er$o h#mano. 7El di!eooriginal del c#er$o h#mano e! m)! com$leta (#e !e $#eda imaginar.0i no hemo! !a"ido mantener ha!ta ahora, e! n#e!tra $ro$ia c#l$a. Nono! hemo! $arado a $en!ar, !i el c#er$o e! $rinci$almente ag#a, 6dónde&a a con!eg#ir !# com$letarlo !i no "e"emo! ag#a !o"re #na "a!ereg#lar Ahora !a"emo! c#ando !e e!t) llamando $or !# inge!ta#rgente. 2enemo! (#e in!i!tir en e!ta información. Em$#jar el ag#a noe! #n tr#co de $er!onal. No ha agenda oc#lta a !# $romoción. 0i #!ted

com$arte e!ta información con !#! !ere! (#erido!, (#e !on !#!"eneciario!.En la act#alidad, e!te li"ro e! la -nica f#ente de información f)cil deentender de lect#ra en la de!hidratación crónica. #!ted tener (#e leer#n $ar de &ece! entender la $rof#ndidad de la f#nción indi!$en!a"lede ag#a en el c#er$o h#mano.0i #!ted hace e!to, #!ted !e con&ertir) en #n !anador tam"i'n. En e!teli"ro, #!ted tam"i'n tendr) (#e a$render (#e 7#ido!7 7ag#a7 no !onnece!ariamente la mi!ma. U!ted a$render) acerca de lo! efecto!$erj#diciale! de la! ga!eo!a! diet'tica!.0i #!ted enc#entra la información de e!te li"ro -til, $or fa&or, le&anten la

&o gritar contra el lado o!c#ro feo de la medicina (#e !e $ractica enla act#alidad. Lo! m'dico! !e !#$one (#e !on !anadore!. Ello! hantomado #n j#ramento $ara !er&ir h#manidad. E! cierto (#e el 7negociode Am'rica e! el negocio7, $ero mi! colega! con mentalidad comercial,no tienen derecho a o"!tr#ir el !im$le men!aje de 7no e!t) enfermo,tiene !ed,7 de llegar a #n !ector m)! am$lio del $-"lico.Ello! no tienen nada (#e con&ertir el dolor el !#frimiento de !#!!emejante! en la! $r)ctica! comerciale! ac#m#lati&o! (#e hemo!o"!er&ado en el $a!ado reciente. Oo h#mildemente reconoco (#e no todo! lo! m'dico! $onen !# $ro$io"enecio ante! de (#e el "iene!tar de lo! (#e "#!can !# hone!ta

con!ejo. 0ólo tiene! (#e echar #n &i!tao a la cantidad de m'dico! en la$e(#ea li!ta de la! re!ea! del li"ro $ara &er e!te hecho.0ólo #na m# $e(#ea minor+a, $or de!gracia, en $#e!to! de go"ierno,han arrojado #na mala l# !o"re n#e!tra $rofe!ión !agrada.0in em"argo, 7c#ando lleg#e la l#, la o!c#ridad tiene (#e ir.7 C#ando lagente comiena a com$render (#e el ag#a $or !+ !ola e! la mejormedicina nat#ral en m#cha! condicione! de la 7enfermedad7 del c#er$o,

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el gar"ano negro de la $rofe!ión de la medicina !agrada &ol#ntad lle&ar!# negocio a otra $arte.

 2radicionalmente, lo! m'dico! han !ido lo! $en!adore! ló!ofo!. E!!ólo recientemente (#e !e han &i!to o"ligado! a memoriar lainformación $re*digerida $ara o"tener a tra&'! del $lan de e!t#dio! enlo! ho!$itale! docente!. En realidad, !e crean lo! li"ro! $ara almacenarla información, el cere"ro e!t) di!eado $ara 7$en!ar7. Una &e (#eno! de!hacemo! de la carga de tener (#e recordar lo (#e m#chade!información generada en torno a la! condicione! (#e !oncom$licacione! de la de!hidratación crónica, el n#e&o lo! m'dico!&ol&er)n a !er !a"io! $en!adore!. E! entonce! c#ando !#!$ron#nciamiento! !ean re!$etado! &erdaderamente &alen !# $e!o enoro, nada meno! (#e tarifa de honorario! de lo! cir#jano!.

Con la e!$erana de #na n#e&a era de la! l#ce! "rillante! de lamedicina, me g#!tar+a (#e lo! lectore! de e!te li"ro la !#erte de !# $arteindi!$en!a"le en la tran!formación de la e!tr#ct#ra act#al de lamedicina. Cada carta (#e !e $#"lica en el li"ro no e! m)! (#e #nam#e!tra de lo (#e 7el ag#a como medicina7 $#ede hacer en millone! de$er!ona! (#e $re!entan manife!tacione! e%terna! !imilare! dede!hidratación crónica. la arrogante! e ignorante! en la $r)ctica m'dica!e eti(#ete e!ta! carta! como 7anecdótico7 dejarla! de lado.Innitamente maore! en n-mero, al &er lo! ojo! conectado! a $en!arcere"ro! reconocer) en cada #no de ello! la n#e&a &erdad, T#!ted Noe!t) enfermo, tiene !ed 7, (#e an#ncia el n de la $re!ente $icad#ra

m'dica contra el $-"lico.E!te li"ro e!t) de!tinado a !er le+do como #na 7no&ela7 !o"re la relaciónde amor del ag#a el c#er$o h#mano. No lo e! di!eado $ara !er le+do$or 7!o#nd"ite!.7 E!ta e! la raón $or la (#e no tiene #n +ndice.Me g#!tar+a dar la! gracia! a mi e!$o!a iao$o $ara amarla a$oo a#da.Me g#!tar+a dar la! gracia! a coronel Ro"ert 2. 0ander! $or !#!incan!a"le! e!f#ero! en lo! -ltimo! cinco ao! en con!eg#ir mi! $#nto!de &i!ta !o"re de!hidratación crónica a !er o+do $or la gente (#e $ien!a(#e $odr+a (#erer a#dar a !# $ro$agación. 2am"i'n me g#!tar+a agradecer a todo! a(#ello! (#e han !ido

$artidario! de e%#"erante! han animado a (#e o contin#ara no !ecan!ar)n. /or -ltimo, me g#!tar+a dar la! gracia! a la 0ra. DorothHeindel $or !# editorial de todo! mi! man#!crito! li"ro!.

F. Batmanghelidj, Doctor de fe"rero 5??9introd#cciónN1 2RA2E LA 0ED C1N MEDICAMEN210

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Lo! $ro"lema! !ignicati&o! (#e tenemo! no !e $#eden re!ol&er en elmi!mo ni&el de $en!amiento con (#e lo! creamo!. 7

*Al"ert Ein!teinEn diciem"re de 5??>, el Dr. Lo#i! 0#lli&an, el 0ecretario de 0al#d 0er&icio! H#mano!, re$ortó #n a#mento del 55 $or cientoen el co!to de la $re!tación de atención de !al#d $ara la nación. E!teco!to !e e!tima (#e alcanar) V 5,@>>,>>>,>>>,>>> $or el ao ;>>> $aracon!#men el ;:W del /NB $ara el ao ;>5>, !i !e $ermite (#e contin-ela tendencia act#al. 2he Sa!hington /o!t, en #na de !#! reciente! an)li!i! de c#idado de la!al#d, ha e!timado lo! co!to! de atención de la !al#d 5??= har+allegar a V 5,>;?.@ millone! de dólare!. De e!ta cantidad, ?8=,: mil

millone! dólare! e! lo! co!to! de !al#d $er!onale! inc#rrido! $or el$-"lico. El federalo"ierno !e dice (#e e! re!$on!a"le de !ólo V ?=.: mil millone! delga!to. 0in em"argo, e!te enorme ga!to !e con&ierte enla "a!e im$oni"le de lo! ?,9 millone! de $er!ona! em$leada! en laact#alidad en el !i!tema de !al#d en E!tado! Unido!. E! (#erido (#eel go"ierno !e "enecia de la !#"ida de lo! co!to! de atención de la!al#d de la nación. /or lo tanto, e%i!te #n conicto deintere!e! entre la! nece!idade! de la $o"lación la intención delgo"ierno $ara $re!er&ar !# "a!e de ingre!o!.A la l# de e!te entendimiento, $odemo! &er $or (#' el go"ierno no

e!tar+a intere!ado en la ado$ción de medida! $ara red#cir elc#idado de la !al#dco!to! del $#e"lo e!tado#niden!e, a $e!ar de (#e !on $or ahoracon!ciente de la "a!e del $ro"lema. 0e hace e&idente(#e la! $er!ona! !on re!$on!a"le! de !# $ro$ia !al#d. 2ienen (#e$roteger!e de comercialcon!ideracione! de lo! o$eradore! de !er&icio! de !al#d el go"ierno(#e (#iere mantener lo! co!to! de atención de !al#d en la act#alidadni&ele!.U!ted &e, la cri!i! de la atención de !al#d de Am'rica (#e a la"ancarrota al $a+! !i !e $ermite (#e contin-e en !# tendencia act#al, e!

no ca#!ado $or la forma en (#e !e o$era. 2am$oco e! enteramente elre!#ltado de $recio! "a!ado en la codicia. E! ca#!ada $or #na m)!error $rimiti&o en la $remi!a ")!ica en la ciencia de la !iolog+a (#e e!la "a!e $ara todo el $er!onal m'dico cient+coconocimiento del c#er$o h#mano. E! ca#!ada $or(#e el $-"lico lo!$rofe!ionale! no !a"en a-n c#ando elc#er$o h#mano tiene !ed de ag#a

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E!ta !it#ación no tiene $or (#' !eg#ir !iendo o llegar a !er tande!e!$erada como $arece. M# e%ten!a! o"!er&acione! cl+nica!

!o $ena di!$'$tico la in&e!tigación e&al#ati&a en la !iolog+a de lo!dolore! crónico! mo!trar #n !im$le f#ndamental!ol#ción al $ro"lema de la atención !anitaria de la nación e!t)di!$oni"le. La "ellea de e!ta !ol#ción e! (#e e! enteramente la ciencia*"a!ado. 0e trata de #na n#e&a com$ren!ión !iológica del c#er$oh#mano. La n#e&a información !o"re el c#er$o h#mano,como #!ted de"e ha"er adi&inado $or el t+t#lo del li"ro, !ig#e.6/1R PU 7MEDICINA7 N1 c#ra la enfermedadLo! $rofe!ionale! m'dico! de ho en d+a no entienden la! f#ncione!&itale! de ag#a en el c#er$o h#mano.Lo! medicamento! !on $aliati&o!. No e!t)n di!eado! $ara c#rar la!

enfermedade! degenerati&a! del c#er$o h#mano.En e!te li"ro, &amo! a di!c#tir el $a$el del ag#a en el c#er$o como #na"re&e com$ren!ión de e!te tema $#ede tran!formarla! nece!idade! de !al#d de n#e!tra !ociedad. amo! a a$render cómola medicina $re&enti&a $#ede llegar a !er el $rinci$al enfo(#e $ara la!al#dla atención en c#al(#ier !ociedad. En e!te li"ro, en la di!c#!ión (#e!ig#e, el h'roe e! el ag#a. amo! a mirar cadae%$licación con la o$inión de (#e el ag#a e! la !#!tancia $rinci$al elagente $rinci$al en lo! e&ento! de r#tina (#e !e lle&ancolocar en el c#er$o h#mano. Con la f#nción $rimordial del ag#a en

mente, &amo! a &er alg#na! condicione! de enfermedad. la!e di!c#tir) falta $a$el del ag#a en !it#acione! !iológica! (#ee&ent#almente !e con&ertir) en condicione! de enfermedad.En la! 7enfermedade!7 (#e !e di!c#tir)n, #n $o!i"le $a$el inicial de la$ert#r"ación del meta"oli!mo del ag#a tendr) (#e !ere%cl#ido! ante! a!#mimo! (#e e!ta! condicione! han !ido ca#!ada! $orotro! $roce!o!. E!te e! el &erdadero!ignicado de #n enfo(#e $re&enti&o de la atención !anitaria. /rimerode"emo! e%cl#ir la! ca#!a! m)! !im$le! $ara la enfermedada$ariciónen el c#er$o l#ego $en!ar en el m)! com$licado. La !im$le &erdad e!

(#e la de!hidratación $#ede ca#!ar la enfermedad. 2odo el m#ndo !a"e (#e el ag#a e! 7"#eno7 $ara el c#er$o. /arecen no!a"er lo im$ortante (#e e! $ara el "iene!tar de #na $er!ona.Ello! no !a"en lo (#e !#cede con el c#er$o !i no reci"e !# nece!idaddiaria de ag#a. De!$#'! de e!te "re&e li"ro e!leer, #!ted tendr) #na mejor com$ren!ión de e!te tema.

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La !ol#ción $ara la $re&ención el tratamiento de enfermedade! dede!hidratación*$rod#cido e! la inge!ta de ag#a !o"re #na "a!e reg#lar.

e!tee! lo (#e &amo! a denir en e!te li"ro &amo! a di!c#tir $or (#', en lamaor+a de lo! ca!o!, la! condicione! (#e !e mencionan!on $ara !er &i!to como tra!torno! de de!hidratación*$rod#cida. 0i, $orel !im$le con!#mo de #na cantidad adicional de ag#a todo! lo! d+a!#!ted $#ede con!eg#ir mejor, #!ted no tendr) (#e $reoc#$ar!e. U!tedde"e "#!car a#da $rofe!ional !i el aj#!te a la! nece!idade! diet'tica!de !# c#er$o no a#da #n $ro"lema de !al#d contin-a $reoc#$ando a#!ted. Lo (#e !e ofrece e! la nece!ariaconocimiento $ara la $re&ención c#ra de enfermedade! dede!hidratación enfermedad.

Al nal del li"ro, c#ando la relación de de!hidratación crónica laa$arición de la enfermedad ha (#edado claro $arael lector, la información !er) facilitada en lo! aj#!te! nece!ario! en lainge!ta diaria de ag#a, la com$lementariadieta $ara $re&enir 7enfermedade! de de!hidratación7, o incl#!o c#rar, !ie! #na !it#ación totalmente irre&er!i"le no !e ha de!arrollado.L1 BX0IC1C#ando el c#er$o h#mano !e de!arrolló a $artir de la! e!$ecie! de (#e!e le! dio la &ida en el ag#a, la mi!ma de$endencia de la &ida*dando $ro$iedade! del ag#a f#eron heredado!. El $a$el del ag#a en !+ en el c#er$o de la! e!$ecie! &i&a!, la h#manidad incl#ido, tiene

no ha cam"iado de!de la $rimera creación de la &ida del ag#a !alada !# $o!terior ada$tación al ag#a d#lce.C#ando la &ida en la tierra !e con&irtió en #n o"jeti&o $ara a&anar m)!all) de la &ecindad inmediata de !#mini!tro de ag#a incl#!om)! all) de la &ida de lo! an"io!G*la a&ent#ra e!tre!ante all) de lo!l+mite!*a conocido! c#er$o renado grad#almente el ag#a*!i!tema de con!er&ación t#&o (#e !er creada $ara el de!arrollo den#e&a! e!$ecie!. E!te $roce!o de ada$tación tem$oral ade!hidratación tran!itoria tam"i'n !e con&irtió en hereditario como #nmecani!mo "ien e!ta"lecido en el c#er$o h#mano e! ahora elinfrae!tr#ct#ra $ara todo! lo! !i!tema! o$erati&o! en el c#er$o de lo!

h#mano! moderno!./ara la! e!$ecie! (#e ha"itan en el ag#a anteriore!, la a&ent#ra m)! all)de !#! l+mite! conocido! con!tit#ir+a #n gran e!tr'!,$or(#e !e !ecar+an. E!te 7e!tr'!7 e!ta"lecer+a #na !iolog+a dominante$ara la ge!tión de cri!i! de ag#a. enel ahora 7e!tre!ado7 lo! !ere! h#mano!, e%actamente la mi!matrad#cción la !iolog+a de la ge!tión de la cri!i! del ag#a

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!e e!ta"lece. El $roce!o im$lica $rinci$almente #n racionamientoe!tricto de la! 7re!er&a!7 de ag#a del c#er$o. e!

!#$one (#e el !#mini!tro de ag#a $ara la! nece!idade! inmediata! de lacarrocer+a !er) limitada. e!tión de la di!$o!iciónre!er&a! de ag#a en el c#er$o !e con&ierte en la re!$on!a"ilidad de #n!i!tema com$lejo.E!te com$lejo $roce!o de racionamiento de ag#a m#lti*ni&el ladi!tri"#ción !e mantiene en f#ncionamiento ha!ta (#e el c#er$o reci"e!eale! ine(#+&oca! de (#e !e ha tenido acce!o a #n !#mini!tro de ag#aadec#ado. /#e!to (#e cada f#nción del c#er$o e!monitoreado &inc#lado al #jo de ag#a, 7la ge!tión del ag#a7 e! la-nica forma de a!eg#rar!e de (#e #na adec#adacantidade! de ag#a !#! n#triente! tran!$ortado! $rimero llegan a lo!

órgano! m)! &itale! (#e tendr)n (#e enfrentar lidiarcon c#al(#ier n#e&o 7e!tr'!7. E!te mecani!mo !e hio cada &e m)!e!ta"lecida $or la !#$er&i&encia contra lo! enemigo! nat#rale! lo! de$redadore!. E! el !i!tema o$erati&o deniti&o $ara la!#$er&i&encia en !it#acione! de l#cha o h#ida. 2oda&+a e! la o$erati&amechani!m in the com$etiti&e en&ironment of modern life in the !ociet.1ne of the #na&oida"le $roce!!e! in the "od Qater rationing $ha!e i!the com$lete cr#elt Qith Qhich !omef#nction! are monitored !o that one !tr#ct#re doe! not recei&e morethan it! $redetermined !hare of Qater. e!tr#e for all organ! of the "od. Sithin the!e !!tem! of Qater rationing,

the "rain f#nction taYe! a"!ol#te $riorito&er all the other !!tem!Zthe "rain i! l9>th of the total "od Qeight,"#t it recei&e! 5:*;> $ercent of "loodcirc#lación.Shen the 7ration ma!ter!7 in charge of "od Qater re!er&ereg#lation and di!tri"#tion "ecome more andmore acti&e, the al!o gi&e their oQn alarm !ignal! to !hoQ that the areain (#e!tion i! !hort of Qater, &er m#ch liYethe radiator of a car gi&ing o#t !team Qhen the cooling !!tem i! notade(#ate for the #$hill dri&e of the car.In ad&anced !ocietie!, thinYing that tea, co[ee, alcohol, andman#fact#red "e&erage! are de!ira"le !#"!tit#te! for

the $#rel nat#ral Qater need! of the dail 7!tre!!ed7 "od i! anelementar "#t cata!tro$hic mi!taYe. E! cierto (#ethe!e "e&erage! contain Qater, "#t Qhat el!e the contain aredehdrating agent!. 2he get rid of the Qater the aredi!!ol&ed in $l#! !ome more Qater from the re!er&e! of the "od 2oda,modem life*!tle maYe! $eo$lede$endent on all !ort! of "e&erage! that are commerciallman#fact#red. Children are not ed#cated to drinY Qater

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the "ecome de$endent on !oda! and j#ice!.2hi! i! a !elf*im$o!edre!triction on the Qater need! of the "od. e!

not generall $o!!i"le to drinY man#fact#red "e&erage! in f#llre$lacement of the Qater need! of the "od. al!ame time, a c#lti&ated $reference for the ta!te of the!e !oda! Qilla#tomaticall red#ce the free #rge to drinY QaterQhen !oda! are not a&aila"le.C#rrentl, $ractitioner! of medicine are #naQare of the man chemicalrole! of Qater in the "od. $or(#edehdration e&ent#all ca#!e! lo!! of !ome f#nction!, the &ario#!!o$hi!ticated !ignal! gi&en " o$erator! of the"odT! Qater rationing $rogram d#ring !e&ere and la!ting dehdrationha&e "een tran!lated a! indicator! of

#nYnoQn di!ea!e condition! of the "od.2hi! i! the mo!t "a!ic mi!taYethat ha! de&iated clinical medicine. tiene$re&ented medical $ractitioner! from "eing a"le to ad&i!e $re&enti&emea!#re! or o[er !im$le $h!iologic c#re! for!ome major di!ea!e! in h#man!.Sith the a$$earance of the!e !ignal!, the "od !ho#ld "e $ro&ided QithQater for the!e rationing !!tem! todi!tri"#te.HoQe&er, medical $ractitioner! ha&e "een ta#ght to !ilencethe!e !ignal! Qith chemical $rod#ct!. deco#r!e the ha&e ero #nder!tanding of the !ignicance of thi! mo!tgro!! error. 2he &ario#! !ignal! $rod#ced "

the!e Qater di!tri"#tor! are indicator! of regional thir!t and dro#ght of the "od. At the on!et, the can "e relie&ed" an increa!ed intaYe of Qater it!elf, et the are im$ro$erl dealt Qith" the #!e of commercial chemical $rod#ct!#ntil $atholog i! e!ta"li!hed and di!ea!e! are "orn. It i! #nfort#natethat thi! mi!taYe i! contin#ed #ntil the #!e ofmore and more chemical! to treat the other de&elo$ing !m$tom! andcom$lication! of dehdration "ecome!#na&oida"le, and then the $atient die!. 2he iron 2he !a the $atientdied of a di!ea!e. Shat a clearance for theircon!cience

 2he error in !ilencing the di[erent !ignal! of Qater !hortage! of the "odQith chemical $rod#ct! i! immediateldetrimental to the cell! of the "od of the $er!on "eing treated. 2hee!ta"li!hed !ignal*$rod#cing chronicdehdration al!o ha! a $ermanentl damaging im$act on !#"!e(#entde!cendant! of the $er!on.I taYe $lea!#re in "ringing to o#r attention a "reaYthro#gh YnoQledgein medicine that can "enet e&er $er!on

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Qho ma fall ill, and e!$eciall the elderl. In !hort, m $aradigm changein "a!ic h#man a$$lied !cience Qill

e!ta"li!h a $h!iolog*"a!ed a$$roach to f#t#re h#man re!earch and!im$lif the $ractice of medicine all o&er them#ndo.2he immediate o#tcome of thi! $aradigm !hift Qill "e to thehealth ad&antage of the $#"lic.It Qill e%$o!e theneQl #nder!tood !ign! of dehdration in the h#man "od. It Qill al!odecrea!e the co!t! of falling ill. 2HE /ARADIM 2HA2 NEED0 21 BE CHANEDShat i! a $aradigm and hoQ doe! it change A $aradigm $ara*dimeG i!the mo!t "a!ic #nder!tanding on QhichneQ YnoQledge i! generated.A! an e%am$le, the earlier #nder!tandingQa! that the Earth i! at. El n#e&o

#nder!tanding i! that the Earth i! ro#nd. 2he ro#ndne!! of the Earth i!the "a!ic $aradigm to the de!ign of all ma$!,glo"e!, recognition of !tar! in the !Y, and calc#lation! for !$ace tra&el. 2h#!, the earlier $aradigm for holding theEarth to "e at Qa! inacc#rate. It i! the correct #nder!tanding of theEarth a! a !$here that ha! made ad&ancementin man eld! of !cience $o!!i"le.2hi! change in $aradigm i! "a!ic too#r $rogre!! in man eld! of !cience. la!hift in that $aradigm and the tran!formation it "ro#ght a"o#t did notocc#r ea!il. Ado$tion of a f#ndamentall!ignicant neQ $aradigm in the !cience of medicine i! more di\c#lt

e&en if the o#tcome i! highl de!ira"le andde!$eratel needed " the !ociet. 2HE 01URCE 1F ERR1R IN MEDICINE 2he h#man "od i! com$o!ed of ;9 $ercent !olid matter the !ol#teG and<9 $ercent Qater the !ol&entG. cere"roti!!#e i! !aid to con!i!t of :9 $ercent Qater. Shen the $ha!e of in(#irinto the QorYing! of the "od "egan,"eca#!e the !cientic $arameter! and a &er "road YnoQledge of chemi!tr had alread "ecome Qell*e!ta"li!hed, ita#tomaticall "ecame the a!!#m$tion that the !ame #nder!tanding!that Qere de&elo$ed Qithin the di!ci$line of

chemi!tr a$$lied to the "odT! !ol#te com$o!ition.It Qa! therefore a!!#med that the !ol#te com$o!ition i! the reacti&ereg#lator of all f#nction! of the "od. At the &eron!et of re!earch into the h#man "od, the Qater content of the "odQa! a!!#med to act onl a! a !ol&ent, a !$aceller, and a mean! of tran!$ortZthe !ame &ieQ! that Qere generatedfrom the te!t*t#"e e%$eriment! in chemi!tr.

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No other f#nctional $ro$ertie! Qere attri"#ted to the !ol&ent material. 2he "a!ic #nder!tanding in todaT! 7!cientic7

medicineZQhich ha! "een inherited from an ed#cational $rogram!e!ta"li!hed at the daQn of !!tematic learningZal!o regard! !ol#te! a! reg#lator! and Qater a! onl a !ol&ent and amean! of material tran!$ort in the "od. lah#man "od i! e&en noQ regarded a! a large 7te!t t#"e7 f#ll of !olid! of di[erent nat#re and the Qater in the "od a!a chemicall in!ignicant 7$acYing material.7In !cience, it ha! "een a!!#med that it i! the !ol#te! !#"!tance! thatare di!!ol&ed or carried in the "lood and!er#m in the "odG that reg#late all the acti&itie! of the "od. 2hi!incl#de! the reg#lation of it! Qater the !ol&entG

intaYe, Qhich i! a!!#med to "e Qell*reg#lated. It i! $re!#med, "eca#!eQater i! freel a&aila"le and one doe! notha&e to $a for it, that the "od ha! no "#!ine!! in falling !hort of !omething that i! a&aila"leUnder thi! erroneo#! a!!#m$tion, all the h#man a$$lied re!earch ha!"een directed toQard identication of one7$artic#lar7 !#"*0tance that can "e held re!$on!i"le for ca#!ing adi!ea!e. 2herefore, all the !#!$ected $o!!i"le#ct#ation! and &ariation of elemental change! ha&e "een te!tedQitho#t a clear*c#t !ol#tion to a !ingle di!ea!e$ro"lema.Accordingl, all treatment! are $alliati&e and none !eem! to

"e c#rati&e e%ce$t for "acterial infection! andthe #!e of anti"iotic!G. H$erten!ion i! not generall c#red it i! treatedd#ring the lifetime of a $er!on. A!thma i! notc#red inhaler! are the con!tant com$anion of the a]icted. /e$tic #lceri! not c#red antacid! ha&e to "e near" allel tiem$o.Allerg i! not c#redthe &ictim i! alQa! de$endent onmedication.Arthriti! i! not c#red, it e&ent#allcri$$le!, and !o on.Ba!ed on thi! $reliminar a!!#m$tion of the role of Qater, it ha! "ecomea $ractice to regard the 7dr mo#th7 a! a!ign and !en!ation of "od Qater need!, Qhich i! f#rther a!!#med to "e

Qell*reg#lated if the !en!ation of 7drmo#th7 i! not $re!ent, $o!!i"l "eca#!e the !#"!tance Qater i!a"#ndant and free. 2hi! i! an a"!#rdl erroneo#!and conf#!ion*generating &ieQ in medicine and entirel re!$on!i"le forthe lacY of !#cce!! in nding $ermanent$re&enti&e !ol#tion! to di!ea!e emergence in the "od, de!$ite !o m#chco!tl re!earch.

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I ha&e alread $#"li!hed an acco#nt of m clinical o"!er&ation! Qhen Itreated more than 8>>> $e$tic #lcer

!#[erer! Qith Qater alone. I di!co&ered for the r!t time in medicine thatthi! 7cla!!ical di!ea!e7 of the "odre!$ond! to Qater " it!elf.Clinicall, it "ecame o"&io#! that thi!condition re!em"led a thir!t 7di!ea!e.7 Bajo el!ame en&ironmental and clinical !etting!, other 7di!ea!e7 condition!!eemed to re!$ond to Qater " it!elf. e%ten!ore!earch ha! $ro&en m clinical o"!er&ation! that the "od ha! a &arietof mo!t !o$hi!ticated thir!t !ignal!Zintegrated !ignal !!tem! d#ring reg#lation of the a&aila"le Qater attime! of dehdration. 2he com"ination of m clinical and literat#re re!earch ha! !hoQn that

the $aradigm that ha! #ntil noQ go&erned allh#man a$$lied re!earch m#!t "e changed if Qe Qi!h to con(#er7di!ea!e.7 It ha! "ecome clear that the $ractice ofclinical medicine i! "a!ed on a fal!e a!!#m$tion and an inacc#rate$remi!e. 1therQi!e, hoQ co#ld a !ignal !!temfor Qater meta"oli!m di!t#r"ance "e mi!!ed or !o "latantl ignored for!#ch a long time At the moment, the 7drmo#th7 i! the onl acce$ted !ign of dehdration of the "od. A! I ha&ee%$lained, thi! !ignal i! the la!t o#tQard !ignof e%treme dehdration. 2he damage occ#r! at a le&el of $er!i!tentdehdration that doe! not nece!!aril

demon!trate a 7dr mo#th7 !ignal. Earlier re!earcher! !ho#ld ha&erealied that, to facilitate the act of cheQing and!QalloQing food, !ali&a i! $rod#ced e&en if the re!t of the "od i!com$arati&el dehdrated.Nat#rall, chronic dehdration of the "od mean! $er!i!tent Qater!hortage that ha! "ecome e!ta"li!hed for !ometiem$o.LiYe an other decienc di!order !#ch a! &itamin C decienc in!c#r&, &itamin B decienc in "eri*"eri, irondecienc in anemia, &itamin D decienc in ricYet!, or o# name it, themo!t e\cient method of treatment of thea!!ociated di!order! i! " !#$$lementation of the mi!!ing ingredient.

Accordingl, if Qe "egin to recognie thehealth com$lication! of chronic dehdration, their $re&ention, and e&enearl c#re, "ecome! !im$le.Altho#gh m !cientic &ieQ! in medicine Qere $eer re&ieQed, "efore I$re!ented m $aradigm change informationa! a g#e!t lect#rer at an international cancer conference in 5?:<, Dr.Barr KendlerT! letter on $age 5; $rinted "

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hi! Yind $ermi!!ionG f#rther conrm! the &alidit of m !cientic &ieQ!on chronic dehdration a! a di!ea!e

$rod#ctor.A! o# Qill !ee, he ha! e&en !t#died !ome of the im$ortantreference! that I ha&e referred to to e%$lainthat chronic dehdration i! the root ca#!e of mo!t major degenerati&edi!ea!e! of the h#man "od la! enfermedade!Qho!e ca#!e Qa! not clear #ntil noQ. Referring to an medical te%t*"ooY,o# Qill !ee o&er a tho#!and $age! of&er"iage, "#t Qhen it come! to gi&ing the rea!on! for the major di!ea!e!of the h#man "od, the !tatement in allca!e! i! #niform and &er "rief4 7Etiolog #nYnoQn7 2HE NES /ARADIM7A neQ !cientic tr#th i! not #!#all $re!ented in a Qa to con&ince it!

o$$onent!. Rather, the die o[, and a ri!inggeneration i! familiaried Qith the tr#th from the !tart.7Ma% /lancY 2he neQ !cientic tr#th and le&el of thinYing a"o#t the h#man "od thatQill em$oQer $eo$le to "ecome$ractitioner! of $re&enti&e medicine for them!el&e! i! a! folloQ!4 It i! the!ol&entZ the Qater contentZthatreg#late! all f#nction! of the "od, incl#ding the acti&it of all the!ol#te! the !olid!G that are di!!ol&ed in it. ladi!t#r"ance! in Qater meta"oli!m of the "od the !ol&ent meta"oli!mG$rod#ce! a &ariet of !ignal!, indicating a

7!!tem7 di!t#r"ance in the $artic#lar f#nction! a!!ociated Qith theQater !#$$l and it! rationed reg#lation.Let me re$eat4 e&er f#nction of the "od i! monitored and $egged tothe e\cient oQ of Qater. TSater di!tri"#tion7i! the onl Qa of maYing !#re that not onl an ade(#ate amo#nt of Qater, "#t it! tran!$orted element! hormone!,chemical me!!enger! and n#trient!G r!t reach the more &ital organ!. Int#rn, e&er organ that $rod#ce! a!#"!tance to "e made a&aila"le to the re!t of the "od Qill onl monitorit! oQn rate and !tandard! of $rod#ction andrelea!e into the 7oQing Qater,7 according to con!tantl changing

(#ota! !et " the "rain. 1nce the Qater it!elfreache! the 7drier7 area!, it al!o e%erci!e! it! man other mo!t &ital andmi!!ing $h!ical and chemical reg#latoraccione!.Sithin thi! &ieQ, Qater intaYe and it! $riorit di!tri"#tion achie&e$aramo#nt im$ortance. 2he reg#latingne#rotran!mitter !!tem! hi!tamine and it! !#"ordinate agent!G"ecome increa!ingl acti&e d#ring the reg#lation of

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Qater re(#irement! of the "od.2heir action !ho#ld not "e contin#o#!l"locYed " the #!e of medication. !#

$#r$o!e !ho#ld "e #nder!tood and !ati!ed " drinYing more Qater. Iha&e made e%actl the !ame !tatement! to a"od of !cienti!t! that had gathered from all o&er the Qorld in MonteCarlo in 5?:? for a conference on the to$ic ofinammation, analge!ic!, and imm#ne mod#lator!. 2he neQ $aradigm $ermit! an incor$oration of the 7fo#rth dimen!ion of time7 into !cientic re!earch. It Qill facilitatean #nder!tanding of the damaging e[ect of an e!ta"li!hing dehdrationthat $er!i!t! and contin#e! to increa!ed#ring an d#ration of time. It Qill maYe it $o!!i"le to foreca!t the$h!iological e&ent! that Qill lead to di!ea!e

!tate! at !ome later ear!, incl#ding Qhat at $re!ent a$$ear! a! geneticdi!order!. It Qill tran!form the $re!ent7!hot*in*the*darY, !m$tom!*treating7 a$$roach to the $ractice of medicine into a !cienticall acc#rate medical artit Qill maYe $re&enti&e foreca!ting $o!!i"le. It Qill e!ta"li!h e%cellenthealth and red#ce health care co!t! toindi&id#al! and to an !ociet that fo!ter! it! !$read.0ince Qater !hortage in di[erent area! of the "od Qill manife!t &aring!m$tom!, !ignal!, and com$lication! noQla"eled a! di!ea!e!, $eo$le ma thinY Qater co#ld not "e o[ered a! anat#ral !ol#tion. Sater c#re! !o man

di!ea!e! De ning#na manera0$eaYing th#!, the !h#t their mind! to the neQ $o!!i"ilit of $re&entingand $o!!i"l e&en c#ring !o man di[erent7di!ea!e!7 that are dehdration $rod#ced. It doe! not occ#r to them thatthe onl remed for condition! that comea"o#t Qhen the "od "egin! to get dehdrated i! Qater and nothingel!e. A n#m"er of !am$le te!timonial! are$#"li!hed in di[erent !ection! of thi! "ooY to o$en the ee! of !Ye$tic!to the fact that the greate!t health di!co&erof all time! i! that Qater i! a nat#ral medication for a &ariet of healthcondition!.

Sater Reg#lation at Di[erent 0tage! of Life 2here are "a!icall three !tage! to Qater reg#lation of the "od in thedi[erent $ha!e! of life. 1ne, the !tage of lifeof a fet#! in the #ter#! of the mother left of B in Fig#re 5G. 2Qo, the$ha!e of groQth #ntil f#ll height and Qidth i!achie&ed a$$ro%imatel "etQeen the age! of 5: to ;9G. 2hree, the$ha!e of life from f#ll groQn to the demi!e of

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the $er!on. D#ring the intra#terine !tage of cell e%$an!ion, Qater for cellgroQth of the child ha! to "e $ro&ided "

la madre.HoQe&er, the tran!mitter !!tem for Qater intaYe !eem! to "e$rod#ced " the fetal ti!!#e, "#t regi!ter!it! e[ect on the mother. 2he &er r!t indicator for Qater need! of thefet#! and the mother !eem! to "e morning!icYne!! d#ring T the earl $ha!e of $regnanc. Morning !icYne!! of themother i! a thir!t !ignal of "oth the fet#!and the mother.I2 0H1ULD BE 2H1R1UHLO UNDER0211DIt i! noQ "ecoming o"&io#! that "eca#!e of a grad#all failing thir!t!en!ation, o#r "od "ecome! chronicall andincrea!ingl dehdrated, from an earl ad#lt age. Sith increa!e in age,

the Qater content of the cell! of the "oddecrea!e!, to the $oint that the ratio of the &ol#me of "od Qater that i!in!ide the cell! to that Qhich i! o#t!ide thecell! change! from a g#re of 5.5 and "ecome! almo!t >.: !ee Fig#re;G.2hi! i! a &er dra!tic change. De!de el7Qater7 Qe drinY $ro&ide! for cell f#nction and it! &ol#me re(#irement!,the decrea!e in o#r dail Qater intaYea[ect! the e\cienc of cell acti&it.It i! the rea!on for the lo!! of Qater&ol#me held in!ide the cell! of the "od. comoa re!#lt, chronic dehdration ca#!e! !m$tom! that e(#al di!ea!e Qhenthe &ariet of emergenc !ignal! of

dehdration are not #nder!toodZa! the are #ntil noQ not #nder!tood. Oo# !ee, the!e #rgent crie! of the "od forQater are treated a! a"normal and dealt Qith " the #!e of medication!. 2he h#man "od can "ecome dehdrated e&en Qhen a"#ndant Qater i!readil a&aila"le. H#man! !eem to lo!etheir thir!t !en!ation and the critical $erce$tion of needing Qater. Notrecogniing their Qater need, the "ecomegrad#all, increa!ingl, and chronicall dehdrated Qith $rogre!! in age!ee Fig#re! 5 ^ ;G. F#rther conf#!ion lie!in the idea that Qhen QeTre thir!t, Qe can !#"!tit#te tea, co[ee, oralcohol*containing "e&erage!. A! o# Qill !ee,

thi! i! a common error. 2he 7dr mo#th 7 i! the &er la!t !ign of dehdration. 2he "od can!#[er from dehdration e&en Qhen the mo#thma "e fairl moi!t. 0till Qor!e, in the elderl, the mo#th can "e !een to"e o"&io#!l dr and et thir!t ma not "eacYnoQledged and !ati!ed.SA2ER HA0 12HER IM/1R2AN2 /R1/ER2IE0

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0cientic re!earch !hoQ! that Qater ha! man other $ro$ertie! "e!ide!"eing a !ol&ent and a mean! of tran!$ort.

Not ha&ing $aid attention to the other $ro$ertie! of Qater in thereg#lation of di[erent f#nction! in the "od ha!$rod#ced the $itif#l conf#!ion! that are infra!tr#ct#re to o#r !o*called,!cience*"a!ed modern medicine._Sater ha! a rml e!ta"li!hed and e!!ential hdroltic role in alla!$ect! of "od meta"oli!mZQater*de$endentchemical reaction! hdrol!i!G. 0imilar to the chemical $oQer! of Qaterthat maYe a !eed groQ and $rod#ce a neQ$lant or a tree4 the $oQer of Qater that i! #!ed in the chemi!tr of life._ At the cell mem"rane4 the o!motic oQ of Qater thro#gh themem"rane can generate 7hdroelectric7 energ

&oltageG that i! con&erted and !tored in the energ $ool! in form of A2/and 2/ZtQo &ital cell "atter !!tem!.A2/ and 2/ are chemical !o#rce! of energ in the "od. 2he energgenerated " Qater i! #!ed in theman#fact#re of A2/ and 2/. 2he!e $article! are #!ed a! 7ca!h oQ7 inelemental e%change!, $artic#larl inla ne#rotran!mi!ión._ Sater al!o form! a $artic#lar !tr#ct#re, $attern and !ha$e that !eem!to "e em$loed a! the adhe!i&e material inthe "ondage of the cell architect#re.LiYe gl#e, it !ticY! the !olid!tr#ct#re! in the cell mem"rane together. lo

de&elo$! the !ticYine!! of 7ice7 at higher "od tem$erat#re._ /rod#ct! man#fact#red in the "rain cell! are tran!$orted on7QaterQa!7 to their de!tination in the ner&e ending!for #!e in the tran!mi!!ion of me!!age!. 2here !eem to e%i!t !mallQaterQa! or micro!tream! along the length ofner&e! that 7oat7 the $acYaged material! along 7g#ideline!,7 calledmicrot#"#le! !ee Fig#re 8G._ /rotein! and the enme! of the "od f#nction more e\cientl in!ol#tion! of loQer &i!co!it thi! i! tr#e of all therece$tor! recei&er $oint!G in the cell mem"rane!. In !ol#tion! of higher&i!co!it in a dehdrated !tateG, $rotein!

and enme! "ecome le!! e\cient $o!!i"l incl#de! the recognition of thir!t of the "odG. It folloQ! that Qater it!elfreg#late! all f#nction! of the "od, incl#ding the acti&it of all the!ol#te! it carrie! aro#nd. 2he neQ !cientic tr#th$aradigm !hiftGZ7Sater, the !ol&ent of the "od, reg#late! all f#nction!,incl#ding the acti&it of the !ol#te! itdi!!ol&e! and circ#late!7Z!ho#ld "ecome the "a!i! of all f#t#rea$$roach to medical re!earch.

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Shen the "od i! dehdrated, a$art from the e!ta"li!hment of a 7locYed*in7 dri&e for Qater intaYe, a rationing and

di!tri"#tion !!tem for the a&aila"le Qater in the "od "ecome!o$erati&e according to a $redetermined $riorit$rogramZa form of dro#ght management,It i! noQ !cienticall clear that the hi!tamine directed and o$eratedne#rotran!mitter !!tem "ecome! acti&e andinitiate! the !#"ordinate !!tem! that $romote Qater intaYe. 2he!e!#"ordinate !!tem! al!o redi!tri"#te theamo#nt of Qater in circ#lation or that can "e draQn aQa from otherarea!. 0#"ordinate !!tem! em$lo&a!o$re!!in &a!o*$re!!*inG, renin*angioten!in RAG, $ro*!taglandin!$ro!ta*glan*din, /G and Yinin! Y*ninG a!

the intermediar agent!. 0ince the "od doe! not ha&e a re!er&e of Qater to draQ on, it o$erate! a $rioritdi!tri"#tion !!tem for the amo#nt of Qater that i! alread a&aila"le orha! "een !#$$lied " it! intaYe.In the am$hi"ian !$ecie!, it ha! "een !hoQn that hi!tamine re!er&e! andtheir rate of generation are at minimalni&ele!.In the !ame !$ecie!, hi!tamine generation "ecome! e!ta"li!hedand get! $rono#nced Qhene&er the animali! dehdrated.A $ro$ortionate increa!e in the $rod#ction rate and !torage of thene#rotran!mitter hi!tamine for rationing reg#lation

of the a&aila"le Qater in dehdrated animal!Zdro#ght managementZ"ecome! e!ta"li!hed. Hi!tamine and it!!#"ordinate Qater intaYe and di!tri"#tion reg#lator!, $ro!taglandin!,Yinin!, and /AF another hi!tamine a!!ociatedagentG al!o ca#!e $ain Qhen the come acro!! $ain*!en!ing ner&e! inthe "od. 2he a"o&e 7&ieQ !hift7 in medicine e!ta"li!he! tQo major $oint! thatha&e "een di!regarded #ntil noQ. 1ne, the"od can "ecome dehdrated a! Qe $rogre!! in age. At the !ame time,it di!regard! 7dr mo#th7 a! the onlindicator of "od thir!t. 2Qo, Qhen the ne#rotran!mitter hi!tamine

generation and it! !#"ordinate Qater reg#lator!"ecome e%ce!!i&el acti&e, to the $oint of ca#!ing allergie!, a!thma, andchronic $ain! in di[erent $art! of the "od,the!e $ain! !ho#ld "e tran!lated a! a thir!t !ignalZone &ariet of thecri!i! !ignal! of Qater !hortage in the "od. 2hi! 7$aradigm !hift7 Qill noQ maYe it $o!!i"le to recognie mandi[erent a!!ociated !ignal! of general or local"od dehdration.

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 2he ado$tion of the 7&ieQ !hift7 neQ $aradigmG dictate! that chronic$ain! of the "od that cannot "e ea!il

e%$lained a! inj#r or infection !ho#ld r!t and foremo!t "e inter$reteda! !ignal! of chronic Qater !hortage in thearea Qhere $ain i! regi!teredZa local thir!t 2he!e $ain !ignal! !ho#ld "er!t con!idered and e%cl#ded a! $rimarindicator! for dehdration of the "od "efore an other com$licated$roced#re! are forced on the $atient. no*infectio#! 7rec#rring7 or chronic $ain! !ho#ld "e &ieQed a! indicator! of "od thir!t.Not recogniing the thir!t !ignal! of the "od Qill #ndo#"tedl $rod#cecom$licated $ro"lem! in the $re!ent Qa oftreatment of the!e condition!. It i! all too ea! to a!!#me the!e !ignal!

a! com$lication! of a !erio#! di!ea!e$roce!! and "egin to treat !ignal*$rod#cing dehdration Qithcom$licated $roced#re!. Altho#gh Qater " it!elf Qillalle&iate the condition, medication! or in&a!i&e diagno!tic $roced#re!ma "e forced on the $er!on. It i! there!$on!i"ilit of "oth $atient! and their doctor! to "e aQare of thedamage chronic dehdration can ca#!e in thec#er$o h#mano. 2he!e chronic $ain! incl#de d!$e$tic $ain, rhe#matoid arthriti! $ain,anginal $ain heart $ain on QalYing, or e&en atre!tG, loQ "acY $ain, intermittent da#dication $ain leg $ain on QalYingG,

migraine and hango&er headache!, coliti!$ain and it! a!!ociated con!ti$ation 0ee g#re = on $age ;8G. 2he 7&ieQ !hift7 dictate! that all the!e $ain! !ho#ld "e treated Qith areg#lar adj#!tment to dail Qater intaYe. nole!! than tQo and a half (#art! tQo and one half liter!G in ;= ho#r!!ho#ld "e taYen for a feQ da! $rior to thero#tine and reg#lar #!e of analge!ic! or other $ain*relie&ing medication!!#ch a! antihi!tamine or antacid!ZQell"efore $ermanent local or general damage can e!ta"li!h and reach anirre&er!i"le di!ea!e !tat#!. the $ro"lemha! $er!i!ted for man ear!, tho!e Qho Qi!h to te!t the $ain relie&ing

$ro$ert of Qater !ho#ld maYe !#re theirYidne! can maYe !#\cient #rine !o that the do not retain too m#chQater in the "od. Urine o#t$#t !ho#ld "emea!#red again!t Qater intaYe. Sith increa!e in Qater intaYe, the #rineo#t$#t !ho#ld al!o increa!e. 2hi! neQ #nder!tanding of the $h!iolog of $ain $rod#ction indehdration Qill !hed light on ca#!e of di!ea!e in

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f#t#re medical re!earch. It e%$o!e! a! detrimental to the Qell*"eing of the "od the long*term #!e of $ain

medication! for 7Yilling7 a cardinal !ignal of chronic and localdehdration of the "od.In their oQn right, the!e $ain*Yiller! analge!ic!G can ca#!e fatal !idee[ect!, a$art from the damage that i! ca#!ed" the ongoing dehdration that i! tem$oraril !ilenced Qitho#tremo&ing the root ca#!e of the!e $ain!Zla de!hidratación.er often, the!e analge!ic! ca#!e ga!trointe!tinal"leeding.A feQ tho#!and $eo$le die e&er earfrom thi! com$lication of fre(#ent analge!ic intaYe. It i! noQ 5??=G clearthat o&er*the*co#nter $ain*Yiller! can in!ome $eo$le ca#!e li&er and Yidne damage and act a! $eo$le Yiller!.

 2he !cientic "acYgro#nd for the a"o&e &ieQ! i! alread a&aila"le to!cienti!t! in $ain re!earch. 2hi! "rief i!intended to "r#!h a!ide the $rofe!!ional re!i!tance of the AMA and theNIH Qhich are aQare of m nding! andha&e, contrar to their oath and o"ligation! to the !ociet, ref#!ed to$ro$agate it to the #ltimate "enet of the $#"lic. 2hi! 7&ieQ !hift7 on the role of Qater in the "od can QorY Qonder! inthe f#t#re $ractice of clinical medicineZQhichi! Qh the!e $rofe!!ional "odie!, Qho gain " the $er$et#ation of their$a!t ignorance, ha&e not engaged in thedi!!emination of information a"o#t the $ro"lem! a!!ociated Qith lacY of 

!#\cient Qater in the h#man "od. 2he moment medical $rofe!!ional! ado$t thi! $aradigm !hift, the$re!ent form of 7ignorance of the h#man "od"a!ed medical $ractice7 Qill tran!form to a tho#ghtf#l, $re&enti&ea$$roach to health care. More im$ortantl, !im$le$h!iolog*"a!ed c#re! to earl di!ea!e emergence Qill "ecomea&aila"le Qell "efore irre&er!i"le damage cane!ta"li!h.DO0/E/2IC /AINA neQl recognied emergenc thir!t !ignal of the h#man "od.D!$e$tic $ain i! the mo!t im$ortant !ignal for the h#man "od. It

denote! dehdration. It i! a thir!t !ignal of thec#er$o.It can occ#r in the &er o#ng, a! Qell a! in older $eo$le.Chronicand $er!i!tentl increa!ing dehdration i!the root ca#!e of almo!t all c#rrentl enco#ntered major di!ea!e! of theh#man "od.1f the d!$e$tic $ain!, that of ga!triti!, d#odeniti!, and heart"#rn!ho#ld "e treated Qith an increa!e in Qater intaYe

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!olo.Shen there i! a!!ociated #lceration, attention to the dail diet toenhance the rate of re$air of the #lcer !ite

!e hace nece!ario.According to /rofe!!or HoQard 0$iro of Oale Uni&er!it, it i! generall#nder!tood that 5; $ercent of tho!e Qithd!$e$!ia de&elo$ #lceration in their d#oden#m after !i% ear!, 8>$ercent after 5> ear! and => $ercent after ;<ao.It i! the d!$e$tic $ain that i! of !ignicance, altho#gh the conditionde&elo$! im$ortance once the #lcerationi! &ieQed thro#gh the endo!co$ic e%amination. It !eem! that medical$ractice i! "ecoming more and more a &i!#alloriented di!ci$line rather than the $erce$ti&e and tho#ght*"a!ed art thatit Qa! at one time.

It i! the $ain a!!ociated Qith the!e di[erentl cla!!ied condition! thatforce! the $er!on to con!#lt a medical$racticante.It i! thi! $ain that i! noQ getting m#ch attention e&en tho#ghman di[erent jargon! are attached to thelocal condition! !een thro#gh the endo!co$e. 2he common factor i! thed!$e$tic $ain. 2he local ti!!#e change i!the de!cri$ti&e e%$lanation for the change! "ro#ght a"o#t " the "a!iccommon factor, namel the initiatingla de!hidratación.HoQ am I a"le to maYe !#ch claim! I ha&e treated Qith onl Qater Qello&er 8>>> $er!on! Qith d!$e$tic $ain Qho

had other di!ting#i!hing characteri!tic! to cla!!if them according totho!e jargon!. 2he all re!$onded to anincrea!e in their Qater intaYe, and their clinical $ro"lem! a!!ociated Qiththe $ain di!a$$eared. 2he re$ort of mneQ Qa of treating d!$e$tic $ain Qith Qater Qa! $#"li!hed a! theeditorial article in the Jo#rnal of Clinicala!troenterolog in J#ne of 5?:8.At a certain thre!hold of dehdration, Qhen the "od #rgentl call! forQater, nothing el!e can !#"!tit#te. nomedication other than Qater i! e[ecti&e. 1ne of the man $atient! Itreated Qith Qater !tand! o#t and $ro&e! thi!

hecho.He Qa! a o#ng man in hi! middle tQentie!.He had !#[ered from$e$tic #lcer di!ea!e for a n#m"er of ear!"efore the cri!i! time, Qhen I met him. He had the #!#al diagno!tic$roced#re! $erformed on him and recei&ed thela"el of 7d#odenal #lcer.7 He had "een gi&en antacid! and "rand namecimetidine medication!.Cimetidine i! a form of &er !trong medication that "locY! the action of hi!tamine on it! 7;nd7 t$e recei&er $oint!,

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generall YnoQn a! 7rece$tor!7 in the "od, and, in thi! ca!e, YnoQn a!hi!tamine ; or H rece$tor. It j#!t ha$$en!

that !ome cell! in the !tomach that $rod#ce the acid are !en!iti&e to thi!medication. HoQe&er, man, man othercell! in the "od that do not $rod#ce acid are al!o !en!iti&e to thi!"locYing action of the medication. 2hat i! Qh thi!medication ha! man other !ide e[ect!, incl#ding im$otence in theo#ngG and ha! $ro&en e%tremel dangero#! inthe chronicall dehdrated older age gro#$. 2he r!t time I !et ee! on the o#ng man Qa! at ele&en one e&ening inthe !#mmer of 5?:>. He Qa! in !#ch $ainthat he Qa! almo!t !emicon!cio#!.He Qa! ling folded in the fetal$o!ition on the oor of hi! room. era

groaning !teadil, #naQare of hi! en&ironment and the Qorried $eo$learo#nd him. Shen I talYed to him, he did notre!$ond. He Qa! not comm#nicating Qith tho!e aro#nd him. I had to!haYe him to get a re!$on!e.I a!Yed him Qhat Qa! the matter. He groaned, 7M #lcer i! Yilling me.7 Ia!Yed him hoQ long he had had the $ain.He !aid hi! $ain !tarted at one in the afternoon, immediatel after hi!l#nch. 2he $ain increa!ed in inten!it a! time$a!!ed. I a!Yed him Qhat he had done to get relief and if he had taYenan medication. He re$lied that he had taYenthree ta"let! of cimetidine and one Qhole "ottle of antacid d#ring thi!

time. He indicated that he got a"!ol#tel norelief, e&en Qith thi! amo#nt of medication, in the ten ho#r! !ince hi!$ain r!t !tarted.Shen !o m#ch medication cannot relie&e the $ain of $e$tic #lcerdi!ea!e, one a#tomaticall "ecome! !#!$icio#! of7ac#te a"domen,7 !omething that might $o!!i"l need !#rgicale%$loration.Ma"e hi! #lcer had $erforated t#&e!een and a!!i!ted in the o$eration of $atient! Qith $erforated $e$tic#lcer!. 2ho!e $er!on! Qere de&a!tatedZ&erm#ch liYe the o#ng man "efore me. 2he te!t i! &er !im$le !#ch$atient! de&elo$ a &er rigid a"dominal Qall,

almo!t liYe a Qooden "oard. I felt for the rigidit of the Qall of thea"domen in thi! o#ng man. Fort#natel, he hadnot $erforated. Hi! a"dominal Qall Qa! !oft, "#t tender from the $ain. HeQa! l#cY he had not $erforated, altho#ghif he had contin#ed liYe thi!, the acid Qo#ld ha&e $#nched a holethro#gh hi! noQ inamed #lcer. 2he ar!enal of medication! in !#ch circ#m!tance! i! &er limited. 2hreecimetidine ta"let! of 8>> milligram! each

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and one f#ll "ottle of antacid co#ld not relie&e the $ain. 1ften, !#chca!e! Qo#ld end on the o$erating ta"le of a

Ynife*ha$$ !#rgeon. Beca#!e of m e%ten!i&e e%$erience Qith the $ain*relie&ing $ro$ert of Qater in d!$e$tic$ain!, I ga&e thi! man tQo f#ll gla!!e! of QaterZone $int.At r!t he Qa!rel#ctant to drinY the Qater. Le dije (#ehad taYen the #!#al medication! Qitho#t an re!#lt.He !ho#ld noQ tr7m medication7 for thi! di!ea!e. l no ten+aelección.He Qa! in !e&ere $ain and did not YnoQ Qhat to do a"o#t it.I !atin a corner and o"!er&ed him for a feQmin#to!.I had to lea&e the room, and Qhen I ret#rned in a"o#t fteen min#te!,hi! $ain had "ecome le!! !e&ere and hi!

groan! !to$$ed. I ga&e him another f#ll ,gla!! of QaterZhalf a $int. In afeQ min#te!, hi! $ain di!a$$earedcom$letel and he !tarted taYing notice of the $eo$le aro#nd him. He!at #$ and "egan to mo&e toQard the Qall ofla ha"itación.Sith hi! "acY to the Qall, he !tarted to cond#ctcon&er!ation! Qith hi! &i!itor! Qho Qere noQ more!#r$ri!ed than he at the !#dden tran!formation that three gla!!e! of Qater had "ro#ght a"o#t For 5> ho#r!, thi!man had !#[ered from $ain and taYen the mo!t $otent and ad&ancedmedicine! for the treatment of $e$tic #lcerdi!ea!e Qitho#t an relief. NoQ, three gla!!e! of Qater had $rod#ced an

o"&io#! and a"!ol#te relief in a"o#t ;>min#to!.If o# refer to Fig#re = on $age ;8 and com$are the !tatement! in themodel on $ain Qith the e%$erience of thea"o&e $atient, o# Qill recognie the "rain com$onent to the inten!it of !ignaling thir!t in the "od. After a certainthre!hold, local $ainYiller! Qill not "e e[ecti&e. 2he antacid and HI"locYing agent cimetidine did not $rod#ce e&en ared#ction in the $ain felt " the o#ng man. It Qa! Qater alone thatregi!tered the right me!!age Qith the "rain toa"ort it! call for Qater, !ince there Qa! noQ an #nmi!taYa"le !ignal of it!

ade(#ate $re!ence in the "od. lo mi!momode of $ain regi!tration i! o$erati&e in other region! that !ignaldehdration in an $artic#lar indi&id#al. La! $er!ona! conrhe#matoid joint $ain !ho#ld "e aQare of thi! $artic#lar $henomenon of $ain regi!tration at the "rain Qhen there i!!e&ere dehdration.I had another occa!ion to te!t Qhether the a"dominal $ain regi!trationfor dehdration Qa! time*de$endent or Qater*

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&ol#me*de$endent. 2hi! time, a man Qa! carried " tQo other $er!on!into the clinic Qhere I Qa! QorYing at the

tiem$o.2he $atient co#ld not QalYhe Qa! lifted from #nder hi! arm! "tQo other $er!on!.He, too, Qa! a $e$tic #lcer$atient in e%tremel !e&ere #$$er a"dominal or d!$e$tic $ain. Aftere%amination to !ee that he had not $erforated,I ga&e the $atient one f#ll gla!! of Qater e&er ho#r. He did not achie&etotal relief in ;> min#te!, or e&en one ho#rand ;> min#te!. He reco&ered after he had taYen three gla!!e! of Qater.1n the a&erage, it taYe! le!! !e&ere ca!e!a"o#t eight min#te! to achie&e total $ain relief.It ha! "een !hoQn e%$erimentall that, Qhen Qe drinY one gla!! of Qater, it immediatel $a!!e! into the inte!tine

and i! a"!or"ed. HoQe&er, Qithin one half*ho#r, almo!t the !ameamo#nt of Qater i! !ecreted into the !tomachthro#gh it! gland#lar laer in the m#co!a. It !Qell! from #nderneath andget! into the !tomach, read to "e #!ed forfood "reaYdoQn.2he act of dige!tion of !olid food! de$end! on the$re!ence of co$io#! amo#nt! of Qater. laacid i! $o#red on the food, enme! are acti&ated, and the food i!"roYen doQn into a homogenied #id !tate thatcan $a!! into the inte!tine for the ne%t $ha!e of dige!tion. 2he m#c#! co&er! the gland!T laer of the m#co!a, Qhich i! theinnermo!t laer of the !tr#ct#re of the !tomach !ee

La Fig#ra 9G.M#c#! con!i!t! of ?: $ercent Qater and tQo $ercent the$h!ical 7!ca[olding7 that tra$! Qater. En e!te7Qater laer7 called m#c#!, a nat#ral "#[er !tate i! e!ta"li!hed. 2hecell! "eloQ !ecrete !odi#m "icar"onate that i!tra$$ed in the Qater laer. A! the acid from the !tomach trie! to gothro#gh thi! $rotecti&e laer, the "icar"onatene#tralie! it. 2he o#tcome of thi! action i! a greater $rod#ction of !alt !odi#m fromthe "icar"onate and chlorine from the acidG. 2oo m#ch !alt alter! the Qater*holding $ro$ertie! of the 7!ca[olding7material of m#c#!. 2oo m#ch acid

ne#traliation and !alt de$o!it! in thi! m#c#! laer Qo#ld maYe it le!!homogeneo#! and !ticY and Qo#ld alloQ theacid to get to the m#co!al laer, ca#!ing $ain. 2he nat#ral de!ign in the re!ection of Qater thro#gh the m#c#! laer!eem! to "e the $roce!! of 7"acY*Qa!hing7 them#c#! laer and getting rid of the !alt de$o!it!. 2hi! i! a mo!t e\cientde!ign for rehdrating the m#c#! laer from

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the "ottom Qhen neQ m#c#! i! al!o !ecreted. 2hi! refre!hed, thicYenedand !ticY m#c#! "arrier i! the nat#ral

$rotecti&e !hield again!t the acid in the !tomach. Nat#rall, thee\cienc of thi! !hield de$end! on a reg#lar intaYeof Qater, $artic#larl "efore the intaYe of di[erent !olid food! that Qo#ld!tim#late the $rod#ction of acid from thegland! in the !tomach Qall. 2h#!, Qater $ro&ide! the onl nat#ral$rotection again!t the acid in the !tomach, from"a!e #$Qard. Antacid! are de!igned to attach to the acid in the !tomachit!elfZ an ine\cient $rotection.Se !ho#ld "egin to realie that in the !ame Qa Qe ha&e a 7h#nger$ain7 !ignal, Qe al!o ha&e a 7thir!t $ain7 !ignalin the "od. It i! #nfort#nate the call it 7d!$e$!ia7 and treat it Qith all

!ort! of medication! #ntil there i! locald#odenal or !tomach ti!!#e damage from the meta"olic com$lication! of dehdration. 2he #!e of antacid! for therelief of thi! $ain i! generall the acce$ted form of treatment. 2he!e!#"!tance! are non*$re!cri$tion !loQ $oi!on!that one can "# e&en in the !#$ermarYet!.0ignicant re!earch cond#cted in 0Qeden ha! !hoQn that the o#tcome i!the !ame in tho!e Qho do not ha&e anact#al #lcer and et ha&e the cla!!ical d!$e$tic $ain, Qhether or notthe #!e a $lace"o, an antacid, or e&en theagent that "locY! the action of hi!tamine. In other Qord!, neither antacid

nor the !tronger medication are all thatefecti&a.It i! at thi! !tage of "od $h!iolog, noQ generating !ignal! of dehdration, that one !ho#ld "e $r#dentand refrain from the #!e of an form of medication.Sater i! mo!t $ro"a"l the onl e[ecti&e !#"!tance to gi&e relief. Afterall Qater, and onl Qater, i! Qhat the "odQant!, need!, and i! calling for. If Qe !earch acc#ratel for other !ign!,there Qo#ld "e more indicator! ofla de!hidratación.Do not imagine that d!$e$tic $ain i! the indicator of an i!olated and localied $henomenon. En c#al(#ierca!e, d!$e$tic $ain i! a !ignal of dehdrationZa thir!t !ignalZof the

"od, e&en if there i! an a!!ociated #lcer. !iQater i! taYen and it relie&e! o#r $ain, Qith ade(#ate food intaYe the#lcer i! "o#nd to re$air it!elf in d#e time.It i! noQ !aid that #lcer! are the re!#lt of infection!. M re!earchedo$inion i! that the &ariet of c#r&ed "acteria,"lamed for ca#!ing #lceration!, are commen!al!, "acteria that nat#ralldQell in the inte!tine!. 2he ma taYe an

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#nfair ad&antage from the imm#ne !!tem !#$$re!!ion that i! the directo#tcome of dehdration. Oo# !ee, the

normal inte!tinal "acteria coha"itate Qith #! and $rod#ce m#ch of the&itamin! needed " the "od. 2he contri"#teto o#r Qell*"eing Qhen Qe are !trong. In dehdration, $artic#larl at the!ite of the &al&e "etQeen the !tomach andthe d#oden#m man hi!tamine $rod#cing ner&e! e%i!t. 2hi! $artic#larc#r&ed "acteri#m "enet! from the groQthhormone e[ect! of hi!tamine. at the !ame time that the!e ner&e! arere!tricti&el monitoring the rate of oQ of the!trongl acidic content of the !tomach into the inte!tine. In an ca!e, notall #lcer !ite! !hoQ the $re!ence of7helico"acter!.7 Al!o, an innite n#m"er of $eo$le ma ha&e

helico"acter in their inte!tine! and not !#[er from#lcer!Antacid! that contain al#min#m are dangero#!. 2he !ho#ld not "efreel #!ed for a condition that Qill re!$ond to anincrea!e in Qater intaYe. E%ce!!i&e al#min#m in circ#lation ha! "een&er !trongl im$licated a! a $reci$itatingfactor on to$ of other con!ideration! in Alheimer*t$e di!ea!e. It i!im$erati&e to #nder!tand thi! relation!hi$"etQeen taYing al#min#m*containing antacid! for a long $eriod of timeand it! $o!!i"le acc#m#lati&e to%ic !idee[ect of "rain damage in AlheimerT! di!ea!e. No amo#nt of genetic

!t#d Qill #ndo the to%ic !ide e[ect of a metal#!ed in medication! to deal Qith a !im$le !ignal of thir!t #nder a Qrong$aradigm. Mo!t antacid! contain "etQeen59>*@>> milligram! of al#min#m in e&er !$oonf#l of the li(#id, or ineach ta"let that i! cheQed. 2he i!land of #am ha! m#ch al#min#m ore in it! !oil normall the ca!efor !ome region! in the Se!tern /acicZ#am i!land, Kii $enin!#la in Ja$an, Se!tern NeQ #inea, and other!G. 2he drinYing Qater of the i!land Qa!hea&il contaminated Qith al#min#m. D#ring the time thi!contamination Qa! not recognied and remained in the

drinYing Qater, a di!ea!e !imilar to Alheimer dementia Qa! $re&alenton the i!land. E&en the o#nger $eo$le onthe i!land !eemed to !#[er from the di!ea!e. A n#m"er of ear! ago thi!$ro"lem Qa! recognied and the Qater$#ried. It ha! "een noticed that the o#nger $eo$le !eem not to "ea]icted an more. It i! noQ taYen for grantedthat it Qa! the al#min#m to%icit in the drinYing Qater that ca#!ed anAlheimer*t$e of dementia on the i!land of

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#am.Hi!tamine "locYing agent! are al!o not !#ita"le for long*term #!e.2he

ha&e man !ide e[ect!. E!to! incl#endiine!! and conf#!ion !tate! in the elderl. Enlarged "rea!t! a$$ear inmen after a feQ QeeY! of taYing thi!la medicación.LoQ !$erm co#nt in !ome male $atient! and lo!! of li"idoha&e al!o "een noted.N#r!ing mother! or$regnant Qomen !ho#ld not #!e thi! t$e of medication to treat thethir!t !ignal! of the "odZthe childT! and themotherT!. Brain ca$illarie! re!$ond to dehdration " dilating if hi!tamine !tim#late! them. 2he!e antihi!tamine! Qill"locY the ca$illar dilating action of hi!tamine Qhen the "rain ha! tota"#late more information than normal, !#ch a!

Qhen #nder the $re!!#re of !tre!!. 2he "rain Qill get le!! "lood !#$$lQhen antihi!tamine! are #!ed for d!$e$tic$ain treatment. 2he $rimar ca#!e of AlheimerT! di!ea!e i! chronic dehdration of the"od. In m o$inion, "rain cell dehdration i!the $rimar ca#!e of Alheimer di!ea!e. Al#min#m to%icit i! a!econdar com$lication of dehdration in area! ofthe Qorld Qith com$arati&el al#min#m*free Qater. Ca#tion4 In thetechnicall ad&anced Se!tern !ocietie!al#min#m !#l$hate i! at time! #!ed in the $roce!! of Qater $#ricationfor deli&er into the cit Qater !#$$lie!. en

$rolonged dehdration, the "rain cell! "egin to !hrinY.Imagine a $l#mgrad#all t#rning into a $r#ne. De!afort#nadamente,in a dehdrated !tate, man, man f#nction! of "rain cell! "egin to getlo!t, !#ch a! the tran!$ort !!tem thatdeli&er! ne#rotran!mitter! to ner&e ending!. 1ne of m medical friend!tooY thi! information to heart and !tartedtreating hi! "rother Qho ha! AlheimerT! di!ea!e " forcing him to taYemore Qater e&er da. Hi! "rother ha!"eg#n to reco&er hi! memor, !o m#ch !o that he can noQ folloQcon&er!ation and not fre(#entl re$eat him!elf. 2he im$ro&ement "ecame noticea"le in a matter of QeeY!.

It !ho#ld "e recognied that altho#gh $ain i! localied to the region of the !tomach, the dehdration i! e!ta"li!hed allo&er the "od. Not recogniing d!$e$tic $ain to "e a thir!t !ignal callingfor Qater Qill, later in Me, ca#!e the h#man"od man irre&er!i"le $ro"lem!. 1f co#r!e, a !tomach t#mor co#ldca#!e a !imilar $ain. HoQe&er, that $ain Qill notdi!a$$ear Qith Qater. It Qill contin#e to rec#r. In ca!e there are re$eated$ain! e&en Qhen Qater intaYe ha! "een

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reg#lated for a n#m"er of da!, it Qo#ld "e $r#dent to con!#lt a$h!ician for a!!e!!ment of the condition. 0i el

$ain i! from ga!triti! and d#odeniti!, or e&en $e$tic #lceration!, reg#larintaYe of Qater i! a m#!t in the dail ro#tineand dietar adj#!tment! for the treatment of the condition!.C1LI2I0 /AINColiti! $ain, felt in the loQer left $art of the a"domen, !ho#ld initiall "e&ieQed a! another thir!t !ignal for the h#manc#er$o.It i! often a!!ociated Qith con!ti$ation, it!elf ca#!ed "$er!i!tent dehdration.1ne of the main f#nction! of the large inte!tine i! the $roce!! of taYingQater o#t of the e%crement! !o that toom#ch of it i! not lo!t in the Qa!te matter after food dige!tion. Shen

there i! dehdration, the re!id#e i! nat#rallde&oid of the normal amo#nt of Qater nece!!ar for it! ea!ier $a!!age.Al!o, " !loQing doQn the oQ and f#rther!(#eeing the content, e&en the nal dro$! of Qater Qill "e draQn aQafrom the !olid re!id#e in the large g#t. /or lo tanto,con!ti$ation Qill "ecome a com$lication of dehdration in the "od. Sithadded food intaYe, more !olid Qa!te Qill "e$acYed into the inte!tine and increa!e the "#rden for $a!!age of it!hardened Qa!te content. E!te $roce!o !eca#!e $ain. Coliti! $ain !ho#ld initiall "e con!idered a! a thir!t !ignal of the "od. Sith ade(#ate Qater intaYe, the

left loQer a"dominal $ain that i! a!!ociated Qith con!ti$ation Qilldi!a$$ear. Eating an a$$le, a $ear, or an orange inthe e&ening! Qill hel$ red#ce con!ti$ation in the ne%t da.FAL0E A//ENDICI2I0 /AINA !e&ere $ain can !ometime! a$$ear on the right loQer a"dominalregion. It can mimic an inammation of thea$$endi% and $re!ent !ome !imilarit to the $ain of earl a$$endiciti!.1ther di!ting#i!hing characteri!tic! are not!een there i! no ri!e in "od tem$erat#re there i! no g#arding andtenderne!! in the a"dominal Qall and no feelingof na#!ea. 1ne or tQo gla!!e! of Qater Qill relie&e thi! loQer right

a"dominal $ain. 1ne gla!! of Qater can !er&e a!a diagno!tic tool in thi! $artic#lar condition.HIA2U0 HERNIA Oo# often come acro!! the cla!!ical d!$e$tic $ain that the doctor ha!diagno!ed a! hiat#! hernia hiatal herniaG.Hiat#! hernia mean! di!$lacement of the #$$er $art of the !tomachthro#gh the ga$ of the dia$hragm the

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e!o$hageal hiat#!G into the che!t ca&it. 2hi! Qo#ld "e an #nnat#rallocation for the !tomach to "e in. Sith a $art of

the !tomach in the che!t, food dige!tion "ecome! $ainf#l. 2he acid inthe !tomach Qill freel $#!h #$Qard andto#ch the #n$rotected Qall of the e!o$hag#!. It ca#!e! the $ain of heart"#rn.Normall, the content of the #$$er $art of the !tomach i! !ealed o[ andcannot $a!! #$Qard into the e!o$hag#!Qhen food i! "eing dige!ted. 2he normal direction of inte!tinalcontraction! i! doQnQard, from the mo#th to therect#m. F#rthermore, there are tQo &al&e! that $re&ent the reg#rgitationof food #$Qard. 1ne &al&e i! located in theQall of the tract "etQeen the e!o$hag#! and the !tomach. 2hi! &al&e

onl rela%e! Qhen food i! going into thee!tómago. 2he other tra$ &al&e i! located o#t!ide of the tract in the dia$hragm,Qhere the e!o$hag#! $a!!e! thro#gh it! hiat#!to join the !tomach. 2hi! 7tra$ &al&e7 i! !nchronied to rela% e&er timethe food that i! "eing !QalloQed in thee!o$hag#! ha! to $a!! thro#gh it. At other time!, it i! tight and doe! not$ermit the content of the !tomach to $a!!hacia arri"a.2hi! i! the normal !tate of a[air! for the tQo 7&al&e!7 that$re&ent the $a!!age of food from re&er!ingdirection and $a!!ing #$Qard.

 2he inte!tinal tract, from the mo#th to the rect#m, i! a long t#"e.Di[erent $art! of it ha&e de&elo$ed !$ecial$h!ical and f#nctional attri"#te! to maYe the $roce!! of food dige!tionand the e&ac#ation of it! Qa!te $rod#ct! aQell*integrated and !mooth o$eration. 2here are man, man localhormone! that maYe thi! o$eration $o!!i"le.Local hormone! are chemical me!!enger! that !ignal and time the ne%t!tage of the $roce!! to 7YicY in.7 ello!ca#!e the nece!!ar enme! to "e !ecreted to f#rther the "reaYdoQnand !#"!e(#ent a"!or$tion of the acti&ematerial! in food.

Earl in the $roce!! of dige!tion, acid i! !ecreted in the !tomach toacti&ate the enme! and hel$ in the "reaYdoQnof !olid $rotein! !#ch a! meat and hard*to*dige!t food!. Normall, theli(#eed "#t highl acidic content of the!tomach i! $#m$ed into the r!t $art of the inte!tine.2here i! a &al&e"etQeen the !tomach and the inte!tine. e!called the 7$loric &al&e.7 2he o$eration of thi! &al&e i! reg#lated " theme!!age !!tem from either !ide of the

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7tract.7 It i! one thing for the !tomach to Qi!h to em$t it! content intothe inte!tine it i! another thing for the

inte!tine to "e read to recei&e thi! highl corro!i&e and acidic ga!triccontent 2he $ancrea! i! a gland that !ecrete! in!#lin to reg#late "lood !#gar. Ital!o $o#r! !ome e!!ential dige!ti&eenme! into the inte!tine. 2he $ancrea! ha!, at the !ame time, the$h!iological re!$on!i"ilit of rendering theinte!tinal en&ironment alYaline "efore the acid from the !tomach canreach the inte!tine. El m)! im$ortantef#nction of the $ancrea! i! it! con!tant role of man#fact#ring and!ecreting of a 7Qater "icar"onate !ol#tion7ZthealYaline !ol#tion that Qill ne#tralie the acid that enter! the inte!tine. 2o

man#fact#re the Qater "icar"onate!ol#tion, the $ancrea! Qill need m#ch Qater from the circ#lation. Indehdration, thi! $roce!! i! not &er e\cient.For thi! rea!on, the $loric &al&e Qill not recei&e the dear !ignal! to o$enand alloQ !tomach acid to $o#r into theinte!tino.2hi! i! the r!t !te$ in the $rod#ction of the d!$e$tic $ain, theinitial thir!t indicator of the h#man "od.Shen Qe drinY Qater, de$ending on the &ol#me of Qater that enter! the!tomach, a hormonene#rotran!mittercalled 7motilin7 i! !ecreted. 2he more Qater Qe drinY, the more motilin i!$rod#ced " the inte!tinal tract and can "e

mea!#red in "lood circ#lation. 2he e[ect of motilin on the inte!tinaltract, a! it! name im$lie!, i! to $rod#ce rhthmiccontraction! of the inte!tine!Z $eri!tal!i!Zfrom it! #$$er $art! to it!loQer end. /art of thi! action Qo#ld in&ol&e thetimel o$ening and clo!ing of the &al&e! that are in the Qa of oQ of the inte!tinal content. 2h#!, Qhen there i! eno#gh Qater in the "od for all the dige!ti&e$roce!!e! that de$end on the a&aila"ilit of Qater,the $ancrea! Qill $rod#ce it! Qater "icar"onate !ol#tion to $re$are the#$$er $art of the inte!tinal tract to recei&ethe acidic content of the !tomach. Under !#ch ideal circ#m!tance!, the

$loric &al&e i! al!o alloQed to o$en for thee&ac#ation of the content of the !tomach. Motilin ha! a major7tran!mi!!ion7 role in coordinating thi! action. Motilini! a !atiet hormone !ecreted Qhen Qater e%tend! the !tomach Qall. 2he $ro"lem "egin! Qhen there i! not eno#gh Qater in the "od forthe!e dige!ti&e e&ent! to taYe $lace in acoordinated manner. In no Qa Qill the !!tem alloQ the corro!i&e acidcontent of the !tomach to reach the inte!tine

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if the mechani!m to ne#tralie it i! not e[ecti&e. 2he damage Qo#ld "eirre$ara"le. 2he Qall! of the inte!tine! do

not $o!!e!! the !ame $rotecti&e laer again!t acid that i! a&aila"le tothe !tomach. 2he r!t thing that ha$$en! i!the re&er!al of the !trength of contraction in the &al&e! on either !ide of the !tomach. 2he $loric &al&e Qill con!trictm)! m)!. 2he ring &al&e "etQeen the e!o$hag#! and the !tomach and thee%ternal 7&al&e7 of the dia$hragm Qill "ecomemore rela%ed. Initiall, !ome of the acid ma oQ into the e!o$hag#!Qhen the $er!on i! ling doQn and $rod#ce at$e of $ain that i! often called heart"#rn.In !ome, the la%it of the 7&al&e7 in the dia$hragm ma "e !#ch that a

$ortion of the !tomach ma $a!! thro#gh itinto the che!t and achie&e the title of hiat#! hernia. Shen the &al&e!re&er!e their mode of o$eration for the normaloQ of the !tomach content, in e[ect the are $re$aring for anothere&ent#al and #na&oida"le o#tcome4 thee&ac#ation of the !tomach content thro#gh the mo#th. If the !tomachcontent cannot go into the inte!tine and itcannot indenitel remain in the !tomach, there i! onl one other Qao#tZthro#gh the mo#th. For thi! action totaYe $lace, the inte!tinal tract i! ca$a"le of re&er!ing the direction of it!contraction!. 2he re&er!al of the

contraction! i! called 7anti*$eri!tal!i!.71ne of the mo!t mi!#nder!tood and #$!etting condition! that i! acom$lication of !e&ere dehdration i! "#limia./eo$le Qho !#[er from "#limiaZthe mo!t nota"le of them i! /rince!!Diana, Qho ha! "een de&a!tated Qith thi!$ro"lem and Qho!e marriage to /rince Charle! Qa! de!troed "eca#!eof thi! anti!ocial $ro"lemZ!#[er fromcon!tant 7h#nger.7 Shen the eat, the cannot retain the food and ha&ean in!tant #ncontrolla"le #rge to &omitZth#!, their anti!ocial life*!tle. In the!e $eo$le, their !en!ation of 7h#nger7 i!, in fact, an indicator of thir!t, and their

#rge to &omit i! the $rotection mechani!m that i! e%$lained a"o&e. If "#limic! "egin to rehdrate their "od Qell anddrinY Qater "efore their food, thi! $ro"lem Qill di!a$$ear.In m o$inion, "eca#!e of the re$eated corro!i&e e[ect of thereg#rgitating acid on the #n$rotected e!o$hagealti!!#e, there i! a !trong relation!hi$ "etQeen heart"#rn of earl life ande&ent#al cancer of the loQer end of thee!ófago.

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D!$e$tic $ain, no matter Qhat other $athological la"el i! attached to it,!ho#ld "e treated " reg#lar intaYe of Qater.

 2he c#rrent treatment $ractice and the #!e of antacid! and hi!tamine*"locYing agent! i! not to the "enet of achronicall dehdrated $er!on Qho!e "od ha! re!orted to cring forQater.A.B.i! her!elf engaged in the $romotion of alternati&e medicine.0he i!&er !trongl into chelation thera$. ella tienecom$iled other $eo$leT! information and Qritten a $o$#lar "ooY onchelation. HoQe&er, !he had her!elf !#[ered forman ear! from e%cr#ciating $ain! from her hiat#! hernia. Herh#!"and, him!elf a mo!t delightf#l a#thor, tell! methat A.B. co#ld hardl !it thro#gh a meal and not !#[er from !#ch !e&ere

$ain! a! to "e a"le to com$lete her foodand enjo !itting doQn for a chat. At time!, the Qo#ld ha&e to lea&e there!ta#rant "eca#!e the $ain Qo#ld notalloQ her e&en a !hort re!$ite to ni!h her meal.A.B.tell! me !he hardl dranY an Qater.1nl after H.B.had " chancecome acro!! m "ooY and read it, did thenall #nder!tand A.B.T! $ro"lem. 0he "egan drinYing Qater. A! !heincrea!ed her Qater intaYe, !he noticed her$ain Qa! le!! !e&ere. In a matter of da! it di!a$$eared com$letel,ne&er to come "acY. 2he h#!"and and QifenoQ enjo going o#t to eat. M Qife and I ate Qith them a feQ time!. It

a$$ear! her hiatal hernia and it! $ain areancient hi!tor. It i! intere!ting to note that e&en chelation, her $ettreatment $roced#re for !o man condition!,co#ld not hel$ her. It !ho#ld "ecome clear that the hidden merit! of chelation thera$ in mo!t ca!e! i! in it! re(#iredhigh*&ol#me Qater intaYe d#ring the act#al treatment $roced#re.HoQe&er in the $a!t, increa!ed Qater intaYe Qa!not a ro#tine recommendation for in*"etQeen the treatment !e!!ion!.B#t, a! a re!#lt of m talY! and re&ieQ! of m"ooY in their fa&orite Jo#rnal of 2oQn!end Letter for Doctor!, mo!t$ractitioner! of 7Alternati&e Medicine7 are noQ

recommending increa!ed Qater intaYe " their $atient!. Chelationthera$ i! mo!t e[ecti&e in e%tracting to%ic metal!o#t of the "od.In 0#mmar4 D!$e$tic $ain i! a thir!t !ignal a!!ociated Qith chronic or!e&ere dehdration in the h#man "od. loco#ld al!o e%i!t in conj#nction Qith other thir!t $ain! of the "od. 2aYe alooY at Mr. Lig#oriT! letter on $age ?;. A!

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o# can !ee, Mr. Lig#ori had "oth the $ain of hiatal hernia and al!oanginal $ain. Sith increa!ed Qater intaYe, one

$ain ha! di!a$$eared and the other ha! dimini!hed !ignicantl in onlone QeeY of increa!ed Qater intaYe. altime of the nal Qriting of thi! $age, hi! $ain !eem! to ha&e com$letelcleared #$.72he Qor!t !in toQard o#r felloQ creat#re! i! not to hate them, "#t to "eindi[erent to them4 thatT! the e!!ence ofinh#manit.7 eorge Bernard 0hoQ, 5:?<RHEUMA21ID AR2HRI2I0 /AIN0A"o#t 9> million American! !#[er from !ome form of arthriti!, 8> million$eo$le !#[er from loQ "acY $ain, million!!#[er from arthritic necY $ain!, and ;>>,>>> children are a[ected " the

 j#&enile form of arthriti!. 1nce an of the!econdition! e!ta"li!he! in an indi&id#al, it "ecome! a !entence for!#[ering d#ring the re!t of the indi&id#alT! lifeZ#nle!! the !im$licit of the root*ca#!e of the $ro"lem i! f#ll #nder!tood.Initiall, rhe#matoid arthritic joint! and their $ain are to "e &ieQed a!indicator! of Qater decienc in the a[ected joint cartilage !#rface!. Arthriti! $ain i! another of the regional thir!t!ignal! of the "od. In !ome arthriti! $ain!, !alt!hortage ma "e a contri"#ting factor. 2he cartilage !#rface! of "one! in a joint contain m#ch Qater. 2hel#"ricating $ro$ert of thi! 7held Qater7 i! #tilied

in the cartilage alloQing the tQo o$$o!ing !#rface! to freel glide o&erone another d#ring joint mo&ement.Sherea! the "one cell! are immer!ed in calci#m de$o!it!, the cartilagecell! are immer!ed in a matri% containingm#ch Qater.A! the cartilage !#rface! glide o&er one another, !ome e%$o!ed cell! dieand $eel aQa. NeQ cell! taYe their $lacefrom the groQing end! that are attached to the "one !#rface! on the tQo!ide!. In a Qell*hdrated cartilage, the rateof friction damage i! minimal.In a dehdrated cartilage, the rate of 7a"ra!i&e7 damage i! increa!ed. La relación

"etQeen the rate of regeneration of cartilage cell! to their 7a"ra!i&e$eel7 i! the inde% of joint e\cienc.Acti&el groQing "lood cell! in the "one marroQ taYe $riorit o&er thecartilage for the a&aila"le Qater that goe!thro#gh the "one !tr#ct#re. In the $roce!! of dilating the "lood &e!!el!to "ring more circ#lation to the area, it i!$o!!i"le that the "ranch that goe! thro#gh a tight hole in the "onecannot e%$and ade(#atel eno#gh to co$e la

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cell! that de$end on the!e &e!!el! for an increa!ed Qater and n#trient!#$$l are #nder a $h!icall im$o!ed

rationing control. Under !#ch circ#m!tance!, and #nle!! there i! "looddil#tion to carr more Qater, the 7!er#m7re(#irement! of the cartilage Qill ha&e to "e !ati!ed from the "lood&e!!el! that feed the ca$!#le of the joint. laner&e reg#lated !h#nting mechani!m! to all the joint!G al!o $rod#ce!ignal! of $ain.Initiall, thi! $ain i! an indication that the joint i! not f#ll $re$ared toend#re $re!!#re #ntil it i! f#ll hdrated. e!tet$e of $ain ha! to "e treated Qith a reg#lar increa!e in Qater intaYe to$rod#ce !ome dil#tion of "lood that i!circ#lating to the area #ntil the cartilage i! f#ll hdrated and re$aired

from it! "a!e attachment to the "oneZthenormal "one ro#te of !er#m di[#!ion to the cartilage. A looY at Fig#re! @and < Qill hel$ maYe the $oint! clear.It i! m a!!#m$tion that the !Qelling and $ain in the ca$!#le of the jointi! an indication there i! dilation and edemafrom the &e!!el! that f#rni!h circ#lation to the ca$!#le of the joint. Joint!#rface! ha&e ner&e ending! that reg#lateall f#nction!. Shen the $lace a demand for more "lood circ#lation tothe area to $icY #$ Qater from the !er#m, thecom$en!ator &a!c#lar e%$an!ion in the ca$!#le i! !#$$o!ed to maYe #$for the ine\cienc of circ#lation from the

"one ro#te of !#$$l.Beca#!e dehdration in the joint !#rface! Qill e&ent#all ca#!e !e&eredamageZto the $oint of maYing the "one!#rface! "are and e%$o!ed #ntil o!teoarthriti! "ecome! e!ta"li!hedZtheti!!#e damage Qill trigger a mechani!mfor remodeling of the joint 2here are hormone*!ecreting cell! in theca$!#le of the joint. Shen there i! damage al!ofrom dehdrationG, inj#red ti!!#e ha! to "e re$aired. 2he!e 7localremodeling hormone!7 taYe o&er and re!tr#ct#rethe joint !#rface!. It !eem! that the cater to the line! of force and$re!!#re that the joint! ha&e to end#re.

Unfort#natel, the re$air $roce!! !eem! to $rod#ce a de&iation of the joint!. 2o a&oid !#ch di!g#rement, one!ho#ld taYe the &er initial $ain !erio#!l and "egin a !trict attention todail intaYe of Qater. Initiall, thi! $ain !ho#ld"e recognied a! a !ign of local dehdration. If it doe! not di!a$$earafter a feQ da! of Qater intaYe and re$eatedgentle "ending of the joint! to "ring more circ#lation to the area, one!ho#ld then con!#lt a $rofe!!ional $ractitioner

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de la medicina. Oo# ha&e nothing to lo!e and e&erthing to gain " recogniing the $ain

and the non*infectio#! inammation of arhe#matoid joint a! a thir!t !ignal in o#r "od. Oo# are $ro"a"l !hoQingother !ignal! for Qater !hortage in o#r"od, "#t thi! $artic#lar !ite i! indicating $redi!$o!ition to a more !e&erelocal damage.If Qe #nder!tand the "od to ha&e di\c#lt in recogniing it! thir!t!tate, it i! $o!!i"le that thi! loQer !tate ofalertne!! i! al!o inherita"le " a child. It i! $o!!i"le that dehdration in ara$idl groQing child might al!o indicate it!$re!ence " the $ain felt in the joint! a! Qell a! it can "e felt inheart"#rn. 2he mode of !ignal $rod#ction that Qo#ld

denote thir!t might nat#rall "e the !ame in the o#ng, a! Qell a! inolder $eo$le. It i! therefore recommended that j#&enile arthriti! !ho#ld al!o "e treated Qith an increa!e in dail QaterintaYe.A! o# can !ee, Dr. La#rence Malone, Qho!e letter i! $#"li!hed "eloQ, i!an e%$erienced medical doctor and aned#cador.Hi! o"!er&ation! on the e[ect of Qater in rhe#matoid joint$ain! in him!elf !hoQ! that o#r othercolleag#e! in the medical $rofe!!ion!ho#ld "egin to notice the medicinal &al#e! of Qater in di!ea!e$re&ention.

/o!t!cri$t 2he "ooY i! alread in it! $rinter!T hand!. A feQ recentl introd#cedcommercial "rand! of Qater, Qith !eemingl!cientic e%$lanation! a"o#t the !$ecic Qa the are 7man#fact#red,7ha&e $rom$ted me to #!e the onl a&aila"le!$ace on thi! $age to clarif the folloQing $oint!. 2he correcti&e $h!iologic e[ect! of ordinar 7ta$7 Qater in !ome of thecondition! e%$lained in thi! "ooY are "eingattri"#ted to !$eciall $re$ared "rand! of 7!tr#ct#red Qater7 that are$re!ented for !ale. A! I alread e%$lained,Qater ha! man $ro$ertie!. It ha! !$ecial characteri!tic! in the

mem"rane! and in!ide the cell! of the "od.HoQe&er, if Qe !im#late tho!e characteri!tic! o#t!ide the "od, it doe!not mean that Qater Qill $a!! into the cell! ofthe "od Qith the !ame characteri!tic!. In fact, the cell mem"rane lter!and !e$arate! Qater from it! !olid contentand free! it from other di!!ol&ed material! to man#fact#re free and#!ef#l acti&ator "efore it! $a!!age in!ide the

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c'l#la.It ha! de&elo$ed the !!tem that the Qater molec#le! ha&e to "ein 7!ingle le7 "efore the can go thro#gh the

mem"rana.Sater di[#!e! into the cell at the rate of 5> centimeter $er!econd.2he di!!ol&ed !#"!tance! !ta"ehind, and their entrance into the cell i! reg#lated " material*!$ecic,!o$hi!ticated tran!$ort !!tem!. E!ta e! la formathe "od !#r&i&e!. It create! it! oQn 7#niformit of $re!entation7 Qithcon!tantl changing en&ironmental factor!./lea!e do not "e im$re!!ed " title! and jargon!. Begin to thinY "eforeo# acce$t !eemingl !cientic !tatement!that are de!igned to !ell o# a $rod#ctEl dolor l#m"arIt !ho#ld "e a$$reciated that the !$inal joint!Zinter&erte"ral joint! and

their di!c !tr#ct#re!Zare de$endent ondi[erent hdra#lic $ro$ertie! of Qater !tored in the di!c core, a! Qell a!in the end $late cartilage co&ering the at!#rface! of the !$inal &erte"rae. In !$inal &erte"ral joint!, Qater i! notonl a l#"ricant for the contact !#rface!, it i!held in the di!c core Qithin the inter&erte"ral !$ace and !#$$ort! thecom$re!!ion Qeight of the #$$er $art of thec#er$o.F#ll <9 $ercent of the Qeight of the #$$er $art of the "od i!!#$$orted " the Qater &ol#me that i! !tored inthe di!c core ;9 $ercent i! !#$$orted " the "ro#! material! aro#ndthe di!c !ee Fig#re :G. 2he $rinci$le in the

de!ign of all joint! i! for Qater to act a! a l#"ricating agent, a! Qell a!"earing the force $rod#ced " Qeight, orten!ion $rod#ced " m#!cle action on the joint. It i! the !ame t$e of force.In mo!t of the!e joint!, the e!ta"li!hment of an intermittent &ac##m$romote! a !ilent Qater circ#lation into the joint,onl to "e !(#eeed o#t " the $re!!#re "orne a! a re!#lt of jointacti&it. 2o $re&ent "acY $ain, one need! to drinY!#\cient Qater and do a !erie! of !$ecial e%erci!e! to create anintermittent &ac##m to draQ Qater into the di!ce!$acio.2he!e e%erci!e! Qill al!o red#ce the !$a!m in the "acY m#!cle!

that in a &a!t majorit of $eo$leZ :>$ercent of all "acY $ain!Zi! the main ca#!e of loQer "acY $ain.1ne al!oneed! to ado$t correct $o!t#re!. la!#"ject of "acY $ain and it! relation!hi$ to Qater i! !o im$ortant to#nder!tand that I ha&e dealt Qith it in a !$ecial"ooY, HoQ to Deal Sith BacY /ain and Rhe#matoid Joint /ain, and acom$lementar &ideo, HoQ 2o Deal SithBacY /ain.

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If o# get "acY $ain and, in $artic#lar, !ciatic $ain, o# Qill "enet "reading the "ooY andor !eeing the &ideo. en

majorit of ca!e!, !ciatic $ain can "e totall relie&ed Qithin half an ho#r,Qhen the !$ecial mo&ement! that $rod#cean intermittent &ac##m in the di!c !$ace!Z!hoQn in the "ooY and the&ideoZare $erformed.Bad $o!t#reZYee$ing the head "ent for long $eriod! of time QhenQriting, QorYing at a loQ "ench, 7freee $o!ition7QorYing at the com$#ter for man ho#r!, "ad $illoQ, or too man $illoQ!Zcan "e contri"#tor factor! in the$rod#ction of necY $ain or e&en the di!$lacement of the inter&erte"raldi!c! in the necY. NecY mo&ement i!e!!ential for the e!ta"li!hment of ade(#ate #id circ#lation Qithin the

di!c !$ace! in the necY. 2he Qeight of thehead force! Qater o#t of the di!c! o&er a $eriod of time. 2o "ring "acYthe !ame Qater, the force of &ac##m ha! to"e created Qithin the !ame di!c !$ace. 2hi! can onl "e done if the headand necY are mo&ed ade(#atelhacia atr)!.A !im$le $roce!! in le!! !e&ere ca!e! of necY $ain from di!cdi!$lacement Qo#ld "e !loQl and re$eatedl "endingthe head and necY "acYQard, a! m#ch a! the Qill "end.Kee$ing thenecY e%tended for 8> !econd! at a time. e!te$rolonged e%ten!ion Qill enhance the force of &ac##m and "ring Qater

into the di!c !$ace!. Al mi!mo tiem$o,"eca#!e of their front attachment to the !$inal ligament, all of the di!c!Qill "e retracted "acY into their normal!$ace! "etQeen the &erte"rae and aQa from the ner&e root! in thenecYAnother !im$le $roced#re to correct thi! $ro"lem i! ling on oneT! "acYon the &er edge of the "ed Qith the headhanging "acY and doQn. 2hi! $o!t#re $ermit! the Qeight of the head to!tretch the non*Qeight*"earing necY and"end it "acYQard. A feQ moment! in thi! $o!ition "eing totall rela%edQill ea!e the ten!ion in the necY 2hi! i! a

good $o!t#re to generate a t$e of &ac##m in the di!c !$ace! in thenecY After gentl "ending the head "acYQard!o that o# can !ee the oor, rai!e the head #ntil o# !ee the Qallnearer o#r feet. 2hi! $roced#re ma "e e[ecti&ein creating an intermittent &ac##m in the &erte"ral !$ace! "etQeen antQo &erte"rae. 2he &ac##m draQ! Qater intothe di!c !$ace! and !$read! it to all $art! in the necY joint! andl#"ricate! their mo&ement!. 2hi! Qater i! needed to

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"e a"!or"ed " the di!c core #ntil it re*e%$and! to it! nat#ral !ie, jacYing #$ and !e$arating

one &erte"ra from the other. Oo# co#ld noQ "end the head from one !ideto the other. 2r to looY at the Qall andoor of the room, r!t one !ide and then the other !ide. /eo$le Qho"egin to !#[er from necY 7arthriti!,7 or di!cdi!$lacement in the necY, ma Qi!h to te!t thi! !im$le $roced#re toim$ro&e the mo"ilit of their necY joint!.ANINAL /AINFor more information read the !ection on chole!terol. In "rief and toaddre!! the dehdration*$rod#ced $ain! of the"od together, anginal $ain mean! Qater !hortage in the "od4 2hecommon factor to all of the &ario#! condition!

la"eled a! di[erent di!ea!e! of the heart and the l#ng! i! an e!ta"li!heddehdration. 2aYe a looY at Mr. 0amLig#oriT! and Loretta John!onT! letter!, $#"li!hed " their Yind $ermi!!ionamong the te!timonial! in the !ection onchole!terol, $age! ?;*?8G.Mr. Lig#oriT! anginal $ain di!a$$eared Qhen he!tarted to increa!e hi! Qater intaYe. 'lal!o ha! !#[ered from hiat#! hernia.2hat too ha! !tarted to clear#$.i&en time, it Qill clear #$ com$letel. tam"i'ntaYe a looY at Loretta John!onT! letter. Oo# Qill !ee that e&en at theo#ng*at*heart age of ?>, her anginal $ain can"e treated Qith Qater to the e%tent that !he doe! not need an

medication for her heart $ain!.D1L1RE0 DE CABE`AIn m $er!onal e%$erience, migraine headache! !eem to "e "ro#ghta"o#t " dehdration e%ce!! "ed co&er! thatQill not $ermit the "od to reg#late it! tem$erat#re d#ring !lee$alcoholic "e&erage! hango&erG initiating a $roce!!of cell#lar dehdration, $artic#larl in the "raindietar or allergictrigger! for hi!tamine relea!e e%ce!oen&ironmental heat Qitho#t Qater intaYe. Ba!icall, migraine !eem! to"e an indicator of critical "od tem$erat#rereg#lation at time! of 7heat !tre!!.7 Dehdration $la! a major role in

the $reci$itation of migraine headache!. 2he mo!t $r#dent Qa of dealing Qith migraine i! it! $re&ention " thereg#lar intaYe of Qater. 1nce migraine"reaY! the $ain "arrier!, a ca!cade of chemical reaction! Qill !to$ the"od from f#rther acti&it. At thi! time, onema "e forced to taYe $ain*relie&ing medication! Qith co$io#! Qater.0#\cient cold or iced Qater ma " it!elf "e

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a"le to cool the "od al!o the "rainG from in!ide and $romote clo!ing of the &a!c#lar !!tem e&erQhere. e%ce!o

dilation of the $eri$heral &e!!el! might Qell "e the "a!ic ca#!e of migraine headache.Mr!. Ma&i! B#tler, a to#ring A#!tralian Ad&enti!t mi!!ionar in 0ilang inthe /hili$$ine!, ha! an intere!ting hi!tor.0he ha! for ear! !#[ered from migraine headache!. 0he Qo#ld at time!"e !o inca$acitated a! to "ecome "ed*ridden. 0he came acro!! thi! "ooY Qhen !he Qa! in 0ilang and !tarted toincrea!e her Qater intaYe. 0he Qrote tome that !he ha! !o im$ro&ed that !he noQ Qant! to !ho#t it from theho#!e to$!. Read her letter. Her! i! another oftho!e h#man !torie! that maYe one Qonder HoQ i! it $o!!i"le that Qe

Qere !o ignorant of the im$ortance of Qater tohealth that $eo$le co#ld !#[er from it! lacY in the "od, to the $oint of Qi!hing to die/.1.Bo% 5@5?, Inni!fail =:@> North P#een!land, A#!tralia Jan#ar ;8,5??9Dear Dr. Batmanghelidj4For man ear! I !#[ered Qith headache!. I con!#lted doctor!,ne#rologi!t!, chiro$ractor! and !$ent h#ndred! ofdollar! for head*!can! and *ra!, all to no a&ail. At time! onl m faithin od Ye$t me from Qanting to die, a! I lie$rone on m "ed for da! on end in $ain.

No medication Qo#ld e&er !to$ the $ain, it Qo#ld j#!t !eem to r#n it!co#r!e and then !to$. I co#ld ne&er maYe anconnection "etQeen m diet and the headache!, and the onl $atternthe !eemed to folloQ Qa! to alQa! !tart aco#$le of ho#r! after a meal. 2hen one da a friend told me that he tho#ght m headache! Qereca#!ed "eca#!e I ne&er dranY eno#gh Qater.Shile I YneQ I didnTt act#all drinY m#ch Qater, I tho#ght m her"al teaQith fr#it j#ice! together Qith lot! of fr#it!am$l !#$$lied m li(#id re(#irement!. J#!t three QeeY! later I Qa!leang thro#gh a health magaine Qhen an

ad&erti!ement for o#r "ooY, 7Oo#r BodT! Man Crie! for Sater,7 j#!t!eemed to lea$ o#t at m ee!. I "o#ght themagaine and !ent for the "ooY.Shen it came, I eagerl read and re*read it to learn thi! neQ conce$ta"o#t Qater, and a! I !aQ the error! in mdrinYing ha"it! I (#icYl !et a"o#t to righting them. Can anone, Qitho#te%$eriencing it for them!el&e!, reall

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#nder!tand Qhat it i! liYe to ha&e #!#all $ain*lled da! changed toQonderf#l $ainle!! da! Qhen o# can do the

thing! o# Qant to do, in!tead of "eing 7doQn Qith a headache 7 1h,!#ch a "le!!ing for Qhich I thanY odcontin#all.It ha! taYen month! to $ro$erl hdrate m "od, "#t noQ a headache i!a noQ*and*again e&ent in!tead of thenorm. I thanY a lo&ing and caring od for leading me !te$ " !te$ to thi!Qonderf#l tr#th. He no do#"t tried to leadme a lot earlier, "#t I Qa! too "lind to !ee. I thanY o# doctor for o#rgreat QorY and $er!e&erance in "ringing thi!tr#th to the $eo$le.I lect#re to ad#lt! at night cla!!e! on 7"etter Food and Eating Ha"it!7

and I (#icYl ga&e one of m !e!!ion! entirelto the "odT! need for Qater. I ha&e "een a"le to hel$ man $eo$le to"etter health and m#ch le!! $ain in their li&e!,Qith thi! YnoQledge. A friend told me he Qa! going into ho!$ital, in a feQda! time for !tomach and #lcer treatment.I "egged him to cancel thi! and tr the Qater treatment o#&erecommended.He !omeQhat rel#ctantl did and Qa! amaed and thanYf#l to nd hi!$ain! !to$ and in time, to YnoQ that the #lcerhad healed, all Qitho#t medication./lea!e let me o[er m gratef#l thanY! again and $ra that the Lord Qill

"le!! and g#ide o# and o#r !ta[ a! o#QorY for the "etter health of h#manit.Atentamente,Mr!.G Ma&i! B#tler02RE00 AND DE/RE00I1N72he rea!ona"le man ada$t! him!elf to the Qorld4 the #nrea!ona"le one$er!i!t! in tring to ada$t the Qorld to!+ mi!mo.2herefore all $rogre!! de$end! on the #nrea!ona"le man.7eorge Bernard 0haQA !tate of de$re!!ion i! !aid to e%i!t Qhen the "rain, in confronting a!tre!!f#l emotional $ro"lem, nd! it di\c#lt to

co$e Qith other attention*demanding action! at the !ame time. 2hi!$henomenon can "ecome !o all*a"!or"ing a!to inca$acitate the $er!on. In the long r#n, !#ch a !tre!!f#l drain on"rain acti&it can $rod#ce di[erentmanife!tation! that are la"eled according to the $er!onT! o#tQard"eha&ior $attern. 2en million American! are !aid to "e !#[ering from one form or anotherof !#ch condition!. Innitel greater

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n#m"er! are e%$eriencing, or Qill at one time or another e%$erience, themilder form! of de$re!!ion. Alg#na forma de

de$re!!ion i! a nat#ral $henomenon in the $roce!! of de&elo$ment and$rogre!! of an indi&id#al. It i! in the!e!tate! of con!#ming mental acti&it that character! are de&elo$ed andthe inner mettle of the indi&id#al i! forged.Nat#rall, co$ing Qith di[erent a!$ect! of oneT! negati&e feeling! i! $artand $arcel of the $roce!!. Almo!t alQa!,the !tate of de$re!!ion i! a $a!!ing $henomenon if lo&e, care, andem$ath are a&aila"le to n#dge the indi&id#al inthe direction of a re!ol#tion of negati&e inner tho#ght!.Unfort#natel, !ome $eo$le Qill not "e a"le to co$e Qith the fear,an%ietie!, and anger! a!!ociated Qith de$re!!ion.

In !eeYing $rofe!!ional hel$, the are gi&en !ome form of medication. Atthe on!et of chemical treatment ofde$re!!ion, the medication! Qere le!! harmf#l.2oda, the are &er$oQerf#l and !ometime! dangero#!. alg#no!form of them Qill !tri$ from tho!e treated the a"ilit to emotionall feelfor them!el&e!, a! Qell a! for other!. Alg#no! dethe!e medication! can de!tro em$ath and % a negati&e idea in$artic#larl &#lnera"le $er!on!. 2he ma moreea!il "ecome !#icidal, a! Qell a! anti!ocial and homicidal.Shat I am e%$laining in thi! cha$ter i! the rea!on for the ine\cienc of the $h!iolog a!!ociated Qith !tre!! and

la de$re!ión.Shat I $ro$o!e i! the Qa to increa!e the e\cienc of "rain$oQer to co$e Qith e%tremel !e&ereemotional !tre!! and it! o#tQard manife!tation! of de$re!!ion. I, m!elf,ha&e e%$erienced, and ha&e o"!er&ed inman other!, all of the $o!iti&e a!$ect! to Qhat I am $ro$o!ing to o#reader!./atholog that i! !een to "e a!!ociated Qith 7!ocial !tre!!e!7Zfear,an%iet, in!ec#rit, $er!i!tent emotional andmatrimonial $ro"lem!Zand the e!ta"li!hment of de$re!!ion are there!#lt! of Qater decienc to the $oint that theQater re(#irement of "rain ti!!#e i! a[ected. 2he "rain #!e! electrical

energ that i! generated " the Qater dri&e ofthe energ*generating $#m$!.Sith dehdration, the le&el of energgeneration in the "rain i! decrea!ed. m#cho!f#nction! of the "rain that de$end on thi! t$e of energ "ecomeine\cient. Se recognie thi! inade(#ac off#nction and call it de$re!!ion. 2hi! 7de$re!!i&e !tate7 ca#!ed "dehdration can lead to chronic fatig#e !ndrome.

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 2hi! condition i! a la"el $#t on a !erie! of ad&anced $h!iological$ro"lem! that are !een to "e a!!ociated Qith

e!tr'!.If Qe #nder!tand the e&ent! that taYe $lace in !tre!!, Qe Qill al!o#nder!tand chronic fatig#e !ndrome. En todo ca!o,after a $eriod of time of correcting for dehdration and it! meta"oliccom$lication!, chronic fatig#e !ndrome Qillim$ro&e "eond recognition. 2he folloQing $age! dene the$h!iological e&ent! and the $o!!i"le meta"olico&erride! that can lead to de$letion of certain "od re!er&e! that ma "ethe "a!ic $ro"lem in chronic fatig#e!+ndrome. 2HE INI2IALLO 0ILEN2 C1M/EN0A2I1N MECHANI0M0 A001CIA2ED SI2H

DEHODRA2I1NShen the "od "ecome! dehdrated, the $h!iological $roce!!e! thatQill e!ta"li!h are the !ame one! that occ#rQhen co$ing Qith !tre!!. Dehdration e(#al! !tre!!, and once !tre!!e!ta"li!he!, there i! an a!!ociatedmo"iliation of $rimar material! from "od !tore!. 2hi! $roce!! Qill7mo$ #$7 !ome of the Qater re!er&e! of thec#er$o.Con!e(#entl, dehdration ca#!e! !tre!!, and !tre!! Qill ca#!ef#rther dehdration.In !tre!!, !e&eral hormonal o&erride! "ecome o$erati&e. 2he "oda!!#me! a cri!i! !it#ation and Qill "egin to

mo"ilie for a 7ght or ight7 re!$on!e.2he "od doe! not !eem torecognie the !ocial tran!formation of h#man!. loa!!e!!e! all !it#ation! of 0tre!! a! tho#gh a 7ght or ight7 !tance ha!to "e maintained, e&en Qith !tre!!e!a!!ociated Qith QorY in an o\ce. 0e&eral !trong hormone! "ecome!ecreted and Qill remain 7triggered7 #ntil the"od get! o#t of it! !tre!!f#l circ#m!tance!. 2he!e hormone! are mainlendor$hin!, corti!one relea!e factor,$rolactin, &a!o$re!!in, and renin*angioten!in.END1R/HIN0, C1R2I01NE, /R1LAC2IN, AND A01/RE00INEndor$hin! $re$are the "od to end#re hard!hi$ and inj#r #ntil it get!

o#t of danger. 2he al!o rai!e the $ain#m"ral.Sith an inj#r that Qo#ld ha&e ca#!ed $ain at a loQer le&el, Qiththe 7#m"rella7 of endor$hin!, the "odQill "e a"le to contin#e Qith it! ta!Y. Beca#!e of child"irth and monthlmen!tr#ation, Qomen !eem to acce!! thi!hormone m#ch more readil. 2he generall ha&e a greater a"ilit toQith!tand $ain and !tre!!.

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Corti!one Qill initiate the remo"iliation of !tored energie! and raQmaterial!. Fat i! "roYen doQn into fatt acid! to

"e con&erted into energ. 0ome $rotein! are once again "roYen doQninto the "a!ic amino acid! for the formationof e%tra ne#rotran!mitter!, neQ $rotein!, and !ome !$ecial amino acid!to "e "#rned " the m#!cle!. d#rante$regnanc and at the time of feeding milY to the child, thi! hormone andit! 7a!!ociate!7 Qill mo"ilie a #niform oQof $rimar material! for the $#r$o!e of o[!$ring de&elo$ment. If theaction of corti!one contin#e! for long, !oonthere Qill "e !ome !electi&e de$letion from the amino acid re!er&e! of the "od.Under the in#ence of corti!one, the "od contin#e! to 7feed o[ it!elf.7

 2he e[ect of corti!one i! de!igned to $ro&ideemergenc raQ material! for the $rod#ction of mo!t e!!ential $rimar$rotein! and ne#rotran!mitter!Zto get the"od ro&er the h#m$.7 It i! not de!igned for the contin#ed "reaYdoQn of material! em$loed in the maintenance ofthe !tr#ct#ralintegrit of the "od. It i! thi! $henomenon that $rod#ce!the damage a!!ociated Qith !tre!!, if the7!tre!!or7 maintain! it! #na"ated in#ence./rolactin Qill maYe !#re that the lactating mother Qill contin#e to$rod#ce milY. All !$ecie! ha&e it. /rolactin Qill$rime the gland cell! in the "rea!t to contin#e milY $rod#ction e&en if 

there i! dehdration or !tre!! that Qill ca#!ela de!hidratación.It Qill $rime the gland cell! to regenerate and increa!ein (#antit.Se !ho#ld remem"er that altho#gh Qe concentrate on the !olidcom$o!ition of the milY, it i! it! Qater content that i!of $rimar im$ortance to the groQing fet#!. E&er time a cell gi&e! ri!eto a da#ghter cell, <9 $ercent or more of it!&ol#me ha! to "e lled Qith Qater. In !hort, groQth de$end! on thea&aila"ilit of Qater. Shen 7Qater7 i! "ro#ght tothe area, the cell! Qill "e a"le to acce!! it! other di!!ol&ed content!. 2hi! hormone i! al!o made in the $lacenta and

!tored in the amniotic #id !#rro#nding the fet#!.In !hort, thi! hormoneha! a 7mamotro$hic7 action. E!to hace (#e el"rea!t gland! and their d#ct! groQ. roQth hormone ha! m#ch !imilaritto $rolactin. 2he ha&e !imilar action!,e%ce$t that $rolactin mainl target! the organ! of re$rod#ction.It ha! "een !hoQn in mice that increa!ed $rolactin $rod#ction Qill ca#!emammar t#mor!. In 5?:<,5 $ro$o!ed in

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m g#e!t lect#re addre!! of an internationall gathered !elect gro#$ of cancer re!earcher! that chronic dehdration

in the h#man "od i! a $rimar ca#!ati&e factor for t#mor $rod#ction. 2he relation!hi$ "etQeen !tre!!, age*de$endent chronic dehdration, $er!i!tent $rolactin !ecretion, andcancer tran!formation of the gland#lar ti!!#e inthe "rea!t !ho#ld not "e o&erlooYed. A reg#lar adj#!tment to the dailQater intaYe in QomenZ$artic#larl Qhenconfronting !tre!!e! of e&erda lifeZQill at lea!t !er&e a! a $re&enti&emea!#re again!t $o!!i"le de&elo$ment of!tre!!*ind#ced "rea!t cancer in the age gro#$ of Qomen $redi!$o!ed tothi! $ro"lem and $ro!tate cancer in men.a!o$re!!in reg#late! the !electi&e oQ of Qater into !ome cell! of the

"od. It al!o ca#!e! a con!triction of theca$illarie! it acti&ate!. A! it! name im$lie!, it ca#!e! &a!o*con!triction. Iti! $rod#ced in the $it#itar gland and!ecreted into the circ#lation. Shile it ma con!trict "lood &e!!el!, !ome&ital cell! $o!!e!! recei&ing $oint!rece$tor!G for thi! hormone. De$ending on the hierarch of theirim$ortance, !ome cell! !eem to $o!!e!! more&a!o$re!!in rece$tor! than other!. 2he cell mem"raneZthe $rotecti&e co&ering of cell architect#reZ i!nat#rall de!igned in tQo laer!. 2#ning*forY*liYe !olid hdrocar"on 7"ricY!7 are held together " the adhe!i&e

$ro$ert of Qater !ee Fig#re 5=, $age :9G. en"etQeen the tQo laer! there i! a connecting $a!!ageQa Qhereenme! tra&el, !electi&el react together, andca#!e a de!ired action Qithin the cell. 2hi! QaterQa QorY! &er m#chliYe a moat or 7"eltQa,7 e%ce$t that it i! aQater*lled 7"eltQa7 and e&erthing ha! to oat in it.Shen there i! !#\cient Qater to ll all the !$ace!, the moat get! lledand Qater Qill al!o get into the cell. hama come a time Qhen the rate of Qater oQ into the cell ma not "e!#\cient, and !ome of the cell f#nction! ma"ecome a[ected. 2o !afeg#ard again!t !#ch a $o!!i"le cata!tro$hic

!it#ation, nat#re ha! de!igned a magnicentmechani!m for the creation of Qater lter! thro#gh the mem"rane.Shen &a!o$re!!in hormone reache! the cellmem"rane and f#!e! Qith it! !$eciall de!igned rece$tor, the rece$torcon&ert! to a 7!hoQer head7 !tr#ct#re andmaYe! $o!!i"le ltration of onl Qater thro#gh it! hole!. 2he im$ortant cell! man#fact#re the &a!o$re!!in rece$tor in greater(#antit. a!o$re!!in i! one of the hormone!

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in&ol&ed in the rationing and di!tri"#tion of Qater according to a $riorit$lan Qhen there i! dehdration. La! c'l#la! ner&io!a!

!eem to e%erci!e their $riorit " man#fact#ring more &a!o$re!!inrece$tor! than other ti!!#e cell!. Nece!itanYee$ the QaterQa! in their ner&e! f#ll f#nctional 2o maYe !#re theQater can $a!! thro#gh the!e tin hole! Qhichonl alloQ the $a!!age of one Qater molec#le at a timeG, &a!o$re!!inal!o ha! the $ro$ert of ca#!ing&a!ocon!triction and $#tting a !(#eee on the #id &ol#me in the region. 2h#!, the h$erten!i&e $ro$ert of the ne#rotran!mitter &a!o$re!!inZ"etter YnoQn a! a hormoneZi! needed to"ring a"o#t a !tead ltration of Qater into the cell!, onl Qhen the freeoQ and direct di[#!ion of Qater thro#gh the

cell mem"rane i! in!#\cient Fig#re 5> i! de!igned to e%$lain thi!mechani!m. For more information on the cellmem"rane, read the !ection on chole!terol.ALC1H1LAlcohol Qill !#$$re!! the !ecretion of &a!o$re!!in from the $it#itargland. LacY of &a!o$re!!in in circ#lation Qilltran!late to general dehdration of the "odZe&en in the "rain cell!.NoQ, a $re&io#!l !light and ea!ier*to*adj#!t*todehdration Qill tran!late to a &er !e&ere dro#ght in the 7!en!iti&ecell!7 of the "rain. 2o co$e Qith thi! 7!tre!!,7more of the &ario#! hormone! are !ecreted, incl#ding the "odT! oQn

addicti&e endor$hin!. 2h#!, $rolonged #!e of alcohol ma "e in!tr#mental in $romotingaddicti&e tendencie! to endor$hin !ecretion in the"odZ triggering the !ecretion of e%ce!! endor$hin!. Somen, "eca#!eof their nat#ral tendenc to increa!edendor$hin $rod#ction to co$e Qith child"irth and their monthlmen!tr#ation, !eem to "ecome addicted to alcoholmore readil than men. It !eem! that Qomen "ecome addicted toalcohol in a"o#t three ear! com$ared to men,Qho ma "ecome com$#l!i&e drinYer! in a"o#t !e&en ear!.Fig#re! 5> and 55 Qill e%$lain !ome of the $o!!i"le contri"#tor factor!

to the de&elo$ment of chronic fatig#e!ndrome d#ring an e%$anding chronic dehdration. It can occ#r fromthe reg#lar intaYe of ca[eine*containing andalcoholic "e&erage! in $lace of Qater. a!o$re!!in rece$tor i! nat#rallde!igned to Yee$ the QaterQa! in thener&e !!tem! f#ll to$$ed #$. Nat#rall, in dehdration of the ner&e!!tem, the energ and &olition to do neQ QorYi! dra!ticall red#ced.

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 2he Yidne! are re!$on!i"le for #rine $rod#ction and the e%cretion of e%ce!! hdrogen, $ota!!i#m, !odi#m, and

materiale! de de!echo.All of the!e f#nction! ha&e to "e maintained$ro$ortionate to the !#\cient a&aila"ilit of Qater to "e#!ed to maYe #rine. It i! tr#e the Yidne! ha&e the a"ilit to concentratethe #rine. HoQe&er, thi! a"ilit i! not to "e#!ed to it! e%treme at all time!, or it Qill e&ent#all $rod#ce Yidnedamage. 2he RA !!tem i! the $i&otal mechani!m for the re!toration of #id&ol#me in the "od. It i! one of the !#"ordinatemechani!m! to hi!tamine acti&it for Qater intaYe. It reg#late! the&a!c#lar "ed to adj#!t for the #id content of thecirc#lation !!tem. It! acti&it i! decrea!ed " the $re!ence of more !alt

and Qater to ll the #id ca$acit of the&a!c#lar "ed.In the Yidne!, it !en!e! the #id oQ and the ltration$re!!#re for it! #rine*maYing !!tem. 0i elltration $re!!#re i! not ade(#ate for #rine ltration and !ecretion, theRA !!tem Qill tighten the "lood &e!!el! inthi! organ.Shen the Yidne! are damaged and #rine $rod#ction i! in!#\cient, theRA !!tem i! more acti&e. It $romote! more!alt intaYe and ind#ce! more thir!t. Kidne damage ma "e thecon!e(#ence of long*term dehdration and !altde$letion that had triggered the RA !!tem acti&it in the r!t $lace. B#t

Qe ha&e not in the $a!t recognied the!ignicance of the &a!c#lar tightening e!!ential h$erten!ionG a! anindicator of "odT! #id lo!!. NoQ, in!#\cient#id "alance in the "od ma ha&e to "e con!idered a! the $rimarfactor in !ome ca!e! of renal damageZto the$oint of needing Yidne re$lacement. 1nce the RA !!tem i! t#rned f#ll1N, it contin#e! it! e%$anding $ace #ntil anat#ral !Qitching !!tem co#ld t#rn it o[. 2he com$onent! of the nat#ral1FF !Qitch are SA2ER and !ome 0AL2Zin that orderZ#ntil the mea!#ra"le &a!c#lar tightening indicate! anormal range.

 2he !ali&ar gland! !eem to ha&e the a"ilit to !en!e !alt !hortage in the"od. Shen there i! !odi#m !hortage,the !eem to $rod#ce !#"!tance! called Yinin!. Kinin! $romote added"lood circ#lation and increa!ed !ali&aformation in the !ali&ar gland!. 2hi! increa!ed !ali&a formation$o!!i"l to the e%tent that it Qo#ld oQ o#t of themo#thG !er&e! tQo $#r$o!e!4 1ne, it l#"ricate! the mo#th d#ring foodintaYe in a dehdrated !tate of the "od tQo,

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it! alYaline con!i!tenc and co$io#! oQ Qill a!!i!t in food "reaYdoQnand it! e&ent#al e&ac#ation from the

e!tómago.Sithin the integrated !!tem! of the h#man "od, the Yinin!of the !ali&ar gland !eem to al!o triggeracti&ation of the RA !!tem that Qill "egin to in#ence all $art! of the"od. 2h#!, !odi#m !altG !hortage in the "od Qhich Qo#ld al!o contri"#te tode&a!tating Qater !hortage o#t!ide of cell!Gco#ld initiate a !erie! of e&ent! that Qo#ld #ltimatel $rod#ce e!!entialh$erten!ion and chronic $ain! in h#man!. 2he relation!hi$ of the !ali&ar Yinin! to !odi#m de$letion !alt de$letionca#!e! "od Qater content lo!!G and am$le!ali&a $rod#ction, e&en if the "od i! fairl dehdrated, i! the $arado% in

the nat#ral de!ign of the h#man "od. loe%$o!e! the gro!!e!t error in con!idering the 7dr mo#th7 a! the !oleindicator of Qater !hortage in h#man!Beca#!e of thi! &er !im$le error, the $ractice of medicine and !cienticre!earch are light ear! o[ co#r!e. m#cho"acYtracYing and re&i!ion to the alread ado$ted &ieQ! Qill "e#na&oida"le. Let #! ho$e 7!elf $rotection7 Qill not "ean o"!tacle in the QaShat ha$$en! if Qe drinY tea, co[ee, or cola! in $lace of Qater Nat#ral!tim#lant! in co[ee and tea are larger(#antitie! of ca[eine and le!!er amo#nt! of theo$hlline theafelinG.

 2he!e are central ner&o#! !!tem !tim#lant!at the !ame time, the are dehdrating agent! "eca#!e of their !trongdi#retic action on the Yidne!. 1ne c#$ ofco[ee contain! a"o#t :9 milligram! of ca[eine, and one c#$ of teacontain! a"o#t 9> milligram! of ca[eine. ColadrinY! contain a"o#t 9> milligram! of ca[eine, $art of Qhich i! added to!tandardie the reci$e Qhen e%tracting theacti&e !#"!tance! from the n#t! of CoY acc#minata. 2he!e central ner&o#! !!tem !tim#lant! li"erate energ from the A2/!torage $ool and con&ert A2/ to it! "#rnt!tage of cclic AM/ in the cell!Zat certain le&el! a !trong inhi"itor

agent. 2he al!o relea!e energ from li"erationof calci#m from it! !tored form in the cell!. 2h#!, ca[eine !eem! to actin an energ relea!ing ca$acit in the "od.Se all YnoQ a"o#t thi! nal e[ect of ca[eine Qhat Qe !ho#ld al!o YnoQi! it! o&erride e[ect Qhen the "od doe!not Qi!h to relea!e energ for a certain action. In thi! Qa, the action of !ome hormone! and tran!mitter! Qill not "e

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limited at a later time "eca#!e of a $o!!i"le loQer le&el of !tored energ.Ca[eine Qill ca#!e an o&erride e[ect #ntil

a loQer le&el of energ !torage i! reached. Cola drinY! ha&e e%actl the!ame e[ect. 2he e[ect of ca[eine ma at time! "e con!idered de!ira"le, "#t con!tant!#"!tit#ting of ca[eine*containing drinY!for Qater Qill de$ri&e the "od of it! f#ll ca$acit for the formation of hdroelectric energ. E%ce!! ca[eine Qill al!ode$lete the A2/*!tored energ in the "rain and the "odZa $o!!i"lecontri"#ting factor for !horter attention !$an inthe o#nger, cola*con!#ming generation, or chronic fatig#e !ndrome a!a re!#lt of e%ce!! co[ee con!#m$tion Inla &ida $o!terior.E%ce!! ca[eine intaYe Qill e&ent#all e%ha#!t the heart

m#!cle "eca#!e of it! o&er*!tim#lation.Recentl, in !ome e%$erimental model!, it ha! "een !hoQn that ca[eineinhi"it! a mo!t im$ortant enme !!temZ/DE $ho!*$ho*di*e!tera!eGZthat i! in&ol&ed in the $roce!! of learningand memor de&elo$ment. In re$ortede%$eriment!, ca[eine im$aired &i!ion and memor com$onent! of thelearning a"ilit in the !$ecie! in&ol&ed in thee%$erimento. Oo# m#!t noQ realie Qh $eo$le Qith AlheimerT! di!$a!e and childrenQith learning di!a"ilit !ho#ld not drinYanthing other than Qater. Denitel no ca[eine*containing "e&erage!

!ho#ld "e con!#med.Let #! noQ connect all the information in thi! cha$ter Qith tQo di[erent"#t related $ro"lem!4 h$erten!ion andchole!terol formationZ"oth leading to heart $ro"lem!. 2he o$erating mechani!m for ada$tation to dehdration, Qhich Qillclima% into &a!ocon!triction, are the !ame a!mentioned for !tre!!. Namel, the contin#ed action! of &a!o$re!!in andthe RA !!tem are re!$on!i"le fore!ta"li!hing the nece!!ar ada$tation to dro#ght. 2he clo!e a n#m"erof o$en ca$illarie! in the &a!c#lar "ed andincrea!e the $re!!#rein the re!t to !(#eee Qater thro#gh the

mem"rane! into the cell! in 7$riorit organ!.7 noforget4 Dehdration i! the n#m"er one !tre!!or of the h#man "odZoran li&ing matter./RE0IN AR2ERIAL AL2A7/h!ician! thinY the are doing !omething for o# " la"eling *Qhat o#ha&e a! a di!ea!e.7 Imman#el KantHigh "lood $re!!#re e!!ential h$erten!ionG i! the re!#lt of an ada$ti&e$roce!! to a gro!! "od Qater decienc.

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 2he &e!!el! of the "od ha&e "een de!igned to co$e Qith the #ct#ationof their "lood &ol#me and ti!!#e

re(#irement! " o$ening and clo!ing di[erent &e!!el!. Shen the total#id &ol#me in the "od i! decrea!ed, themain &e!!el! al!o ha&e to decrea!e their a$ert#re clo!e their l#menGotherQi!e there Qo#ld not "e eno#gh #id toll all the !$ace allocated to "lood &ol#me in the de!ign of that $artic#lar"od. Failing a ca$acit adj#!tment to the7Qater &ol#me7 " the "lood &e!!el!, ga!e! Qo#ld !e$arate from the"lood and ll the !$aceca#!ing 7ga! locY!.7 2hi! $ro$ert of l#men reg#lation for #id circ#lation i! a mo!t ad&ancedde!ign Qithin the $rinci$le of hdra#lic!and after Qhich the "lood circ#lation of the "od i! modeled.

0h#nting of "lood circ#lation! a normal ro#tine. Shen Qe eat, mo!t of the circ#lation i! directed into the inte!tinaltract " clo!ing !ome ca$illar circ#lation el!eQhere. Shen Qe eat, moreca$illarie! are o$ened in thega!trointe!tinal tract and feQer are o$en in the major m#!cle !!tem!.1nl area! Qhere acti&it $lace! a more#rgent demand on the circ#lator !!tem! Qill "e Ye$t f#ll o$en for the$a!!age of "lood. En otra! $ala"ra!, e! la"lood*holding ca$acit of the ca$illar "ed that determine! the directionand rate of oQ to an !ite at a gi&en time. 2hi! $roce!! i! nat#rall de!igned to co$e Qith an $riorit QorY Qitho#t

the "#rden of maintaining an e%ce!! #id&ol#me in the "od. Shen the act of dige!tion ha! taYen $lace and le!!"lood i! needed in the ga!trointe!tinalregion, circ#lation to other area! Qill o$en more ea!il. In a mo!t indirectQa, thi! i! Qh Qe feel le!! acti&eimmediatel after a meal and read for action after !ome time ha!$a!!ed. In !hort, there i! a mechani!m fore!ta"li!hment of $riorit for circ#lating "lood to an gi&en areaZ!omeca$illarie! o$en and !ome other! clo!e. laorder i! $redetermined according to a !cale of im$ortance of f#nction. 2he "rain, l#ng!, li&er, Yidne!, and gland!

taYe $riorit o&er m#!cle!, "one!, and !Yin in "lood di!tri"#tionZ#nle!!a di[erent $riorit i! $rogrammed into the!i!tema.2hi! Qill ha$$en if a contin#ed demand on an $art of the "odQill in#ence the e%tent of "lood circ#lationto the area, !#ch a! m#!cle de&elo$ment thro#gh reg#lar e%erci!e.SA2ER 0H1R2AE4 /12EN2IAL0 F1R HO/ER2EN0I1NShen Qe do not drinY eno#gh Qater to !er&e all the need! of the "od,!ome cell! "ecome dehdrated and lo!e

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!ome of their Qater to the circ#lation. Ca$illar "ed! in !ome area! Qillha&e to clo!e !o that !ome of the !lacY in

ca$acit i! adj#!ted for. In Qater !hortage and "od dro#ght, @@ $ercenti! taYen from the Qater &ol#me normallheld in!ide the cell! ;@ $ercent i! taYen from the &ol#me held o#t!idethe cell! and : $ercent i! taYen from "lood&ol#me !ee Fig#re 58G. 2here i! no alternati&e for the "lood &e!!el!other than clo!ing their l#men to co$e Qith thelo!! in "lood &ol#me. 2he $roce!! "egin! " clo!ing !ome ca$illarie! inle!!*acti&e area!. 1therQi!e, Qhere Qill the"alance come from to Yee$ the!e ca$illarie! o$en 2he decient(#antit m#!t come either from o#t!ide or "etaYen from another $art of the "od

It i! the e%tent of ca$illar "ed acti&it thro#gho#t the "od that Qill#ltimatel determine the &ol#me of circ#lating!angre.2he more the m#!cle! are e%erci!ed, the more their ca$illarie!Qill o$en and hold a greater &ol#me of "loodQithin the circ#lation re!er&e!. 2hi! i! the rea!on Qh e%erci!e i! a mo!tim$ortant com$onent for $h!iologicaladj#!tment! in tho!e !#[ering from h$erten!ion.2hi! i! one a!$ect tothe $h!iolog of h$erten!ion. El ca$ilar"ed m#!t remain o$en and f#ll and o[er no re!i!tance to "loodcirc#lation. Shen the ca$illar "ed i! clo!ed ando[er! re!i!tance, onl an increa!ed force "ehind the circ#lating "lood

Qill en!#re the $a!!age of !ome #id!a tra&'! del !i!tema.Another rea!on Qh the ca$illar "ed ma "ecome !electi&el do!ed i!!hortage of Qater in the "od. B)!icamente,Qater Qe drinY Qill #ltimatel ha&e to get into the cell!ZQater reg#late!the &ol#me of a cell from in!ide. !alreg#late! the amo#nt of Qater that i! held o#t!ide the cell!Zthe oceanaro#nd the cell 2here i! a &er delicate"alancing $roce!! in the de!ign of the "od in the Qa it maintain! it!com$o!ition of "lood at the e%$en!e of#ct#ating the Qater content in !ome cell! of the "od. Shen there i! a

!hortage of Qater, !ome cell! Qill go Qitho#ta $ortion of their normal need! and !ome other! Qill get a$redetermined rationed amo#nt to maintain f#nction a! itQa! e%$lained, the mechani!m in&ol&e! Qater ltration thro#gh the cellmem"raneG. HoQe&er, "lood Qill normallretain the con!i!tenc of it! com$o!ition. It m#!t do !o to Yee$ thenormal com$o!ition of element! reaching the&ital center!.

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 2hi! i! Qhere the 7!ol#te! $aradigm7 i! inade(#ate and goe! Qrong. It"a!e! all a!!e!!ment! and e&al#ation! of

"od f#nction! on the !olid! content of "lood. It doe! not recognie thecom$arati&e dehdration of !ome other $art!del c#er$o.All "lood te!t! can a$$ear normal and et the !mallca$illarie! of the heart and the "rain ma "e clo!edand ca#!e !ome of the cell! of the!e organ! a grad#al damage fromincrea!ing dehdration o&er a long $eriod oftiem$o.Shen o# read the !ection on chole!terol formation, thi!!tatement Qill "ecome more clear.Shen Qe lo!e thir!t !en!ation or do not recognie the other !ignal! of dehdrationG and drinY le!! Qater than thedail re(#irement, the !h#tting doQn of !ome &a!c#lar "ed! i! the onl

nat#ral alternati&e to Yee$ the re!t of the"lood &e!!el! f#ll. 2he (#e!tion i!, hoQ long can Qe go on liYe thi! 2hean!Qer i!, long eno#gh to #ltimatel"ecome &er ill and die. Unle!! Qe get Qi!e to the $aradigm !hift and$rofe!!ionall and generall "egin torecognie the $ro"lem! a!!ociated Qith Qater meta"oli!m di!t#r"ance inthe h#man "od and it! &ariet of thir!t!ignal!, chronic dehdration Qill contin#e to taYe it! toll on "oth o#r"odie! and o#r !ociet.E!!ential h$erten!ion !ho#ld $rimaril "e treated Qith an increa!e indail Qater intaYe. 2he $re!ent Qa of treating

h$erten!ion i! Qrong to the $oint of !cientic a"!#rdit. 2he "od i!tring to retain it! Qater &ol#me, and Qe !a tothe de!ign of nat#re in #!4 7No, o# do not #nder!tandZo# m#!t taYedi#retic! and get rid of Qater7 E! $or loha$$en!, if Qe do not drinY !#\cient Qater, the onl other Qa the "odha! to !ec#re Qater i! thro#gh themechani!m of Yee$ing !odi#m in the "od. 2he RA !!tem i! directlin&ol&ed. 1nl Qhen !odi#m i! retained QillQater remain in the e%tra cell#lar #id com$artment. From thi!com$artment, thro#gh the mechani!m of !hoQer*head $rod#ction, Qater Qill "e forced into !ome of the cell! Qith

7$riorit7 !tat#!. 2h#!, Yee$ing !odi#m in the "odi! a la!t re!ort Qa of retaining !ome Qater for it! 7!hoQer*head7 ltered#!e. 2here i! a !en!iti&it of de!ign attached to !odi#m retention in the "od. 2o a!!#me thi! to "e the ca#!e ofh$erten!ion i! inacc#rate and !tem! from in!#\cient YnoQledge of theQater reg#lator mechani!m! in the h#man

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c#er$o.Shen di#retic! are gi&en to get rid of the !odi#m, the "od"ecome! more dehdrated.2he 7dr mo#th7 le&el

of dehdration i! reached and !ome Qater i! taYen to com$en!ate. 2he#!e of di#retic! maintain the "od at ane%$anding le&el of decit Qater management. 2he do not c#reh$erten!ion the maYe the "od more determinedfor !alt and Qater a"!or$tionZhoQe&er, ne&er eno#gh to correct the$ro"lem. 2hat i! Qh, after a Qhile, di#retic!are not eno#gh and !#$$lemental medication! Qill "e forced on the$atient.Another $ro"lem in a!!e!!ment of h$erten!ion i! it! mean! of mea!#rement. An%iet a!!ociated Qith ha&ingh$erten!ion Qill a#tomaticall a[ect the $er!on at e%amination time.

Reading! of the in!tr#ment! ma not reectthe tr#e, nat#ral, and normal "lood $re!!#re. An ine%$erienced or ha!tmedical $ractitioner, more in fear oflitigation than mindf#l of acc#rac of j#dgment, might a!!#me the$atient to ha&e h$erten!ion, Qherea! the $er!onmight onl ha&e an in!tant of 7clinic an%iet,7 th#! ca#!ing a higherreading of the in!tr#ment. 1ne other &erim$ortant "#t le!!*YnoQn $ro"lem Qith the mechani!m of reading "lood$re!!#re i! the $roce!! of inating the c#[Qell a"o&e the !!tolic reading, and then letting the air o#t #ntil the$#l!e i! heard.

E&er large and $o!!i"l !mallG arter ha! a com$anion ner&e that i!there to monitor the oQ of "lood thro#gh the"#(#e.Sith the lo!! of $re!!#re "eond the c#[ that i! noQ inated to&er high le&el!, the $roce!! of 7$re!!#re7o$ening of the o"!tr#ction in the arterie! Qill "e triggered. B the timethe $re!!#re in the c#[ i! loQered to read the$#l!ation le&el, the recording of an articiall ind#ced higher "lood$re!!#re Qill "ecome #na&oida"le. De!afort#nadamente,the mea!#rement of h$erten!ion i! !o ar"itrar and "a!ed on thedia!tolic le&elG that in thi! litigio#! !ociet aminor error in a!!e!!ment ma la"el a $er!on h$erten!i&e. 2hi! i! Qhen

all the 7f#n and game!7 "eginSater " it!elf i! the "e!t nat#ral di#retic. If the $er!on! Qho ha&eh$erten!ion, and $rod#ce ade(#ate #rine,increa!e their dail Qater intaYe, the Qill not need to taYe an di#retic!.If $rolonged 7h$erten!ion*$rod#cingdehdration7 ha! al!o ca#!ed heart fail#re com$lication!, Qater intaYe!ho#ld "e increa!ed grad#all. In thi! Qa,

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one maYe! !#re that #id collection in the "od i! not e%ce!!i&e and#nmanagea"le.

 2he mechani!m of !odi#m retention in the!e $eo$le i! in an 7o&erdri&e7mode. Shen Qater intaYe i! increa!edgrad#all and more #rine i! "eing $rod#ced, the edema #id 7!Qelling7Gthat i! f#ll of to%ic !#"!tance! Qill "e#!hed o#t, and the heart Qill regain it! !trength. 2he folloQing letter!are $re!ented here Qith the Yind $ermi!!ionof their a#thor!, Qho Qi!hed to !hare their Qelcome e%$erience! Qiththe reader! of thi! "ooY.Dear Dr. Batmanghelidj,No&em"er ;;,5??8I ha&e j#!t ordered another co$ of o#r "ooY on Qater, ha&ing gi&en a

!on m r!t co$. I tell e&er"od a"o#t itand m e%$erience!. /erha$! o# Qo#ld "e intere!ted.M r!t !on Charle!, 9:, Qho li&e! Qith me i! deaf and a#ti!tic. I taYehim 8 or = da! a QeeY to a facilit for thedi!ca$acitado!.2he had "een taYing hi! "lood $re!!#re there andnotied me that the doctor !aid he !ho#ld go onmedication * hi! B/ Qa! 5=>*5@>5>>*5>=.5 had j#!t recei&ed o#r "ooYand a!Yed the M.D. to let me e%$erimentd#rante ; !emana!.Rel#ctantl he agreed, "#t Qarned me it Qa! &erdangero#!.I Ye$t Charle! home and #!ed the Qater ro#tine, al!o adding a little

magne!i#m and $ota!!i#m. 2Qo QeeY! later the n#r!e tooY hi! B/. and it Qa! 5>@:>. 0he !aid*72hedoctor Qill "e in !hortl7* e&identl theM.D. didnTt "elie&e her and he checYed it him!elf and had to admit it Qa!!o. He didnTt a!Y me Qhat I did, !o I didnot tell him a"o#t Qater, "#t if the B/. contin#e! a! it i!, I Qill tell him.I Qent on the Qater ro#tine too Qitho#t an $artic#lar $ro"lem in mind,"#t noticed that in a"o#t 5> da! mtendenc to get di if I mo&ed m head (#icYl had di!a$$eared. I al!ohad "een #na"le to loQer m head to atat night! and had to ha&e !e&eral $illoQ!. NoQ lam m#ch "etter, and

ha&e had onl one !$ell in o&er a month4 I am:; and a 5;. 2hanY o# for the QorY o# are doing * it i! m#ch needed. More $oQer too#. Marjori Ram!a.If o# can nd o#t Qh thi! doctor Qa! not intere!ted in di!co&ering hoQCharle!T! mother "ro#ght hi! "lood$re!!#re "acY to normal, o# Qill then realie Qh Qe ha&e a health carecri!i! on o#r hand!

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Michael /at#ri! i! a felloQ Rotarian. He r!t "ecame aQare of m QorYQhen I Qa! a!Yed to !$eaY "efore hi! cl#" a

feQ ear! ago. 1ne da Qe had l#nch together and I e%$lained in detailQh h$erten!ion and fat acc#m#lation inthe "od are generall the con!e(#ence! of chronicall occ#rringdehdration. He acce$ted m ad&ice of increa!inghi! dail Qater intaYe. He al!o con&inced hi! Qife to ado$t the mea!#re./lea!e note the im$act of increa!ed QaterintaYe on allergie! and a!thma that ha&e "een !tated in the tQo letter!.Lt. Col. Salter B#rmei!ter ha! o"!er&ed the e[ect of Qater on hi! oQn"lood $re!!#re. A! o# can read in hi! letter,Qhich i! "eing $#"li!hed Qith hi! Yind con!ent, he, too, ha! e%$erienceda dr#g*free and nat#re*de!igned

adj#!tment to hi! "lood $re!!#re.If Qater i! a nat#ral di#retic, Qh do intelligent and a$$earing*to*"e*learned $eo$le !till in!i!t on #!ing chemical! toget rid of Qater from the Yidne! A! far a! I am concerned, thi! actioncon!tit#te! negligence. 0ince thi! action Qille&ent#all damage the Yidne!, and #ltimatel the heart, it! $ractice!ho#ld !to$.M colleag#e! Qho !till in!i!t on "lindl #!ing di#retic! in the treatmentof h$erten!ion are QalYing into fore!eea"lelitigation! for negligent treatment of their $atient!. 2he neQ informationQill $ro&ide their $atient! Qith !#\cient

in!ight to #nder!tand Qhat damage! ha&e "een ca#!ed in them " the!t#$id Qa of a!!erting the treatment of7h$erten!ion7 Qith di#retic!. Let the Fe"r#ar 5??9 cla!! action !#it of !moYer! again!t the to"acco ind#!tr "e ale!!on for the health care ind#!tr.LAS 1FFICE0 1F MICHAEL /A2URI0=85 N. LEE 02REE21LD 21SN ALEANDRIA, IRINIA ;;85=F. Batmanghelidj, M.D.Fo#ndation For 2he 0im$le In Medicine;5=@ King! arden Sa

Fall! Ch#rch, irginia ;;>=8Dear Dr. Batmanghelidj4I again Qi!h to thanY o# for o#r Yindne!! in hel$ing m Qife and me to"etter a$$reciate the im$ortance of Qaterto o#r health.Se feel the con!cio#! increa!e in o#r Qater con!#m$tion contri"#tedgreatl to o#r Qeight lo!! Z a Qeight lo!!

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Qhich had "een #rged #$on "oth of #! " o#r re!$ecti&e $h!ician! forear!. M lo!! of a$$ro%imatel fort*&e

=9G $o#nd! ha! re!#lted in !#ch a loQering of m "lood $re!!#re that Iam no longer taYing medicine for m "lood$re!ión.M QifeT! Qeight lo!! ha! alle&iated the di!comfort !he ha!e%$erienced for ear! Qith her "acY. enaddition, !he "elie&e! the Qeight lo!! ha! red#ced her di!comfort and$ro"lem! Qith her allergie!.Sith "e!t Qi!he!, I remainAtentamente,E. Michael /at#ri!8 A#g#!t 5??=F. Batmanghelidj, M.D.

Fo#ndation For 2he 0im$le In Medicine;5=@ King! arden SaFall! Ch#rch, irginia ;;>=8Dear Dr. Batmanghelidj40ince m ;= Ma 5??= letter, and o#r con!e(#ent tele$hone call, a$h!ical change of addre!! ha! a"!or"ed mtiem$o.2he neQ addre!! i! L2C Salter F. B#rmei!ter, 55: Ca!ita! delE!te, El /a!o, 2e%a! <??89.Al"eit, m#ch more im$ortant than the!e fact!, I am in a $o!ition to &erifhoQ ta$ Qater e[ecti&el loQer!la hi$erten!ión.0tarting in earl A$ril 5??=, lea&ing ear! of di#retic! and

calci#m*"locYer! "ehind, in accordance Qitho#r recommendation, for a$$ro%imatel 8 month! I dranY a minim#m of eight :*o#nce gla!!e! of ta$ Qaterocca!ionall more. 2he "lood $re!!#re, heretofore contained " dr#g!,grad#all dro$$ed from an a&erage aro#nd59>*5@> !!tolico&er ?9*?: dia!tolic to an amaing, dr#g free, 58>*589!!tolico&er <9*:> dia!tolic #ct#ating$romedio.M Qife maYe! the!e mea!#rement! at home each time taYing tQo orthree reading!. 2he record !hoQ! !e&eralloQ! of 5;>!. o&er <9d. and a rare high of 5=>!. o&er ?>d. HoQe&er, the

a&erage range, a! !tated a"o&e, #niformldominate!.In addition to &itamin! and mineral!, thi! dr#g*free a$$roach, "a!ede!!entiall on ta$ Qater and a $inch of !alt, ha!rela%ed m !!tem end j#!tie! the condence that o# hold thehandle! of a tr#l re&ol#tionar and mar&elo#!medical conce$t.

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0ince o# are a"o#t to $#"li!h a "ooY Qith a$$lica"le te!timonie! of theHdration 0!tem, m $er!onal e%$erience

i! gratef#ll o[ered a! a Qa of !aing thanY o#.Atentamente,HIHER BL11D CH1LE02ER1LHigher "lood chole!terol i! a !ign that the cell! of the "od ha&ede&elo$ed a defen!e mechani!m again!t theo!motic force of the "lood that Yee$! draQing Qater o#t thro#gh the cellmem"rane! or the concentrated "lood cannot relea!e !#\cient Qater to go thro#gh the cell mem"rane andmaintain normal cell f#nction!. Chole!terol i! anat#ral 7cla7 that, Qhen $o#red in the ga$! of the cell mem"rane, QillmaYe the cell Qall im$er&io#! to the $a!!age

of Qater !ee Fig#re 5=G. It! e%ce!!i&e man#fact#re and de$o!ition in thecell mem"rane i! $art of the nat#ralde!ign for the $rotection of li&ing cell! again!t dehdration. In li&ing cell!that $o!!e!! a n#cle#!, chole!terol i! theagent that reg#late! $ermea"ilit of the cell mem"rane to Qater. Inli&ing cell! that do not $o!!e!! a n#cle#!, thecom$o!ition of fatt acid! em$loed in the man#fact#re of the cellmem"rane gi&e! it the $oQer to !#r&i&edehdration and dro#ght.Chole!terol $rod#ction in the cell mem"rane i!a $art of the cell !#r&i&al !!tem. E! #nnece!!ar !#"!tance. It! e%ce!! denote! dehdration.

Normall, it i! Qater that in!tantl, re$eatedl, and tran!ientl form! intoadhe!i&e !heet! and "ind! the hdrocar"on"ricY! together. In a dehdratedmem"rane, thi! $ro$ert of Qater i!lo!t At the !ame time that Qater i! "inding the !olid !tr#ct#re of themem"rane, it al!o di[#!e! thro#gh the ga$! intothe cell.Fig#re 5= ha! "een de!igned to demon!trate the !tr#ct#re of a "ilaermem"rane d#ring f#ll hdration and it!$o!!i"le e%treme dehdration. I ha&e $re!ented thi! re!earched conce$tat an international gathering of cancerin&e!tigadore!.2he!e !ame !cientic !tatement! are $#"li!hed and ha&e

"een di!c#!!ed " other re!earcher!. cómodoe! thi! $henomenon a[ect #! in o#r e&erda life La re!$#e!ta e!!im$le.Imagine that o# are !itting at a ta"leand food i! "ro#ght to o#. If o#, do not drinY Qater "efore o# eat thefood, the $roce!! of food dige!tion Qill taYeit! toll on the cell! of the "od. Sater Qill ha&e to "e $o#red on the foodin the !tomach for $rotein! to "reaY and

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!e$arate into the "a!ic com$o!ition of their amino acid!. In the inte!tine,more Qater Qill "e re(#ired to $roce!! the

food ingredient! and then !end them to the li&er.In the li&er, the !$ecialied cell! Qill f#rther $roce!! the inte!tine*dige!ted material! and then $a!! the re!#$$liedand com$o!ition adj#!ted "lood to the right !ide of the heart. In theli&er, more Qater i! #!ed to $roce!! the foodingrediente!.2he "lood from the right !ide of the heart, Qhich ha! al!orecei&ed !ome 7fat7 com$onent! from thelm$hatic !!tem that em$tie! into the right !ide of the heart, Qill noQ"e $#m$ed into the l#ng! for o%genation ande%change of the di!!ol&ed ga!e! in the "lood. In the l#ng!, aeration of the "lood f#rther dehdrate! it " the $roce!!

of e&a$oration of QaterZthe 7Qinter !team.7NoQ thi! highl concentrated "lood from the l#ng! i! $a!!ed to the left!ide of the heart and $#m$ed into the arterialcirc#lación.2he r!t cell! that Qill face thi! highl o!moticallconcentrated "lood are the cell! lining the larger "lood&e!!el! and ca$illarie! of the heart and the "rain. Shere the arterie!"end, the o!moticall damaged cell! Qill al!oface the $re!!#re of the oncoming "lood. Here, the cell! Qill either needto $rotect them!el&e! or "ecomeirre&er!i"l damaged. Do not forget that the integrit of their cellmem"rane i! $ro$ortionatel de$endent on the

$re!ence of 7Qater7 that i! a&aila"le to them and not that Qhich i! "eingo!moticall $#lled o#t. A looY at Fig#re 59,and then Fig#re 5=, Qill maYe the #nder!tanding of thi! $roce!! of 7chole!terol ada$tation7 to dehdration ea!ier. 2here come! a moment Qhen the "rain "egin! to recognie the f#rtherim$o!ed !e&ere !hortage of Qater in the"od, and then in the middle of eating food Qill com$el the $er!on todrinY it. It i! alread too late, "eca#!e thedamage i! regi!tered " the cell! lining the "lood &e!!el!. HoQe&er,Qhen thi! dehdration regi!ter! it!elf "$rod#ction of the d!$e$tic $ain, Qe mo!t !t#$idl gi&e the $er!on

antacid Not Qater, antacid! Not Qater,hi!tamine*"locYing agent! Unfort#natel, thi! i! the $ro"lem Qith alltreatment $roced#re! #nder the 7!ol#te!$aradigm.7 All treatment $roced#re! are 7relief of !m$tom!7 oriented. 2he are not geared to the elimination of theroot ca#!e of the $ro"lem. 2hi! i! Qh 7di!ea!e!7 are not c#red. 2he areonl 7treated7 d#ring the lifetime of the$er!ona.

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 2he root ca#!e of degenerati&e di!ea!e! i! not YnoQn, "eca#!e a Qrong$aradigm i! "eing $#r!#ed. If Qe "egin to

a$$reciate that for the $roce!! of dige!tion of food, Qater i! the mo!te!!ential ingredient, mo!t of the "attle i! Qon.If Qe gi&e the nece!!ar Qater to the "od "efore Qe eat food, all the"attle again!t chole!terol formation in the"lood &e!!el! Qill "e Qon.After a longer $eriod of reg#lating dail Qater intaYe, !o that the cell!"ecome f#ll hdrated, grad#all thechole!terol defen!e !!tem again!t the free $a!!age of Qater thro#ghthe cell Qall Qill "e le!! re(#ired !#$rod#ction Qill decrea!e. 2he hormone*!en!iti&e, fat*"#rning enme! of the "od ha&e "een !hoQn to "ecome

acti&e after one ho#rT! QalY. 2he remain acti&e for 5; ho#r!. It al!o!eem! that Qith the loQering of "loodchole!terol and QalYing to ind#ce the 7fat "#rner!T7 acti&it, thede$o!ited chole!terol Qill al!o "e "roYen and$a!!age of "lood thro#gh the alread "locYed arterie! Qill "ecome$o!!i"le !ee Mr. Fo%T! letterG.SalYing tQo time! a daZe&er 5; ho#r!ZQill maintain the acti&it of the hormone !en!iti&e fat "#rning enmehormone !en!iti&e li$a!eG d#ring da and night and hel$ clear aQa thee%ce!! li$id de$o!it! in the arterie!. 2e!timonial! 2hat MaYe Oo# /onder

Mr. Mohammed Sah"T! concern i! not #ni(#e to him e&erone Qho ha!rai!ed "lood chole!terol le&el! i! Qorried.It i! common YnoQledge that man di!ea!e! are a!!ociated Qith rai!edchole!terol le&el! in "lood circ#lation.Di[erent "lood chole!terol le&el! ha&e in the $a!t "een con!iderednormalZall the time decrea!ing the acce$tedthre!hold #ntil aro#nd ;>> milligram! $er 5>> c#"ic centimeter! of "loodG i! noQ con!idered normal. Incl#!o e!tag#re i! an ar"itrar a!!e!!ment. I $er!onall "elie&e the normal rangeto "e aro#nd 5>> to 59>. M oQn le&el!!tarted aro#nd :? and ne&er Qent a"o&e 58>. Sh Beca#!e for ear!

and ear!, m da !tarted Qith tQo to threegla!!e! of Qater. In an ca!e, a March ;:, 5??5 NeQ England Jo#rnal of Medicine re$ort, folloQed " an editorial,a"o#t an ::*ear*old man Qho eat! ;9 egg! dail and ha! normal "loodchole!terol le&el!, re&eal! one fact. lachole!terol Qe eat !eem! to ha&e little to do Qith the high le&el of chole!terol in !ome $eo$leT! "lood.

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Let #! get one thing clear4 E%ce!! chole!terol formation i! the re!#lt of dehdration. It i! the dehdration that ca#!e!

man di[erentdi!ea!e! and not the le&el of chole!terol in the circ#lating "lood. It I!therefore more $r#dent to attend to o#r dailQater intaYe rather than to Qhat food! Qe eat. Sith $ro$er enmeacti&it, an food can "e dige!ted, incl#ding it!chole!terol content. Mr. Sah" co#ld red#ce hi! chole!terol le&el!Qitho#t too m#ch an%iet a"o#t hi! food intaYe!ee letter on $age ?>G.He li&ed normall and et hi! chole!terol le&el! came doQn dramaticallfrom ;<? to ;>8 in tQo month! Qitho#t anfood limitation!. All he had to do Qa! to drinY more Qater "efore hi!

meal!. If he had taYen reg#lar dail QalY!, thi!le&el Qo#ld ha&e "een f#rther red#ced d#ring the tQo month!. In time, itQill "e f#rther red#ced. Hi! te!timonial i!$rinted " hi! Yind $ermi!!ion. He i! !o ha$$ Qith the !im$licit of the$roce!! that he Qi!he! to !hare hi! jo Qithotro!.If increa!ed Qater intaYe loQer! chole!terol le&el!, onl to ri!e again,maYe !#re o#r "od i! not getting !hort of!al.Read the !ection on !alt in cha$ter 5;. Oo# !ho#ld realie thatchole!terol i! the "a!ic "#ilding "locY for mo!thormone! in the h#man "od. Nat#rall, a "a!ic dri&e for increa!ed

hormone $rod#ction Qill al!o rai!e the rate ofchole!terol $rod#ction.Ba!icall, it i! a!!#med that heart di!ea!e "egin! Qith the de$o!it of chole!terol $la(#e! in the arterie! of the heart.At the nal !tage!, the tQo ma e%i!t at the !ame time. HoQe&er, in mo$inion, it "egin! Qhen the con!triction$rod#cing chemical! from the l#ng! !$ill o&er into the circ#lation thatgoe! to the heart. A! it i! e%$lained in thecha$ter on a!thma, in dehdration, $art of the $roce!! of Qater$re!er&ation i! the a!!ociated !ecretion of!#"!tance! that con!trict the "ronchiole!. At a certain thre!hold that

doe! not at the time manife!t it!elf in ana!thma attacY, the !ame chemical!, if the !$ill into the "lood circ#lationthat goe! thro#gh to the l#ng, Qill al!ocon!trict the Qall! of the heart arterie! once the reach them. 2hi!!it#ation Qill lead to heart $ain!, YnoQn a!anginal $ain!.EMBA00O 1F 2HE ARAB RE/UBLIC 1F EO/2/RE00 ^ INF1RMA2I1N BUREAU

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5@@@ C1NNEC2ICU2 AENUE. N.S.0UI2E ==>SA0HIN21N. D.C. ;>>>

Ma 5!t, 5??5Dr. Feredoon BatmanghelidjFo#ndation For 2he 0im$le In Medicine/.1 Bo% 8;@<, Fall! Ch#rch, A ;;>=8Dear Dr. Batmanghelidj, 2hi! i! to !a hoQ gratef#l I am to o# for maYing me a m#ch le!!Qorried man. I ha&e !#[ered from a highchole!terol le&el !ince 5?:;. It Qa! ;<: Qhen it Qa! r!t di!co&ered. IQa! then in erman and I Qa! $#t on !#ch a!trict diet that I lo!t 5@ $o#nd! in le!! than tQo month! and theChole!terol le&el Qent doQn to onl ;;>. I ref#!ed to

acce$t to loQer it f#rther thro#gh medication e!$eciall !ince in Eg$tthe doctor! !till "elie&e that thi! le&el i! notreall dangero#! " the $re&ailing !tandard! in o#r co#ntr.0ince I entertain and attend "#!ine!! l#nche! more than Qhat Qo#ld "ee%$ected e&en from a di$lomat, "eca#!e ofthe additional "#rden of dealing Qith the media, m chole!terol Qa!alQa! going #$ to aro#nd ;@> and "acY to;;>!, " $#tting m!elf on &er !trict diet from time to time. HoQe&er, itm#!t "e noted that it Qa! onl o#t!ide mhome that the diet came cra!hing doQn. 1therQi!e, Qa! !trict Qithm!elf. In fact, e&en Qhen I ate o#t!ide, I Qa!

caref#l to choo!e di!he!, Qhere&er a&aila"le, Qhich Qere not $artic#larlrich in fat.La!t ear I Qa! !hocYed to di!co&er that m "lood chole!terol le&el had!hot #$ to ;<?. I Qa! l#cY to ha&e met o#a contin#ación.Shen o# 7$re!cri"ed7 am$le Qater tQo f#ll gla!!e!G "etaYen "efore meal! in!tead of medication that I Qa! j#!t a"o#t to !#"mit m!elf to then, I Qa! &er !Ye$tical.All the more !o!ince o# did not o&erem$ha!ie dieting. entQo month!, and Qith &er little o"!er&ance of all the old 7r#le!T QhichQere maYing m life mi!era"le, m chole!terolQent doQn to ;>8 for the r!t time in more than nine ear! MO Qeight

too Qa! !#r$ri!ingl al!o doQn " a"o#t eight$o#nd! and ha! !ince "een #nder control. In fact, I feel !o good that I am!#re that the ne%t time I Qill "e going for a"lood te!t, m chole!terol le&el Qill "e fo#nd to "e e&en loQer. 0o,good"e to the 7normal7 Eg$tian !tandard! andQelcome to the American neQ le&el! of chole!terol Qitho#t theaccom$aning !en!e of de$ri&ation

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Enjoing eating, moderatel of co#r!e, a! I had not "een doing for a longtime and free from a Qorr that Qa!

alQa! at the "acY of m mind, I "elie&e I oQe o# a "ig 2HANK O1U.t#o !inceramenteMINI02ER M1HAMMED SAHBODirector, /re!! and Information B#rea# 2he!e !ame chemical! can al!o !et the !tage for the de$o!it of chole!terol in the Qall! of the arterie!. El com-nfactor to all of the &ario#! condition! la"eled a! di[erent di!ea!e! of theheart and the l#ng! i! an e!ta"li!hedla de!hidratación.2aYe a looY at Mr. 0am Lig#oriT! letter, $#"li!hed " hi!Yind $ermi!!ion.Hi! anginal $ain di!a$$earedQhen he !tarted to increa!e hi! Qater intaYe. He al!o ha! !#[ered from

hiat#! hernia. 2hat, too, ha! !tarted to deararri"a.i&e him time, and it Qill reco&er com$letel.Al!o taYe a looY atLoretta John!onT! letter. U!ted &er) (#e incl#!oat the o#ng*at*heart age of ?>, her anginal $ain can "e treated QithQater to the e%tent that !he doe! not need anmedication for her heart $ain!.I ha&e man, man letter! !imilar to the!e. It i! not $o!!i"le to $#"li!hthem all. I ha&e !elected a feQ of them to!hoQ o# that Qhat I $ro$o!e i! not a theor. It, in fact QorY! fordi[erent $eo$le of &aring age!.SARD

 2he 2alY 0tation599 >*AMDecem"er ;, 5??=lo"al Health 0er&ice, Inc.Dr. Feredoon BatmanghelidjFo#ndation For 2he 0im$le In Medicine/.1 Bo% 8;@<, Fall! Ch#rch, A ;;>=8Dear Dr. Batmanghelidj4 J#!t a !hort letter to thanY o# for informing o#r li!tener! a"o#t thehealth "enet! of drinYing tQo (#art! of Qater ad+a.

Not onl did o# hel$ o#r radio a#dience, "#t I $er!onall ha&e enjoeda re!#rgence of energ after drinYing tQo(#art! of Qater each da for j#!t o&er one QeeY. 2he angina $ain I end#red for &e ear! ha! di!a$$eared and mdi!tre!! from a hiatal hernia ha! greatl le!!ened.I feel liYe a neQ $er!on.IT&e "een doing talY !hoQ! at SARD Radio for the $a!t ;> ear!, and Im#!t !a o#r inter&ieQ Qith #! i! one ITll

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rec#erde !iem$re.Atentamente,

0am#el M. Lig#ori, /rogram DirectorSARD Broadca!ting Cor$oration/.1 Bo% 599> /itt!ton, /A 5:@=> <5<G @99*99;5Mr. John Fo%T! ca!e i! &er #n#!#al in that hi! !e&ere ca!e of heartdi!ea!e Qa! re&er!ed !#\cientl to maYe lifeonce again normal for himZQitho#t the "$a!! !#rger that i! noQ in&og#e. Mr. Fo% i! in hi! !i%th decade of life.He i! a retired electronic! engineer Qho ha! !$ent man highlre!$on!i"le ear! Qith the Na&. 2oda, he i! one ofthe 9> li&ing Bate!*2rained Nat#ral 7i!ion !$eciali!t!. At !ome $oint intime, he Qa! nearl "lind in one ee and

lo!ing &i!ion in the other. He "ecame intrig#ed Qith the Bate! method of &i!ion training "eca#!e of hi! oQn need!.A! a re!#lt of hi! training, he i! not going "lind anmore and hi! ee!ighti! !a&edZ&irt#all normal noQ.A feQ ear! "acY, he Qa! con!idered h$erten!i&e.He recei&edmedication to red#ce hi! "lood $re!!#re. l $odr+anot taYe the medication! the made him Qor!e. Hi! $ro"lem! !tartedQhen he !#[ered hi! heart attacY!. Hi! lettere%$lain! Qhat ha$$ened to him and hoQ he i! "etter noQ. 2he highlightof thi! letter i! that after tQo month! oftaYing increa!ed Qater, and a !light adj#!tment to hi! diet, in addition to

hi! dail QalY!, hi! coronar arterie! m#!tha&e cleared !#\cientl for him to feel normal. He noQ enjo! normalacti&it Qitho#t ha&ing to end#re an $ain,and all of that Qitho#t the #!e of an medication or !#[ering "*$a!!!#rger.Imagine that a $er!on Qith !#ch a !e&ere heart $ro"lem a! Mr. Fo% co#ldin a"o#t tQo month! get "acY to normallife and not need in&a!i&e treatment e&en tho#gh chemical treatment!failed 2he $ro$o!ed nat#re*de!igneda$$roach to the $ro"lem !cienticall and logicall !eem! to de$end on$h!iological re&er!al of the di!ea!e

$roce!o.ItT! an ideal Qa of o[ering c#re! for !ome degenerati&e di!ea!econdition!.BA2E0*F1Nat#ral i!ion 2raining;?=9 North Le%ington 0treetArlington irginia ;;;>< 2ele$hone <>8 98@ <=:;Atte!tation4 ;9 March 5??;

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It Qa! in the !$ring of 5??5 Qhen I r!t learned from a mem"er of theFo#ndation For the 0im$le In Medicine the

&al#e of Qater a! a form of medication. 0i% month! "efore, I had !#[eredtQo heart attacY! and had #ndergoneangio$la!t !#rger. After the o$eration, I Qa! $re!cri"ed hea& do!age!of calci#m and "eta "locYer!, "a"a!$irin, nitroglcerine for $ainG, and chole!terol*red#cing medicine forreco&er. 2he angiogram "efore theangio$la!t had !hoQn one of the arterie! of m heart Qa! ?< $ercent"locYed " chole!terol de$o!it!. I Qa! told mheart had "een damaged.After !i% month! of !trict attention to m $re!cri"ed 7rec#$eration7$rogram, I noticed that m condition Qa! ra$idl

deteriorating, to the e%tent that I had di\c#lt !lee$ing "eca#!e of $ainin m left arm, "acY and che!t, and al!o feltthe!e !ame $ain! Qhen I tooY m dail QalY!. I &i!#alied m!elf goingfor "$a!! !#rger at the !ched#led time forree&al#ation of m condition. B thi! time, I al!o !#[ered from !erio#!!ide e[ect! ca#!ed " the medication!, !#cha!4 m $ro!tate created retention and "locYing $ro"lem! I had al!ode&elo$ed $ro"lem! Qith m &i!ion andmemor recall.I r!t "egan m reha"ilitation thro#gh diet " a reg#lar intaYe of !i% toeight :*o#nce gla!!e! of Qater each da for

tre! d+a!.I Qa! told to drinY Qater a half*ho#r "efore eating m dailmeal!.I c#t o[ m anti*chole!terol $ill!,a!$irin and nitroglcerine $ill!. J#dging " the e[ect of the Qater, it!eemed I did not need them. I al!o !tarted taYingorange j#ice and !tarted #!ing !alt in m diet again I had "een on a!odi#m*free dietG. After the r!t three da!, IQa! feeling more comforta"le a"o#t all of that added Qater. After threeQeeY! of grad#all red#cing the calci#m and"eta*"locYer!, I noticed !ome &er fa&ora"le change!. Shene&er I felt$ain, I Qo#ld drinY Qater and get in!tantali&io.M diet remained the !ameZfr#it!, &egeta"le!, chicYen, !h,

orange j#ice, and carrot j#ice.2o get moretr$to$han, I Qa! a!Yed to add cottage chee!e and lentil !o#$ to mdiet.Dr. Batmanghelidj re(#e!ted that I taYe tQo one*ho#r QalY! ;9 min.mileG a da. After the !econd month, I noticedno more $ainZe&en QalYing #$ !tee$ hill!. After the fth month, Ichanged m QalY! to 5; ho#r and increa!ed m

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$ace to a 59*min#te mile. No con!triction! Qere noticed d#ring m QalY!and m energ had increa!ed tQo*fold.

M#ch of m $oQer to recall had "een ree!ta"li!hed, and m &i!ionret#rned to normal.In 1cto"er 5??5, I had a !erie! of chemical and $h!ical te!t!, incl#ding%*ra!, !onogram, echocardiogram andelectrocardiogram, to determine the !tate of m heart. 2he te!t! !hoQedthat m heart had re!tored to it! normal!tate and I did not need an form of medication to co$e Qith m dailro#tine. M doctor co#ld not "elie&e hoQ!im$l all thi! change had taYen $lace. John >. Fo%Bate!*Fo% Nat#ral i!ion 2raining

Adding the !tatement! of Mr. Sah" to the re!#lt! $re!ented " Mr. Fo%,Mr. /at#ri!, Mr. Lig#ori, Mr!. John!on,Col. B#rmei!ter and Mr. /ecY, one "egin! to recognie the fact thatcommon ta$ Qater ha! medicinal &al#e!hitherto #nrecognied. Sater i! a readil a&aila"le nat#ral medicine for!ome of the $re&alent and &er !erio#!medical condition! that are YnoQn to Yill man tho#!and! of $eo$lee&er ear. I! it heart di!ea!e or dehdrationthat i! Yilling $eo$le In m $rofe!!ional and !cientic &ieQ, it i!dehdration that i! the "igge!t Yiller, more than another condition o# co#ld imagine. 2he di[erent a!$ect! and 7chemical

idio!ncra!ie!7 of each indi&id#alT! "odreaction to the !ame $attern of dehdration ha&e recei&ed di[erent$rofe!!ional la"el! and ha&e "een treateddi[erentlZand ine[ecti&el.Dehdration i! the common factor. It i! the di[erence in the 7chemical"l#e$rint7 in the de!ign of each "od thatinitiall demon!trate! the !ign! of chronic dehdration " di[erento#tQard indicator!. Later in the $roce!!, otherindicator! of the !ame dehdration "ecome a$$arent. 2he rea!on for thi!di[erence in the initial $attern ma Qell "ethe !electi&e $roce!! of 7!hoQer*head7 emergenc hdration of !ome

cell t$e! in the "od. If o# taYe a !econdlooY at the letter! " Mr. /ecY, Mr. /at#ri! and Mr. Silliam ra $age59;G, o# Qill !ee that the indi&id#al! in(#e!tion had m#lti$le $ro"lem! that got "etter " the reg#lation of dailQater intaYe. Oo# are noQ $ri& toinformation on Qhere the mi!taYe lie! in the creation of mon!tro#!$ro"lem! Qithin the health care !!tem! in

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!cienticall ad&anced co#ntrie!. 2he !eem to alloQ the arroganttreatment of a !im$le dehdration of the h#man

"od " chemical mallet! #ntil real di!ea!e! are "orn.ECE00 B1DO SEIH272he !ecret of caring for a $atient i! caring for the $atient.70ir Silliam 1!ierP4 Sh are 8> $ercent of American! o&erQeight A4 Beca#!e of a mo!t"a!ic conf#!ion 2he donTt YnoQ Qhen the are thir!t the al!o donTt YnoQ thedi[erence "etQeen 7#id!7 and 7Qater.7Let #! di!c#!! the letter! from Mr. /ecY, Mr. /at#ri!, /ri!cilla /re!ton, andDonna #tYoQ!Yi that folloQ. 2odo!!tated the lo!t "etQeen 8> and =9 $o#nd! in Qeight Qhen the

!Qitched to Qater a! their $referred "e&erage. 2here i! another $er!on Qho grad#all lo!t 9: $o#nd! in le!! than aear, Qeight !he had gained in !i% ear!. comoo# read on, o# Qill !ee hoQ !im$l Qe gam Qeight. Oo# Qo#ld thinY it7!im$li!tic7 if o# did not ha&e the $roof infront of o#. 2he central control !!tem in the "rain ha$$en! to recognie the loQenerg le&el! a&aila"le for it! f#nction!. la!en!ation! of thir!t or h#nger al!o !tem from loQ, read*to*acce!!energ le&el!. 2o mo"ilie energ from thatQhich i! !tored inthe fat, one need! hormonal relea!e mechani!m!. 2hi!

$roce!!taYe! a Qhile longer and !ome$h!ical acti&it for energ relea!eG than the #rgent need! of the "rain. 2he front of the "rain either get! energ from7hdroelectricit7 or from !#gar in "lood circ#lation. It! f#nctional need!for hdroelectricit are more, #rgentZnotonl the energ formation from Qater, "#t al!o it! tran!$ort !!temQithin the micro!tream oQ !!tem that de$end!on more Qater. 2h#!, the !en!ation of thir!t and h#nger are generated !im#ltaneo#!l toindicate the "rainT! need!. No!otro! no hacemo!recognie the !en!ation of thir!t and a!!#me 7"oth indicator!7 to "e the

#rge to eat Se eat food e&en Qhen the"od !ho#ld recei&e Qater. In the!e $eo$le Qho lo!t Qeight, " drinYingQater "efore eating food, the managed to!e$arate the tQo !en!ation!. 2he did not o&ereat to !ati!f an #rge forthe intaYe of Qater.1&ereating F#rther E%$lained 2he h#man "rain i! ro#ghl 5 9>th of the total "od Qeight. It i! !aid to$o!!e!! a"o#t nine trillion ner&e cell!

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com$#ter chi$!G. Brain cell! are !aid to "e :9 $ercent Qater. 2Qent$ercent of "lood circ#lation i! allocated and

made a&aila"le to the "rain. 2hi! mean! that the "rain get! to $icY andchoo!e from the circ#lating "lood Qhat i!needed for it! normal f#nction!. 2he "rain i! the onl $art of the "odthat i! con!tantl acti&e. It $roce!!e! allinformation from di[erent $art! of the "od, a! Qell a! that Qhich enter!it from dail e%$o!#re to $h!ical, !ocial,and electromagnetic en&ironment. 2o $roce!! all the!e in$#t! and alert all $art! of the "od for coordinatedre!$on!e, the "rain !$end! a &a!t (#antitof energ. At the !ame time, it !$end! energ in man#fact#ring $rimaringredient! and di[erent "rain chemical

me!!enger! ne#rotran!mitter!G that are made in the "rain cell! andha&e to "e tran!$orted to the ner&e ending!Qhere&er the are. 2he tran!$ort !!tem #!e! a &a!t (#antit of energ. 2hi! high rate of energ con!#m$tion "the "rain i! the main rea!on Qh it recei&e! a"o#t ;> $ercent of "loodcirc#lation.Brain cell! !tocY$ile energ in tQo main form!4 A2/ and 2/ re!er&e!ZliYe the coal and coYe d#m$! ne%t to$oQer $lant!. Certain action! are !#$$lied Qith energ from A2/!tocY$ile! that are located in di[erent $art! of thecell, mainl Qithin it! mem"rane!. 2he cell mem"rane i! Qhere the

information enter! and Qhere an action i!initiated. 2here i! a !!tem of energ rationing in o$eration in each cell.Not all !tim#lation Qill achie&e an allocationof energ from the A2/ !tocY$ile to get regi!tered and in&oYe are!$on!e. 2here i! a thre!hold for energ relea!e for !ome 7in$#t!.7 2he "raincalc#late! and #nder!tand! Qhat i! im$ortantand Qhat i! not for it! energ e%$endit#re.Shen A2/ re!er&e! are loQ,man !tim#li do not in&oYe a re!$on!e. e!teloQ A2/ re!er&e in !ome o&eracti&e "rain cell! Qill "ecome reected a! afatig#e !tate in f#nction! controlled "

tho!e "rain cell!. E%actl the !ame $roce!! i! in o$eration for the 2/!tocY$ile!. In certain emergenc action!,!ome energ from 2/ !tocY$ile can "e di&erted to "oo!t the A2/!tocY$ile to !#!tain !ome of the mo!t e!!entialf#nction! that Qo#ld otherQi!e !#[er from lacY of local energ.0torage of energ in the "rainT! energ $ool! !eem! to rel hea&il onthe a&aila"ilit of !#gar. 2he "rain i!

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con!tantl draQing from the "lood !#gar to re$leni!h it! A2/ and 2/!tocY$ile!. Recentl it ha! "een di!co&ered

that the h#man "od ha! the a"ilit to generate hdroelectric energQhen Qater, " it!elf, goe! thro#gh the cellmem"rane and t#rn! !ome &er !$ecial energ generating $#m$! &erm#ch liYe the hdroelectric $oQergeneration Qhen a dam i! "#ilt on a large ri&er. 2h#!, the "rain #!e! tQomechani!m! for it! energ re(#irement!41ne, from meta"oli!m of food and formation of !#gar4 tQo, from it!Qater !#$$l and con&er!ion of hdroelectricenerg+a.It noQ !eem! that the "rain de$end! &er e%ten!i&el on energformation from 7hdroelectricit,7$artic#larl for it! tran!$ort !!tem in it! ner&e !#$$l to di[erent $art!

of the "od. 2o !ati!f the "rainT! re(#irement!, the h#man "od ha! de&elo$ed a&er delicate "alancing !!tem to Yee$ anormal range of !#gar concentration in the "lood. Itdoe! thi! in tQoQa!. 1ne, " !tim#lating the intaYe of $rotein!and !tarch food! that it Qill con&ert to !#gar, in addition to the !#gar inthe diet tQo, " con&erting !ome !tarch and$rotein! from !tored re!er&e! of the "od into !#gar.2hi! lattermechani!m i! called 7gl#co*neo*gene*!i!.7 E!to !ignicaremaYing of !#gar from other material!. 2hi! re*man#fact#ring of !#garfor #!e " the "rain i! done in the li&er.

 2he de$endence of mo!t "rain f#nction! on energ from !#gar ha!de&elo$ed a !atiet or $lea!#re a!!ociation forthe !Qeet ta!te. It ha! e!ta"li!hed a certain coding !!tem forcoordination of f#nction! " the other organ!,$artic#larl " the li&er Qhen !Qeet ta!te !tim#late! the tong#e. Shenthere i! not eno#gh !#gar in circ#lation, theli&er "egin! to man#fact#re it and con!tantl to$! #$ "lood le&el! " theaddition of more !#gar. At the "eginning, itQill con&ert !tored !tarch, folloQed " $rotein! and !mall (#antitie! of fat. Fat con&er!ion i! a &er !loQ $roce!!. 2he "od need! to go Qitho#t food for !ome time "efore a higher rate of 

fat meta"oli!m i! e!ta"li!hed. La! $rote+na! !onmore acce!!i"le and "roYen doQn more ea!il than fat. Fat de$o!it! aremade #$ of man !ingle #nit! of 7fattacid!7 joined together. It i! the indi&id#al fatt acid! that are "roYen fortheir energ &al#e. Each gram of fat gi&e!nine calorie! of energ. Each gram of $rotein or !#gar $ro&ide! onl fo#rcalorie! of energ. 2hi! i! the rea!on,Qhen fat i! meta"olied, a $er!on i! far le!! h#ngr.

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In children, fat !tore! are "roQn in color and ha&e m#ch "lood circ#lationin them. In "roQn fat, fat i! meta"olied

directl and heat i! generated. In later ear! of life, fat !tore! ha&e le!!"lood circ#lation and are le!! acce!!i"le tothe enme! that Qo#ld mo"ilie the fatt acid! for con&er!ion in theli&er and the m#!cle!. Shen m#!cle! areinacti&e, the are more ea!il attacYed and their $rotein i! "roYen doQnfor con&er!ion into !#gar. 0in em"argo, !im#!cle! are #!ed, the "egin to meta"olie !ome of their !tored fat a! achoice !o#rce of energ to do QorY andmaintain or increa!e their "#lY 2o do thi!, the "egin to acti&ate a fat*"reaYing enme called 7hormone !en!iti&eli$a!e.7 It ha! "een !hoQn in re$eated "lood te!t! in 0Qeden that thi!

enmeT! acti&it i! !een after one ho#rT!QalY and retain! it! fat*"reaYing acti&it for 5; ho#r!. 1nce m#!cle!"egin to #!e fat, more !#gar Qill "ecomea&aila"le to "e #!ed " the "rain.Sith re$eated QalY!, acti&it of the fat*"#rning enme! "ecome m#chmore $rono#nced. 2h#!, a com$onent ofan dieting $rogram !ho#ld "e m#!cle #!e for it! long*la!ting, $rimarand direct $h!iological e[ect on fat"reaYdoQn. It i! thi! enme in "lood circ#lation that Qill al!o clean all"lood &e!!el Qall! of fatt $la(#e! andde$ó!ito!.It Qa! thi! $h!iological re!$on!e of the "od to QalYing that

re&er!ed the health $ro"lem! of Mr. JohnFo%.Increa!ed Qater intaYe ga&e him energ and !tamina and QalYing!tim#lated the enme! that cleared hi!arterie!.1\ce QorY and de!Y jo"! in o#r modern Qa of life are onl a c#lt#raltran!formation. 2he "od $h!iolog ha! notet tran!formed !#\cientl to accommodate for thi! f#nctionalla"normal #!e of the h#man "od. 2he h#man "od!till need! m#!cle acti&it to maintain normal f#nction!. If the "odf#nction! normall, it Qill YnoQ Qhen to eat andhoQ m#ch to eat Qitho#t !toring fat. E&er $art of the "od Qill #!e it!

!hare of energ !#$$l for e\cient and Qell*coordinated f#nctioning. 2hi! i! Qhat it i! de!igned for.HoQe&er, if the "rain i! #!ed more in time! of !tre!!G and the "od i!not #!ed $ro$ortionatel to !#$$l the "rainQith it! !#gar need!, a le!!*di!ci$lined $er!on Qill gi&e in to eating moreoften and in larger (#antitie!. 0e con&iertemore dramatic if one doe! not recognie the other thir!t !ignal! of theh#man "od Qhen it need! Qater for it!

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energ !#$$l, Qhen in $lace of drinYing Qater " it!elf more food i!con!#med. In !tre!!, the "od "ecome!

de!hidratado.2he rea!on Qe tend to gain Qeight i! one !im$le fact4 Qeeat to !#$$l the "rain Qith energ for it!con!tant ro#nd*the*clocY acti&it.HoQe&er, Qhen food i! eaten, onla"o#t ;> $ercent of it reache! the "rain. lare!t Qill grad#all "ecome !tored if m#!cle acti&it doe! not #!e #$ it!allocated $ortion. Sith Qater a! a !o#rce ofenerg, thi! !torage doe! not ha$$en. E%ce!! Qater i! $a!!ed o#t in theform of #rine.Diet 0oda! Can Ca#!e Seight ainM o"!er&ation ha! "een that diet !oda! all &ariet of man#fact#red!oft drinY! are called !oda in!tead of #!ing the

la"el on the drinYG, e&en tho#gh containing no a$$recia"le n#m"er of calorie!, are $o!!i"l the ca#!e of moreQeight gain in $eo$le Qho re!ort to taYing them to control their Qeight.1ne $er!on !tand! o#t4 A o#ng man in hi!tQentie!, a"o#t 9T 97 in height. laYe mo!t college !t#dent!, he #!ed todrinY reg#lar !oda! Qhile #nder con!tant$re!!#re for com$letion of hi! !t#die!. He had alread gained e%ce!!Qeight " the time he grad#ated.After grad#ation, to red#ce Qeight, he "egan drinYing eight can! of diet!oda! $er da. In a"o#t tQo ear!, he m#!tha&e gained another 8> $o#nd!. He !eemed to get a! ro#nd a! he Qa!

tall. Hi! QalY "ecame di\c#lt, and he!eemed to ha&e to !Qing hi! hi$ to taYe a !te$. He al!o dranY hi! diet!oda at mealtime! and ate more than hi!"od needed. He !till con!#me! hi! diet !oda!Zhe !eem! to "e addictedZand, de!$ite all other e[ort!, contin#e!to "e o&erQeight. 2hi! $arado% in o#r #nder!tanding of the relation!hi$ "etQeen taYing a!Qeetener that doe! not directl contri"#te tothe total calorie intaYe of the "od and Qeight gain need! e%$lanation. 2he folloQing i! the re!#lt of m re!earch intothi! enigma. 2here are man !#ch $er!on! Qho re!ort to taYing diet

!oda! and, in!tead of lo!ing Qeight, the "eginto gain it. 2he tran!cri$t of a te!timonial from Donna #tYoQ!Yi, Qho forear! onl con!#med !oda! and !teadilgained Qeight regardle!! of anthing el!e !he did to !hed the e%ce!!$o#nd!, Qill al!o folloQ.In America in 5:9>, a"o#t 58 o#nce! of !oda Qere con!#med $er $er!on$er ear. In the late 5?:>!, more than 9>>tQel&e*o#nce can! of !oda! Qere con!#med $er $er!on $er ear.

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 2he conf#!ion that all man#fact#red "e&erage! Qill !#$$l the "od Qithit! dail Qater need!, more than an other

ca#!e, i! re!$on!i"le for !ome of the di!ea!e! that Qe enco#nter. ro!!di!g#rement of the "od " fat collectioni! the initial !te$ in the decline of the h#man "od, and in m o$inion i!ca#!ed " the Qrong choice of #id! intaYe.0ome of the!e "e&erage! do more damage than other!.Ca[eine, one of the main com$onent! of mo!t !oda!, i! a dr#g. It ha!addicti&e $ro$ertie! "eca#!e of it! directaction on the "rain. It al!o act! on the Yidne! and ca#!e! increa!ed#rine $rod#ction. Ca[eine ha! di#retic$ro$iedade!.It i! $h!iologicall a dehdrating agent.2hi! characteri!tici! the main rea!on a $er!on i! forced to drinY

!o man can! of !oda e&er da and ne&er "e !ati!ed.2he Qater doe!not !ta in the "od long eno#gh. al!ame time, man $er!on! conf#!e their feeling of thir!t for Qater. 2hinYing the ha&e con!#med eno#gh 7Qater7 thati! in the !oda, the a!!#me the are h#ngr and "egin to eat more thantheir "odT! need for food. /or lo tanto,dehdration ca#!ed " ca[eine*containing !oda!, in d#e time, Qill ca#!ea grad#al gain in Qeight from o&ereating a!a direct re!#lt of conf#!ion of thir!t and h#nger !en!ation!.Ca[eine ha! 7$icY*me*#$7 $ro$ertie!.It !tim#late! the "rain"od e&enQhen a $er!on i! e%ha#!ted /arece (#e

ca[eine loQer! the thre!hold of A2/ !tocY$ile control. 0tored A2/ i! #!ed#$ for !ome f#nction! that Qo#ld notnormall gain acce!! to it Qhen there i! a !et le&el of re!er&e!.Shen !oda! contain !#gar, at lea!t !ome of the "rainT! need for !#gar i!!ati!ed. If ca[eine i! relea!ing A2/energ to enhance $erformance, at lea!t it! !#gar com$anion Qillre$leni!h !ome of the lo!t A2/, e&en if the nalre!#lt i! a decit e%$endit#re of A2/ " the "rain.In earl 5?:>!, a neQ $rod#ct Qa! introd#ced into the "e&erage ind#!trZan articial !Qeetener other than!accharin. It i! called a!$artame. A!$artame i! 5:> time! a! !Qeet a!

!#gar Qitho#t an calorie o#t$#t. It i! noQ incommon #!e "eca#!e the Food and Dr#g Admini!tration /DAG ha!deemed it !afe to #!e in $lace of !#gar. En #na&er !hort $eriod of time, it ha! "een incor$orated in o&er 9>>> reci$e!.In the inte!tinal tract, a!$artame con&ert! to tQo highl e%citatorne#rotran!mitter amino acid!4 a!$artate and$henlalanine, a! Qell a! methl alcoholformaldehdeZQood alcohol. Iti! claimed the li&er render! methl alcohol

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non*to%ic. I $er!onall thinY thi! claim i! made to "r#!h a!ide &oicedo"jection! for commercialiation of a

man#fact#red 7food7 that ha! a YnoQn to%ic "$rod#ct.If ca[eine con&ert! A2/ to AM/, a !$ent energ 7a!h,7 a!$artate con&ert!2/ energ !tocY$ile to M/. Both AM/and M/ are !$ent f#el! the ca#!e thir!th#nger to re$lace the lo!t f#el!tocY$ile! in the "rain cell!. 2h#!, diet!oda! ca#!e indi!criminate o&er#!e of energ re!er&e! of cell! in the"rain.It i! a Qell*recognied, !cientic fact that !$ent f#el AM/G doe! ca#!eh#nger. Ca[eine ca#!e! addiction, and$eo$le Qho con!#me it on a reg#lar "a!i! !ho#ld "e a!!#med to "e7!odaholic!.7 Hence, ca[einated diet !oda! in

!edentar $er!on! m#!t ca#!e Qeight gain the indirectl !tim#latemore food intaYe "eca#!e of the "rainT! forced#!e of it! energ re!er&e!. Bear in mind that onl !ome of the energ&al#e of food! eaten Qill "e #!ed " the "rain. 2he re!t of the con!#med energ Qill "e !tored in the form of fat if not#!ed " m#!cle acti&it. 2hi! Qeight gain i!one of man re!#lt! of diet !oda con!#m$tion. 2he more im$ortant ree% that occ#r! i! a "rain reaction to !Qeet ta!te. 2he jargon #!ed i! 7ce$halic $ha!ere!$on!e.7 A conditioned ree% "ecome! e!ta"li!hed a! a re!#lt of life*long e%$erience Qith !Qeet ta!te that i!

a!!ociated Qith the introd#ction of neQ energ into the "od. Shen!Qeet ta!te !tim#late! the tong#e, the "rain$rogram! the li&er to $re$are for acce$tance of neQ energZ !#garZfrom o#t!ide. 2he li&er, in t#rn, !to$! theman#fact#re of !#gar from the $rotein and !tarch re!er&e! of the "odand in!tead "egin! to !tore the meta"olicf#el! that are circ#lating in the "lood. A! Michael . 2ardo[, MarY I.Friedman, and other !cienti!t! ha&e !hoQn,ce$halic $ha!e re!$on!e! alter the meta"olic acti&it in fa&or of n#trient!torage the f#el a&aila"le for con&er!ion i!red#ced Qhich lead! to the de&elo$ment of a$$etite.

If it i! indeed !#gar that !tim#late! the re!$on!e, the e[ect on the li&erQill "e the reg#lation of that Qhich ha!entered the "od.HoQe&er, if !Qeet ta!te i! not folloQed " n#trienta&aila"ilit, an #rge to eat Qill "e the o#tcome. loi! the li&er that $rod#ce! the !ignal! and the #rge to eat 2he more !Qeetta!te Qitho#t the accom$aning calorie!that !tim#late! the ta!te "#d!, the more there i! an #rge to eatZo&ereat.

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 2he e[ect of ce$halic $ha!e re!$on!e to !Qeet ta!te ha! "een dearl!hoQn in animal model! Qith the #!e of

!accharin. U!ing a!$artame, !e&eral !cienti!t! ha&e !hoQn a !imilar #rgeto o&ereat in h#man!. Bl#ndel and Hillha&e !hoQn that non*n#triti&e !Qeetener!Za!$artame in !ol#tionZQillenhance a$$etite and increa!e !hort*termfood intaYe. 2he re$ort4 7After inge!tion of a!$artame, the &ol#nteer!Qere left Qith a re!id#al h#nger com$aredQith Qhat the re$orted after gl#co!e. 2hi! re!id#al h#nger i! f#nctional,it lead! to increa!ed food con!#m$tion.7 2ardo[ and Friedman ha&e !hoQn that thi! #rge to eat more food afterarticial !Qeetener! can la!t #$ to ?>min#te! after the !Qeet drinY e&en Qhen all "lood te!t! !hoQ normal

&al#e!. 2he !hoQed that e&en Qhen "loodle&el! for in!#lin, the higher reading! of Qhich i! tho#ght to "e the ca#!eof h#nger, achie&ed normal le&el! te!tanimal! con!#med more food than the control "atch. Shat thi! mean! i!that the 7"rain7 retain! for a long time the#rge to eat Qhen the ta!te "#d! for !#gar are !tim#lated Qitho#t !#garha&ing entered the !!tem. 2he !Qeet ta!teQill ca#!e the "rain to $rogram the li&er to !tore !#$$lie! rather thanrelea!e !#$$lie! from it! !torage.Ba!icall, thi! $h!iological re!$on!e to !Qeetener! Qitho#t theiraccom$aning calorie! that the "od ha! "een told

ha! entered it Qill com$el the $er!on to nd and maYe good theregi!tered marYer for energ con!#m$tion. e!another $h!iological rea!on Qh $eo$le Qho con!#me diet !oda! tored#ce Qeight ma !#[er from the $arado%icalre!$on!e of their "od to re$eated !tim#lation of the ta!te "#d! Qith!#gar !#"!tit#te!.Shen ca[eine and a!$artame are introd#ced into the "od, the Qilldictate their !tim#lating e[ect on the cell$h!iolog in the "rain, the li&er, the Yidne!, the $ancrea!, theendocrine gland!, and !o on. A!$artame i!con&erted to $henlalanine and a!$artate. Both ha&e direct !tim#lator

e[ect! on the "rain. 2he !#m total of thee[ect of ca[eine and a!$artame Qill &er (#icYl e!ta"li!h a neQ modeof acti&it for the "rain j#!t "eca#!e the arere$eatedl a&aila"le in larger (#antitie! than the one! that Qo#ldotherQi!e e!ta"li!h a "alanced $h!iolog.Mo!t ne#rotran!mitter! are !econdar $rod#ct! from one or anotheramino acid. HoQe&er, a!$artate i! one of a $air

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of #ni(#e amino acid! that donTt need to "e con&erted to a !econdar$rod#ct to act on the "rain to ca#!e an e[ect.

 2here are recei&ing $oint! rece$tor!G for the!e tQo !tim#lant aminoacid! a!$artate and gl#tamateG on certainner&e cell! that in#ence "od $h!iolog &er dramaticall. 2he #!e of articial !Qeetener! for their fal!e !tim#lation of 7ner&eterminal!7 that regi!ter the entr of 7energ7!#$$lie! into the "od ha&e more !e&ere re$erc#!!ion! than !im$lca#!ing increa!e in Qeight. 2he!e chemical!con!tantl !Qing the "od $h!iolog in the direction dictated " thener&e !!tem the !tim#late. 2heir #!e Qitho#ta thoro#gh #nder!tanding of their long*term e[ect! in the "od, j#!t"eca#!e the al!o $lea!antl !tim#late the ta!te

"#d!, i! !hort!ighted. M #nder!tanding of the micro$h!iolog Qithincell! ca#!e! me concern Qhen I thinY of thero#tine #!e of the!e amino acid!. I Qorr for the o#tcome of the long*term e[ect of the direct !tim#lation of thener&e gland#lar !!tem! in the "rain Qith the!e chemical !Qeetener!. 2he are nat#rall $o!itioned for otherim$ortant, "#t "alanced f#nction!, in the "od.Re!earch ha! !hoQn that rece$tor! for a!$artate are a"#ndantl $re!enton !ome ner&e !!tem! Qho!e $rod#ct!al!o !tim#late the re$rod#cti&e organ! and "rea!t!. A con!tant!tim#lation of "rea!t gland! Qitho#t the other factor!

a!!ociated Qith $regnanc ma Qell "e im$licated in the ri!e in the rateof "rea!t cancer in Qomen. 2he hormone,$rolactin, ma $la a major role in thi! direction. 1ne of the le!!e%$lored com$lication! of a!$artame ma "e it!e[ect a! a $o!!i"le facilitator in cancer formation in the "rain. Fed torat!, a!$artame ha! "een im$licated in "raint#mor formation in e%$erimental animal!.A! an analog, imagine a !mall !ail "oat that i! going from one near"$ort to another and ha! to reach it!de!tination "efore darY Qhen the direction of the Qind! i! not ideal. If the !ailor, in!tead of $aing !trict attention to

the r#le! of !ailing, gi&e! in to the $lea!#re and e%hilaration of fa!t!ailing Qith the Qind, he Qill ha&e a"andoned hi!$#r$o!e and !ailed hi! "oat to totall di[erent and #nYnoQn !hore!, andin the darY. 2he odd! are that he and hi!"oat Qill not !#r&i&e the tri$.1n it! jo#rne of life, the h#man "od i! j#!t liYe a !ail "oat. If the minda"andon! $#r$o!e and forget! the de!ign of

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the "od, and gi&e! in to the o&er!tim#lation of the $alate Qith articialand non*re$re!entati&e $rod#ct! !#ch a!

!$ice!G, in the long r#n, the "od chemi!tr ma not "e a"le to deal Qithcon!tant fal!e information and not !#[erdao!.It i! $rimiti&e and !im$li!tic thinYing that one co#ld ea!il lace QaterQith all !ort! of $lea!#re*enhancing chemical!and !#"!tit#te the!e #id! for the nat#ral and dean Qater that theh#man "od need!. 0ome of the!e chemical!,ca[eine, a!$artame, !accharin and alcohol, thro#gh their con!tantlo$!ided e[ect on the "rain, #nidirectionallZ!ingle mindedlZ$rogram the "od chemi!tr Qith re!#lt! contrar tothe nat#ral de!ign of the "od. er m#ch liYe

the !ail "oat in the darY that Qill get "eached in #ncharted !hore! if it!!ailor gi&e! in to the $lea!#re! ande%hilaration of fa!t !ailing in $lace of !ticYing to the r#le! of !ailing Qith!afet in mind, the intaYe of Qrong #id! Qilla[ect the life of anone Qho contin#all con!#me! them.A! it ha! "een e%$lained !o far, the h#man "od ha! man di[erentindicator! Qhen it r#n! !hort of Qater. en e!to!time!, it need! onl Qater. A! it ha! "een e%$lained, it Qill com$licatematter! if one gi&e! the "od articial ta!te*enhancing #id! on a reg#lar "a!i! and in f#ll !#"!tit#tion of the Qaterneed! of the "od.

1ne !ho#ld remem"er that ca[eine i! !imilarl an addicti&e dr#g, the#!e of Qhich ha! "ecome 7legal.7 Children, in$artic#lar, "ecome &#lnera"le to the addicti&e $ro$ertie! of the!eca[eine*containing "e&erage!. 0tim#lating the"od at the earl !tage! of life of a child Qith $lea!#re*enhancingchemical! in "e&erage!, in !ome Qill $rogram the!en!e! to #!e harder addicti&e dr#g! Qhen the reach !chool age. 2h#!, the long*term and con!tant #!e of !oda! in general, and diet !oda!in $artic#lar, !ho#ld "e a!!#med to "ere!$on!i"le for !ome of the more !erio#! health $ro"lem! of o#r !ociet.Di!torting the $h!ical a$$earance of the

"od a! a re!#lt of e%ce!! fat !torage i! the r!t !te$ in thi! direction.0ome man#fact#red "e&erage! !ho#ld onl"e #!ed !$aringl, if at all, " o#nger $eo$le, Qhen the right $rogram!for the f#t#re health of a child i! the aim of$adre!.Dr. Marcia #tYoQ!Yi i! a n#trition con!#ltant. After reading m "ooY,!he con&inced her da#ghter Donna to "egin

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changing her ha"it in #id! intaYe. 2he re!#lt ha! a!to#nded the motherand da#ghter. 2he folloQing i! the

tran!cri$t of DonnaT! te!timonial.Dear Dr. BatmanghelidjA$ril ;9,5??= IM mother a!Yed, that I Qrite to o# and tell o# a"o#t m recent Qeightlo!! !#cce!!. I YnoQ that I co#ld ha&e am#ch more !#cce!!f#l lo!! if I Qo#ld folloQ o#r form#la and c#r" meating ha"it!, along Qith !tarting a reg#larro#tine of e%erci!e. HoQe&er j#!t getting m!elf to get o[ of @ to : can!of Mo#ntain DeQ a da i! a miracle in it!elf.Sithin the la!t ? month! to a ear, I ha&e !#cce!!f#ll "een a"le to Yee$89 e%ce!! $o#nd! of "aggage o[. e!to

a"le to Qear clothe! that I tho#ght Qo#ld ne&er to#ch m "od again. Ial!o ha&e j#!t a"o#t reached m goal !iefor m #$coming Qedding. E&en m anc' had to admit that lam looYingm#ch "etter than Qhen he r!t met me &ehace ao!.M !#cce!! ha! "een contri"#ted to faithf#ll drinYing 5; m "odQeight in o#nce! in Qater e&er da. Donde(#iera (#ego, !o doe! m Qater. 2o QorY, !ho$$ing, e&en m long < ho#r long carride!. 2hat doe! maYe for a lot of re!t area!to$!, "#t the are Qorth it.G I do treat m!elf to an occa!ional mineralQater or "eer Qhen I go o#t, "#t I ha&e

#!#all gotten m (#ota of Qater in for the da.1ne intere!ting thing that I ha&e noticed hoQe&er i! that once I ha&eni!hed drinYing m (#ota of Qater, I ha&ea"!ol#tel no de!ire to drinY anmore. Al!o I ha&e fo#nd that ITm notthir!t anmore and it Qill #!#all taYe meaQhile to drinY !ome other t$e of "e&erage Qhether it "e j#ice, milY,"eer, mineral Qater, etc.I am looYing forQard to 1cto"er 5!t Qhich i! m Qedding da Qhen I canQalY doQn the ai!le looYing "etter than Iha&e looYed in 59 ear!, !ince I grad#ated from high !chool. It Qill al!o"e nice to $#t m Qeight on m neQ dri&er!

licen!e Qitho#t ha&ing to cringe for the r!t time in m life. 2hanY! for the !maller me Donna M. #tYoQ!YiIt i! noQ Fe"r#ar of 5??9. Donna i! ha$$il married. B the time of herQedding in 1cto"er 5??=, !he had lo!t o&er=> $o#nd!. 2hi! !cience*"a!ed Qa of Qeight lo!! Qill "e $ermanent, Qherea! Qithonl food limitation, e&en if !ome Qeight i!

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lo!t, it i! regained in a !hort $eriod of time. Sor!e !till, one i! con!tantlho#nded " the fallac of needing to limit

thi! or that food, $artic#larl on the !#"ject of chole!terol content of food, a tem$orar $re!ent*da &og#e. Do not "econmocionado.Contrar to $re!ent trend! for e%cl#!ion of egg! fromdail diet, I eat a! man egg! a! I feel liYe eatingZno limitation Qhat!oe&er egg! ha&e a Qell*"alanced $rotein content. Ial!o ha$$en to #nder!tand hoQ e%ce!!chole!terol formation in the "od i! a!!ociated Qith $rolongeddehdration./ri!cilla /re!tonT! letter on the ne%t $age f#rther e%$lain! therelation!hi$ of dehdration, not onl to Qeight gain, "#tto the more de&a!tating $ro"lem of a!thma, the !#"ject of the ne%t

cha$ter. In taYing !te$! to $re&ent a!thma, !hemanaged to lo!e 89 $o#nd!. Another im$ortant $oint in her letter i! therole of !alt in di!ea!e $re&ention. 0alt i!im$ortant to the "od. 0alt !en!or! on the tong#e, Qhen !trongl!tim#lated, remo&e the "odT! an%iet and !to$ itfrom $anicYing for Qater. Shen !alt i! a&aila"le, the "od i! at lea!ta!!#red of an e\cient Qater ltration !!tem forit! emergenc !#$$l to the im$ortant cell!. Oo# Qill read more a"o#t!alt in cha$ter 5;./lea!e "ear in mind, the!e letter! are real*life !torie!. 2he are not7anecdote!.7 Se do not need !tati!tic! to

con&ince $eo$le of the e\cac of Qater, Qhen the "od i!demon!trating an #rgent need for it. Sho!e fa#lt i! it thatthe h#man "odT! regional call! for Qater, and it! $rogram! of ada$tation to dehdration, ha&e "een la"eled a!di!ea!e condition! I! there an $la#!i"le rea!on Qh, for e&al#ation of nat#ral treatment $roced#re!, Qe !ho#ldadhere to the !elf*!er&ing methodolog and the ard!ticY of the$harmace#tical ind#!tr 2heir inacc#ratea!!ertion! ha&e #ntil noQ ca#!ed !o m#ch $ain and agon for $eo$leQho!e "odie! Qere onl cring o#t for QaterA02HMA AND ALLERIE0

It i! e!timated that 5; million children !#[er from a!thma, and !e&eraltho#!and die e&er ear. Let #! declare anend to a!thma in le!! than &e ear!. Let #! !a&e children from thecon!tant fear of !#[ocation "eca#!e the do notrecognie the are thir!t for QaterA!thma and allergie! are indicator! that the "od ha! re!orted to anincrea!e in $rod#ction of the ne#rotran!mitter

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hi!tamine, the !en!or reg#lator of Qater meta"oli!m and it! di!tri"#tionin the "od.

It i! recognied that a!thmatic! ha&e an increa!e in hi!tamine content of their l#ng ti!!#e and that it i! the hi!taminethat reg#late! the "ronchial m#!cle contraction. 0ince one of the !ite!for Qater lo!! thro#gh e&a$oration i! in thel#ng!, "ronchial con!triction $rod#ced " hi!tamine mean! le!! Qatere&a$oration d#ring the act of "reathingZa!im$le nat#ral mane#&er to $re!er&e the "od Qater.Hi!tamine i! an agent that, a$art from it! Qater reg#lator role, ha!re!$on!i"ilitie! for anti"acterial, anti&iral, andanti*foreign agent! chemical! and $rotein!G defen!e !!tem! in the"od. At a normal le&el of Qater content of the

"od, the!e action! are held at an im$erce$ti&e or #ne%aggerated le&el.At a dehdrated !tate of the "od, to the$oint that the hi!tamine acti&it "ecome! e%aggerated for Qaterreg#lation, an imm#ne !!tem acti&ation ofhi!tamine*$rod#cing cell! Qill relea!e an e%aggerated amo#nt of thetran!mitter that i! held in !torage for it! otherf#ncione!.It ha! "een !hoQn in animal model! that hi!tamine $rod#ction inhi!tamine*generating cell! Qill decrea!e Qith anincrea!e in the dail Qater intaYe. Both of the!e condition! !ho#ld "ereg#lated Qith an alert and determined

increa!e in Qater intaYe. 1n a&erage, the!e condition! re!$ond after oneto fo#r QeeY! of Qater reg#lation of thec#er$o.Mr. /ecY, an a!thmatic !ince childhood, Qho al!o "ecame !en!iti&e to all!ort! of 7allergen!,7 i! no longer in fear ofthe!e health $ro"lem!. Mr. /at#ri! al!o te!tie! to the fact that hi! QifeT!allergic condition "ecame le!! $ro"lematic. Jo!e Ri&era, M.D., had for ear! !#[ered from allergie! and a!thma.HeQa! !e&erel allergic to cat!. De hecho,Qo#ld ne&er go to a ho#!e Qhere a cat Qa! al!o Ye$t. It !eem! he at onetime got &er !icY after "eing e%$o!ed to a

gato.A! a re!#lt of #!ing the neQ information a"o#t the relation!hi$ of dehdration to e%ce!! hi!tamine $rod#ction inthe "od, he ha! totall reco&ered from "oth of the!e condition!. 2o to$it all, he noQ treat! a!thmatic! Qith Qaterand !alt. Hi! letter i! on the ne%t $age./ri!cilla /re!tonT! letter o# ha&e alread !een. Joanie SineldT! letter i!al!o $rinted "eloQ. I onl di!c#!! the!e

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$er!on! "eca#!e their letter! te!tif to the fact that increa!ed dailQater intaYe ha! $ro&ided total relief from

a!thma and allergie! in groQn $er!on!, e&en after man ear! of !#[ering from the $ro"lem. Jo!e A. Ri&era M.D. Lect#rerMem"er Ad&i!or Board InternationalFederation of Holi!tic MedicineLi"ert 0(#are Medial Center9>5 North 5<th 0treet _ 0#ite U0GAllemom, /A 5:5>=@5>G<<@*<@8?5@?9Dr. F. Batmanghelidj lo"al Health 0ol#tion!Fall! Ch#rch, A. ;;>=8

Dear Dr. Batmanghelidj 2hi! letter i! in a$$reciation for the information that o# ha&e $re!entedconcerning Qater dehdration and a!thma.A! o# recall I ha&e had ad#lt on!et a!thma !ince I Qa! In college andha&e had man "o#t! of ana$hla%i! QhichQere life threatening.D#e to the information that o# ha&e $ro&ided I ha&e "een a"le toameliorate and c#re m oQn a!thma Qith Qaterand !alt intaYe. I ha&e "een a!thma free for a$$ro%imatel 5.9 ear! andha&e not had an reaction! to theallergen! of the $a!t.

 2he information ha! "een mo!t hel$f#l in maYing me aQare of Qhen andhoQ to drinY Qater and taYe !alt in order tohdrate m!elf and $re&ent an rec#rrence of a!thma.Al!o, I ha&e "een a"le to ad&i!e other $atient! Qith re!$irator andallergen $ro"lem! In hoQ to Increa!e their Qaterand !alt intaYe !afel, and to m amaement the amelioration ha! "eendramatic. 2hanY o# !ir for gi&ing me and other! the "reath of life thr# !omething!o !im$le a! Qater and !ailAtentamente, Jo!e A. Ri&era M.D.

 Joanie Sineld;>@ Se!t /ro!$ect A&en#e/itt!"#rgh, /A 59;>9 =5;G ?;;*5@;9 J#l 5:, 5??=Feredoon Batmanghelidj, M.D.;5=@ King! arden SaFall! Ch#rch A ;;>=8Dear Dr. Batmanghelidj4

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I am Qriting thi! letter to thanY o# for !haring o#r di!co&er a"o#t theneed for Qater Qith o#r reader!. tengo

"eneted greatl from folloQing o#r ad&ice on Qater intaYe. 2he change! in m health ha&e "een &er noticea"le.A!thma #!ed to "ea major health concern of mine. De!de (#eha&e "een drinYing eno#gh Qater, hoQe&er, I ha&e "een a"le to "reathne Qitho#t the #!e of an medicine. P#'di[erence thi! ha! made in m life. 2here ha&e "een other "enet! a!Qell, !#ch a! !ofter !Yin and increa!edmental aQarene!!.I am !o ha$$ to ha&e read o#r BooY, and I !hare o#r ad&ice Qith a!man $eo$le a! I can. 1nce again, thanYracia! $or !# a#da.

Atentamente, Joanie SineldDo not forget, if concentrated "lood reache! the l#ng!, local hi!tamine$rod#ction i! a nat#ral and a#tomatic$roce!o.It! e%aggerated relea!e Qill $romote "ronchial con!triction.If o# !#[er from a!thma or allergie!, increa!eo#r dail Qater intaYe. Do not o&er drinY thinYing o# can #ndo thedamage of man month! or ear! ofdehdration " e%ce!!i&e intaYe of Qater in a feQ da!. Oo# need todrinY a normal amo#nt e&er daZeight to ten:*o#nce gla!!e!Z#ntil f#ll hdration of the "od i! achie&ed o&er a

longer $eriod of time.Red#ce orange j#ice intaYe to one, or at mo!t tQo, gla!!e! a da. 2he$ota!!i#m content of orange j#ice i! high.High load! of $ota!!i#m in the "od can $romote more than #!#alhi!tamine $rod#ction. In a!thmatic!, thi! $ointde"e tener!e en c#enta.Mar B. i! one of the admini!trator! in a go&ernment de$artment that i!re!$on!i"le for the health care !!tem of amajor cit.0he !#[ered from a!thma for man ear!.0he no longerenjoed her QalY! in the $arY!. dic#ltad $ara"reath de$ri&ed her of the jo! of QalYing. It j#!t !o ha$$ened that one

of m colleag#e! at the Fo#ndation for the0im$le in Medicine "ecame aQare of her $ro"lem. Re!$onding to therecommendation to drinY Qater, !he indicated!he Qa! taYing am$le Qater. Shen !he Qa! a!Yed to dene her dailQater intaYe, it came to light !he Qa! drinYingman gla!!e! of orange j#ice and Qa! co#nting her j#ice intaYe a! QaterintaYe. It Qa! e%$lained to her that

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altho#gh orange j#ice contain! Qater, it cannot "e a!!#med it re$lace!the need! of the "od for $#re and !im$le

ag#a.0he acce$ted the ad&ice to c#t the j#ice intaYe and increa!e herQater intaYe.Sithin da! her !hortne!! of"reath im$ro&ed. 2he la!t time Qe heard from her, !he Qa! a$$arentlclear of her a!thma.Let me e%$lain another &er im$ortant i!!#e in a!thmaZthe role of !alt.Shen there i! Qater !hortage, the "od"egin! to retain !alt. In !ome $eo$le, the !alt reg#lator mechani!m! areine\cient. Add to thi! $h!iological$ro"lem "ad ed#cation a"o#t dieting and !alt*free diet! that ha&e"ecome e!ta"li!hed trend! in o#r !ociet. encertain $eo$le, !alt !hortage in the "od can occ#r and "ecome

!m$tom*$rod#cing in e%actl the !ame Qa a!Qater !hortage, !#ch a! !ome arthriti! $ain!. It i! m #nder!tanding thatin !e&ere a!thma attacY!, !alt !hortage i! amajor contri"#ting factor.I Qo#ld liYe to !hare an im$ortant !ecret Qitho#.0alt i! a nat#ral antihi!tamine. $er!ona!Qith allergie! !ho#ld "egin to increa!e their !alt intaYe to $re&ent e%ce!!hi!tamine $rod#ction.Sater i! needed in the l#ng! to Yee$ the air $a!!age! moi!t and $re&entthem from dring #$ Qhen air goe! in andcome! o#t. In dehdration, m#c#! !ecretion $rotect! air $a!!age! fromdring, m the r!t !tage! of a!thma, m#c#!

i! !ecreted to $rotect the ti!!#e!. 2here come! a time that m#ch m#c#!i! !ecreted and it !ta! $#t, $re&entingnormal $a!!age of air thro#gh the airQa!. 0odi#m i! a nat#ral m#c#!"reaYer, and it i! normall !ecreted to maYem#c#! 7di!$o!a"le.7 2hat i! Qh $hlegm i! !alt Qhen it come! incontact Qith the tong#e.0alt i! needed to "reaY #$ the m#c#! in the l#ng! and render it Qaterfor it! e%$#l!ion from the airQa!. endehdration, and in conj#nction Qith Qater $re!er&ation mechani!m!, a!im#ltaneo#! and a!!ociated !alt*$re!er&ation $rogram "ecome! e!ta"li!hed.Not lo!ing !alt to m#c#!

!ecretion "ecome! a $art of the $rogram. la"od need! to "e a!!#red that "oth Qater and !alt are a&aila"le "efore"ronchial con!triction rela%e! and m#c#!"ecome! loo!e eno#gh to "e !ecreted. In children Qith "roc!tic l#ng!,thi! relation!hi$ of !alt and Qater fornormal l#ng de&elo$ment and f#nction!, a! Qell a! m#c#! !ecretion,!ho#ld "e Ye$t in mind.

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 2hi! i! Qh Mr!. /re!tonT! and Dr. Ri&eraT! a!thma got "etter. 2hi! i! Qha!thma i! not a 7di!ea!e7 that get!

7c#red. 7It i! a $h!iological ada$tation of the "od to dehdration and!alt !hortage. It Qill rec#r antime !#\cientattention i! not $aid to reg#lar Qater and !alt intaYe. A $inch of !alt onthe tong#e after drinYing Qater fool! the "raininto thinYing a lot of !alt ha! arri&ed in the "od. It i! then that the "rain"egin! to rela% the "ronchiole!. Alcohol andca[eine contri"#te to !e&ere a!thma attacY!. /eo$le Qith a!thma !ho#ld!lightl increa!e their !alt intaYe.LIFE02OLE MEDICAL CEN2ERDr. Batmanghelidj;5=@ King! arden Sa

Fall! Ch#rch, A ;;>=8Dear Dr. Batmanghelidj4Ma ;=,5??9Reference4 Jeram Chri!to$herI am Qriting to thanY o# for o#r Yind a!!i!tance in treating Jerem T!allergie!. A! o# YnoQ, Jerem i! m eightear*old !on Qho !#[ered for the la!t 8*= ear! Qith !e&ere allerg!m$tom! related to allergic rhiniti! and a!thma.More Recentl he ha! had !ignicant cora and co#ghing Qhich i!a!!ociated Qith hi! a!thma. 1n a"o#t the ;:thof A$ril 5??9, Qe "egan a $rogram of rehdration in&ol&ing hi! drinYing

tQo c#$! of Qater "efore food or e%erci!eand e%cl#ding all other #id!. In addition, he con!#me! a half tea!$oonof !alt Qhich i! added to hi! food to o[!etthe increa!ed Qater intaYe.Sithin 8*= da! he !hoQed dramatic im$ro&ement he no longer had!e&ere and e%ce!!i&e m#c#! $rod#ction, hi!co#ghing had &irt#all !to$$ed, and hi! !neeing and other allerg!m$tom! Qere totall gone. 2herefore Qedi!contin#ed hi! Benadrl and Al"#terol and contin#ed hi! hdration$rogram. Jerem ha! "een folloQing thi! $rogram noQ for a$$ro%imatel fo#r and

a half QeeY!, !$ending almo!t fo#r QeeY!o[ hi! medication and i! doing (#ite Qell. Not onl ha&e hi! !m$tom!cleared !#"jecti&el, "#t in term! of o"jecti&ending!, hi! $eaY oQ &ol#me! ha&e "een Qithin normal range. Hi!con!tant medication*ind#ced droQ!ine!! ha!di!a$$eared and a! a re!#lt he i! more alert, and hi! !chool grade! ha&eim$ro&ed.

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 2herefore I Qant to em$ha!ie hoQ e[ecti&e thi! treatment ha! "een for Jerem and I Qi!h o# Qell in !haring thi!

co!t e[ecti&e and &er e\cacio#! $rogram Qith other!.1nce again Dr. Batmanghelidj, I thanY o# for ad&i!ing me on the neQtreatment $rogram of JeremT! allergie! andel a!ma.er tr#l o#r!.Cherl BroQn*Chri!to$her, M.D.5=5? Fore!t Dri&e _ 0#ite ;>; . Anna$oli! _ Marland ;5=>8 =5>G;@:*9>>9A! o# read in Dr. Chri!to$herT! letter to me, her !on Qa! on tQodi[erent medication! for hi! a!thma. El aireca$acit of hi! l#ng!, e&en Qith medication!, Qa! @> $ercent of normal.

In one month of Qater and !alt treatment,hi! l#ng ca$acit Qent to 5;> $ercent of normal, Qith no medication.Aaron Sarner i! 5> ear! old and Qa! $#t on &e di[erent medication!to treat hi! a!thma. In hi! motherT! Qord! tome4 72he !ched#le m !on Qo#ld need to Yee$ to maintain hi!medication! i! not &er reali!tic for a 5>*ear*old,and after tQo da! on medication! he Qa! feeling Qor!e and hi! headh#rt, throat h#rt, mo#th h#rt and he Qa! tired,droQ!, gro#ch and "ecame !#n*!en!iti&e.7 Jerem and Aaron are noQo[ medication!, and their $arent! aree#fórico.2he information that Qater and !alt c#re a!thma Qa! aired on

 J#ne 9,5??9, " /a#l Har&e NeQ! for the r!ttiem$o. 2hi! good neQ! i! noQ "ecoming YnoQn more and more. Se ma "ea"le to end in le!! than &e ear! the !co#rgeof medical ignorance a"o#t chronic dehdration that $ermit! !o manmillion! of innocent children to !#[er#nnece!!aril to the $oint of a feQ tho#!and of them ding of a!thma.Shat the!e children need to realie i! the factthat for them, "reathing ha! "ecome di\c#lt "eca#!e the are !o thir!t.M#lti$l the im$act of increa!ed Qater intaYe in the $re&ention and c#reof a!thma attacY!, a! !een in JeremT! and

AaronT! ca!e, to the other 5; million a!thmatic children, and o# can!#ddenl !ee the $o!!i"ilit of !a&ing them allfrom 7!#[ocation and death from dehdration,71nl Qith o#r acti&e hel$, and if Qe can get the media to lend a hand ined#cating the $#"lic a"o#t the role of Qaterin $re&ention of a!thma, can Qe !a&e the!e innocent children Qho areca#ght in the gri$! of ignorance andcommerciali!m in medicine.

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01ME ME2AB1LIC A0/EC20 1F 02RE00 AND DEHODRA2I1N7I rml "elie&e that if the entire materia medico a! noQ #!ed co#ld "e

!#nY to the "ottom of the !ea, it Qo#ld "e allthe "etter for manYindZand all the *Qor!e for the !he!.7 1li&er SendellHolme!IN0ULIN*INDE/ENDEN2 DIABE2E0Ba!icall, there are tQo t$e! of dia"ete!. For the treatment of one,in!#lin i! needed "eca#!e the $ancrea! nolonger man#fact#re! in!#lin. 2hi! t$e i! called in!#lin*de$endentdia"ete!. For the treatment of the other, !omechemical! are needed that can grad#all relea!e in!#lin from the$ancrea! !o the dia"etic can control the clinical!+ntoma!.2hi! t$e i! called in!#lin*inde$endent dia"ete!the $ancrea!

!till ha! the a"ilit to man#fact#re in!#lin.In!#lin*inde$endent dia"ete!, e!ta"li!hed in the elderl and Qhich can"e reg#lated " the intaYe of 7ta"let7 form! ofmedication, i! mo!t $ro"a"l the end re!#lt of "rain Qater*decienc, tothe $oint that it! ne#rotran!mitter !!tem!Z$artic#larl the !erotonergic !!temZi! "eing a[ected. 2he $h!iologof the "rain i! de!igned in !#ch a Qa that ita#tomaticall "egin! to $eg*#$ the gl#co!e thre!hold !o that it canmaintain it! oQn &ol#me and it! oQn energre(#i!ito!.2he "rain need! gl#co!e for it! energ &al#e and it! meta"oliccon&er!ion to Qater.2he $re&alent

con!en!#! of o$inion i! that the "#lY of energ re(#irement in the "raini! $ro&ided " !#gar alone. Mi $er!onal&ieQ i! that thi! i! onl the ca!e if there i! Qater and !alt !hortage in the"od. Sater and !alt are a"!ol#tele!!ential for the generation of hdroelectric energ, $artic#larl forne#rotran!mi!!ion mechani!m!. 2he rea!on and the mechani!m for altering "lood !#gar le&el! i! (#ite!im$le. Shen hi!tamine "ecome! acti&e inQater reg#lation and energ management, it al!o acti&ate! a gro#$ of !#"!tance! YnoQn a! $ro!taglandin! /C!G./C! are in&ol&ed in a !#"ordinate !!tem for rationed di!tri"#tion of 

Qater to the cell! in the "od. 2he $ancrea!Za &er com$le% gland located "etQeen the !tomach andthe d#oden#mZother than "eing the !eatof in!#lin man#fact#re i! engaged in the $rod#ction of co$io#! (#antitie!of a "icar"onate*containing Qater!ol#ción.2hi! "icar"onate !ol#tion i! em$tied into the d#oden#m tone#tralie acid coming from the !tomach. e!te

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i! hoQ the acid from the !tomach i! ne#tralied. It ha$$en! that Qhilethe !tim#lating agent, / of the E t$e, ma

"e in&ol&ed in !h#nting circ#lation to the $ancrea! !o that the Qater"icar"onate !ol#tion can "e made, at the !ametime it nat#rall inhi"it! the !ecretion of in!#lin from the $ancrea!. Itact! liYe a &er tightl o$erated !er&o*mecani!mo.2he more one !!tem ha! to "e !er&ed, the more the other!!tem Qill "e decommi!!ioned.6/or (#'0im$l, in!#lin $romote! mo&ement of $ota!!i#m and !#garinto the cell! of the "od.It al!o $romote! entrof !ome amino acid! into cell!. Accom$aning the $a!!age of !#gar,$ota!!i#m, and amino acid!, Qater Qill al!o$a!! into the cell that ha! "een !tim#lated " in!#lin. 0#ch action Qill

a#tomaticall red#ce the a&aila"le Qater thati! more ea!il acce!!i"le from o#t!ide the cell!. In a dehdrated !tate,the action of in!#lin Qo#ld "econtra$rod#cente.2he logic em$loed in the de!ign of the "od ha!therefore in!talled the tQo action! of Qaterdi!tri"#tion to the $ancrea! and the needed inhi"ition of in!#lin action inthe !ame agentZ$ro!taglandin E. In thi!Qa, and at the e%$en!e of !e&ere de$ri&ation of !ome cell!, Qater i!made a&aila"le for the act of food dige!tionand acid ne#traliation in the inte!tine!.A! it ha$$en!, Qhen in!#lin !ecretion i! inhi"ited, e%ce$t for the "rain,

the meta"oli!m of the "od i! !e&ereldi!r#$ted. In a dehdrated !tate, the "rain "enet! from in!#lininhi"ition. 2he "rain cell it!elf i! not de$endent onin!#lin for it! f#nction! Shile cell! in mo!t other $art! of the "od aretotall de$endent on the $ro$ertie! of in!#linfor their normal f#nction. If Qe thinY a"o#t it, there i! a nat#ral logic tothe #ltimate $rod#ction of in!#lin*inde$endentdia"ete! in !e&ere chronic dehdration. Sh i! it called in!#lin*inde$endent dia"ete! Beca#!e the "od can !tillman#fact#re in!#lin, altho#gh it taYe! the in#ence of !ome chemicalagent! to $romote it! !ecretion.

 2hi! $henomenon of in!#lin inhi"ition Qith dehdration !hoQ! that the$rimar f#nction of the $ancreatic gland i!directed at the $ro&i!ion of Qater for food dige!tion. In!#lin inhi"ition i!an ada$tation $roce!! of the gland to thedehdration of the "od. 2RO/21/HAN AND DIABE2E0E&en the !im$le!t e%$lanation on tr$to$han ma !eem toocom$licated. HoQe&er, !ome &er "a!ic #nder!tanding

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a"o#t thi! amino acid m#!t "e $ro&ided to maYe !en!e of !ome of the!tatement! that are $re!ented in thi! "ooY

Remem"er, the "od i! a &er com$le% chemical $lant that i! e%tremel!en!iti&e to #ct#ation! in the oQ of it!$rimar raQ material!. 2he "rain i! de!igned to re!#!citate it!elf, Qhen there i! Qater and !alt!hortage in the "od. It rai!e! the le&el! of!#gar in circ#lation. 2he rai!ed le&el of !#gar i! !#$$o!ed to "alance the&ital o!motic e(#ili"ri#m, in the !ame Qathat a doctor re!#!citate! a $atient " the #!e of !#gar and !alt*containing intra&eno#! #id dri$!. 1ne al!o need!to recognie another !im$le $oint4 1!motic force! that m#!t "e a&aila"lefor e%tracell#lar #id &ol#me reg#lation are

de&elo$ed $rimaril " it! !alt content, " it! rai!ed !#gar content, and!ometime! " it! increa!ed #ric acid content.B#t in in!#lin*de$endent t$e of dia"ete!, there ma "e !e&ere !alt!hortage, in Qhich ca!e the "rain ha! noalternati&e "#t to rai!e the le&el of !#gar e&en more to com$en!ate forthe loQ !alt re!er&e! in the "od. e!te$roce!! i! an a#tomatic !te$ in the de!ign of the "rain acti&it that i!ma!ter*managed " the &ario#! direct, andindirect, f#nction! of tr$to$han. It ha! al!o "een !hoQn that tr$to$hani! the "a!ic !#"!tance that the "od need!a! a &ital ingredient to con&ert into the three or e&en fo#r mo!t e!!ential

ne#rotran!mitter! !o far recognied.In in!#lin*inde$endent dia"ete!, one need! to $a $artic#lar attention toade(#ate $rotein intaYe to maYe #$ for the$o!!i"le tr$to$han in!#\cienc that ma "e the root ca#!e of thedi!ea!e. 6/or (#'It !eem! that dehdration ca#!e!a !e&ere de$letion of "rain tr$to$han, a mo!t e!!ential amino acid inthe h#man "od. Shen there i! ade(#ateamo#nt of tr$to$han in the "rain, among it! other e[ect!, the $ainthre!hold i! rai!edZone end#re! $ain "etter.2r$to$han content in the "rain !hoQ! a great dro$ in it! le&el! in !omedia"etic animal!.

 2o !tre!! thi! $oint again, !alt, !#gar, and #ric acid are in&ol&ed in"alancing the o!motic force! of #id com$o!itionheld o#t!ide the cell!. 0alt content i! re!$on!i"le for the greate!tcontri"#tion to the e%tracell#lar o!motic "alance.Reg#lator $ro$ertie! of tr$to$han it!elf, or it! de$endentne#rotran!mi!!ion !!tem!, o$erate a mea!#ringmechani!m for the amo#nt of !alt that i! Ye$t in the "od. 0erotonin,tr$tamine, melatonin, and indolamine are

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deri&ed from tr$to$han, and all are ne#rotran!mitter!. 2h#!, tr$to$hani! the nat#ral "rain reg#lator for !alt

a"!or$tion in the "od. It !eem! that loQer le&el! of tr$to$hanZand incon!e(#ence, it! ne#rotran!mitter $rod#ct!ZQill e!ta"li!h loQer*than*normal !alt re!er&e!.A! a "acY*#$ mechani!m in the "od, the RA !!tem !eem! tocom$en!ate " ind#cing !alt retention in the "od.Hi!tamine and it! RA !!tem acti&it "ecome increa!ingl engaged if thetr$to$han*de$endent ne#rotran!mitter!!tem! "ecome le!! in&ol&edZthro#gh !hortage or increa!ed"reaYdoQn of tr$to$han. It folloQ! that a loQ*!altdiet i! not cond#ci&e to the correction of a dia"eticT! high "lood !#gar._ If the "lood !#gar i! to come doQn, a !light #$Qard adj#!tment of dail

!alt intaYe ma "ecome #na&oida"le. 2r$to$han i! al!o a mo!t $rominent amino acid em$loed in thecorrection of error! in the $roce!! of DNA7$rinto#t7 or re$lica $rod#ction. Sith another amino acid, l!ine, theform a "ridging !!tem l!ine*tr$to$han*l!ine tri$odG that c#t! and !$lice! the inacc#racie! in DNA tran!cri$tion. 2hi! $ro$ert of tr$to$han i! mo!te!!ential to $re&ention of cancer cell de&elo$ment in the "od.Sith the "rainT! tr$to$han re$leni!hment, the hi!tamine*o$erated!!tem! Qill "e trimmed doQn to their $rimarre!$on!i"ilitie!Z#ne%aggerated f#nction!. 0alt content of the "od Qill

"e "etter reg#lated. 2he !en!ation le&el"efore regi!tering $ain !tim#l#! Qill "e rai!ed.Acid !ecretion in the!tomach Qill come #nder normal control. !angre$re!!#re Qill "e normalied to it! nat#ral le&el! for the o$eration of allf#nction! in the "od4 Yidne!, "rain, li&er,l#ng!, ga!trointe!tinal dige!ti&e acti&itie!, 7!hoQer*head7 ltration of Qater into the ner&e cell!, the joint!, and !o onQill f#nction Qithin their normal range of acti&it. 2here i! a direct relation!hi$ "etQeen QalYing and the "#ild*#$ of the"rain tr$to$han re!er&e!. Ha &ario!amino acid! that com$ete for cro!!ing the nat#rall de!igned "arrier

!!tem into the "rain. 2he all ha&e to7$igg"acY7 on the !ame tran!$orter $rotein!. 2he!e com$etitor! totr$to$han are gro#$ed #nder the title of"ranched*chain amino acid! BC amino acid!G. D#ring e%erci!e, the!e BCamino acid!, along Qith the fat!, are #!eda! f#el in the larger m#!cle!.M#!cle! "egin to $icY #$ the!e amino acid!from the circ#lating "lood. Como re!#ltado, la

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odd! are changed in fa&or of tr$to$han for it! $a!!age acro!! the"lood*"rain*"arrier and into the "rain. 1ne major

$h!iological &al#e to e%erci!ing i! the direct relation!hi$ of m#!cleacti&it to the "#ild*#$ of the "rain tr$to$hanre!er&e!._ 2he "rain tr$to$han content, and it! &ario#! "*$rod#ctne#rotran!mitter !!tem!, are re!$on!i"le formaintenance of the 7homeo!tatic "alance of the "od.7 Normal le&el! of tr$to$han in the "rain maintain a Qell*reg#lated "alance in all f#nction! of the "odZQhat i! meant "homeo!ta!i!. Sith a decrea!e in tr$to$han !#$$lto the "rain, there i! a $ro$ortionate decrea!e in the e\cienc of allf#nction! in the "od.

De$re!!ion and !ome mental di!order! are the con!e(#ence of "raintr$to$han im"alance. /roac #!ed in !omemental di!order!, $artic#larl in de$re!!ion, i! a dr#g that !to$! theenme! that "reaY doQn !erotonin, a"$rod#ct of tr$to$han. Shen more !erotonin i! $re!ent, all ner&e!f#nction normall. HoQe&er, /roac cannotre$lace the indi!$en!a"le role of tr$to$han it!elf. 1ne ha! to QorY atre$leni!hing "od re!er&e! of tr$to$hanthro#gh a "alanced diet and reg#lar Qater intaYe.M re!earch ha! !hoQn there i! a direct relation!hi$ "etQeen QaterintaYeZhemodil#tionZand e\cienc of

f#nction in the tran!$ort !!tem for the $a!!age of tr$to$han into the"rain. Sater !hortage and $ro$ortionatehi!tamine relea!e "ring a"o#t an increa!e in the rate of tr$to$han"reaYdoQn in the li&er. It !eem! that ade(#ateQater intaYe arre!t! the increa!ed and ine\cient meta"oli!m of tr$to$han in the "od. Chronic dehdration ca#!e!it! lo!! from the $ool of di[erent amino acid! held in the"od.2r$to$han cannot "e man#fact#red in the "od lom#!t "e im$orted thro#gh food intaYe. It i! one of the e!!ential aminoacid!. 2h#!, hdration of the "od, e%erci!eand the intaYe of right food! hel$ re$leni!h "rain tr$to$han re!er&e!.

Another mo!t im$ortant fact to remem"er i! the idio!ncra!ie! that!eem to o$erate in $rotein meta"oli!m and theirfa"ricar./rotein! are man#fact#red from joining amino acid!together.2here are ;> amino acid! AA!G fromQhich di[erent $rotein! are made. Each $rotein ha! a di[erent mi% of the!e AA!. De$ending on the !e(#ence of themi%, di[erent characteri!tic! are in!talled in each $rotein. De$ending onthe !e(#ence and the n#m"er, the mi% can

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f#nction a! enme!, a! a!!em"l line! for the man#fact#re of other$rotein!, and a! energ generator! in the

hdroelectric $#m$ #nit!.All f#nction! of the "od are reg#lated " the !$ecial $ro$ertie! and the7!e(#ence characteri!tic!7 of it! AA! #!edin enme! and "od $rotein!.2here are eight e!!ential AA! that are notman#fact#red in the h#man "od ello!m#!t "e im$orted from food intaYe.2here are three AA! that can "eman#fact#red "#t in limited (#antitie!. encertain time!, the al!o "ecome $artiall !carce.2he other nine AA! aream$l man#fact#red Qithin the "od. 0i elnormal $ercentage! held in the re!er&e $ool of AA! in the "od "egin! to#ct#ate "eond a certain range, !ome

AA! are d#m$ed di[erentl "roYen or con!#medG to Yee$ thecom$o!ition of the AA $ool Qithin the normal rangefor f#t#re $rotein and enme man#fact#re. 1f the AA! that get d#m$edin !tre!!, tr$to$han !eem! to "e one ofthe mo!t im$ortant.HoQe&er, one can not con!#me thi! or that amino acid " it!elf to"alance the $ool, e&en if one YneQ all the intricateramication!. 1ne m#!t con!#me the f#ll range of AA! to "#ild the7re!er&e $ool7 in d#e time. 2he $reca#tion onecan taYe i! to eat $rotein! that ha&e the!e AA! in am$le $ro$ortion!.0ome $rotein!, !#ch a! long*e%$o!ed meat,

ma "ecome decient in !ome amino acid!. 2he "e!t $rotein! are tho!e!tored in the germinating !eed! of $lant!,!#ch a! lentil!, grain!, "ean!, etc.Zal!o in egg! and milY that nat#re$ro&ide! to $rod#ce the ne%t generation ofchicYen! and to feed the calf.Lentil! and green "ean! in $artic#lar are good !tore! for AA! in foodingredient!. 2he contain a"o#t ;: $ercent$rotein!, <; $ercent com$le% car"ohdrate!, and no oil. 2he!e t$e! of food! are " nat#re "etter !tore! for$ro&i!ion of AA! in $ro$ortioned amo#nt!. After all, the!e "etter choiceof 7food!7 are nat#rall de!igned to

$rocreate a 7$erfect7 re$lica of the !$ecie! concerned. 2he !torage of a"alanced amino acid com$o!ition a! a life!tarter i! $art of the $roce!!.In!#lin*inde$endent dia"ete! !ho#ld "e treated Qith an increa!e in QaterintaYe, e%erci!e, and diet mani$#lation to$ro&ide the nece!!ar amino acid "alance for ti!!#e re$air, incl#ding"rain ti!!#e re(#irement!. 0alt reg#lation

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!ho#ld al!o "e Ye$t in mind. Dia"ete! i! a good e%am$le of the ne%t*generation damage that i! ca#!ed "

la de!hidratación.Sherea! the on!et of dehdration*ind#ced dia"ete! i!normall !een in the elderl and it i! oftenre&er!i"le, the more !erio#! and !tr#ct#rall damaging &ariet of thedi!ea!e i! often inherited " the o[!$ring. J#&enile dia"ete! Qill need the !ame a$$roach to it! earl $re&enti&etreatment "efore $ermanent !tr#ct#raldamage can taYe $lace. It !ho#ld "e remem"ered that the genetictran!cri$tion mechani!m of the $arent!Zin$artic#lar the motherZif a[ected " amino acid $ool im"alance, Qill "ee(#all re$re!ented in the o[!$ring. ene[ect, thi! i! hoQ genetic damage and inherited di!order! e!ta"li!h.

Shat o# Qill read in the ne%t feQ $aragra$h!i! de!igned to !hoQ a re$re!entati&e $roce!!.IN0ULIN*DE/ENDEN2 DIABE2E0In in!#lin*de$endent dia"ete!, the a"ilit to $rod#ce in!#lin "$ancreatic cell! i! lo!t. 2o control dia"ete!, act#alinjection! of in!#lin on a reg#lar dail "a!i! are e!!ential. 2hi! conditioni! "ecoming !lightl "etter #nder!tood.Sithin the $roce!! of $rotein "reaYdoQn to mo"ilie the amino acidre!er&e!, corti!one*relea!ing mechani!m! al!o$romote the !ecretion of a !#"!tance called IL*5 interle#YinG. 2here i! amagnifing e[ect "etQeen corti!one

relea!e mechani!m! and IL*5 $rod#ction each $romote! the !ecretion of the other. IL*5 al!o $romote! the!ecretion of another !#"ordinate !#"!tance called IL*@. 2h#!, contin#edIL*5 $rod#ction Qill dri&e a !im#ltaneo#!$romotion of IL*@ $rod#ction.It ha! "een !hoQn in cell c#lt#re! that IL*@ de!tro! the DNA !tr#ct#re of in!#lin*$rod#cing cell!. 2he!e IL*@ treatedcell! can not $rod#ce an more in!#lin. I a!!#me and ha&e $#"li!hedthi! &ieQG that contin#ed dehdration and it!#nchecYed di!t#r"ance of the amino acid meta"oli!m in the "od i!mo!t $ro"a"l re!$on!i"le for the de!tr#ction of

DNA !tr#ct#re in the $ancrea!Tin!#lin*$rod#cing "eta cell!. 2h#!, dehdration and it! $romotion of !tre!! $h!iolog ma #ltimatel al!o "ere!$on!i"le for the emergence of in!#lin*de$endent dia"ete!._Hence, the $aradigm !hift can !cienticall e%$lain the role of Qater indi!ea!e $re&ention andor their c#re. con!trict and a"!ol#tel reg#lar dail Qater intaYe to $re&ent the !tre!!e!and a!!ociated damage! of dehdration, the

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chief cond#ctor and !#$er&i!or of the "odT! Qell*"eingZtr$to$han andit! ne#rotran!mitter deri&ati&e!, !erotonin,

tr$tamine and melatoninZQill "e Qell*$o!itioned to reg#late allf#nction!. A "alanced amino acid intaYe in !im$le$rotein! Qill maYe !#re eno#gh of all of them i! made a&aila"le to the"od. Reg#lar dail QalY! Qill Yee$ m#!cle!Qell*coordinated and correct an $h!iological $roce!!e! that aree!ta"li!hed in the "od a! a re!#lt of an%iet andemotional 7!tre!!.7_2he a"o&e three m#!t! are the mo!t &ital and "a!ic anti*aging$reca#tion!. 2he are e!!ential !te$! to &er goodhealth and a Qell hdrated and health !Yin that need! Qater tocon!tantl re$lace that Qhich it lo!e! to the o#t!ide

medio am"iente.2hat i! Qhen "lood &e!!el! to the face and the "od Qillo$en #$ and $ro&ide nece!!ar no#ri!hmentfor e%$o!ed !Yin cell!.Shen the "od i! Qell hdrated, all of the $h!iological and hormonal$rere(#i!ite! to a !ati!fing !e% life and more*than*ade(#ate li"ido Qill "e in $lace. In addition, one or tQo gla!!e! of Qater "efore 7the e&ent7 Qill hel$ in achie&inga rmer and !#!tained erection in men and the jo! of $artici$ation inQomen.NES IDEA0 1N AID0In thi! !ection, I am !haring Qith o# the re!#lt of man ear! of m oQn

re!earch into the $h!iological rea!on! andrelation!hi$! of A(#ired Imm#ne Decienc 0ndrome ADD0G tometa"oli!m di!t#r"ance that can "e ca#!ed "!e&ere emotional and $h!ical !tre!!. I hold the idea that AID0 i! not a&iral di!ea!e "#t a meta"olic di!order$reci$itated " an e%aggerated Qa of life. It can e(#all "e ca#!ed "!e&ere maln#trition in $oorer and famine*!tricYen !ocietie!. I YnoQ thi! &ieQ i! com$letel again!t c#rrent "elief!forced " media $re!entation of a !ocial$ro"lem, "#t it i! the re!$on!i"ilit of dedicated !cienti!t! to taYe intocon!ideration and e%$lore all a!$ect! of thi!

$ro"lema.Se are onl noQ "eginning to #nder!tand Qhat AID0 ma"e.Se YnoQ one thing it i! not4 a &ir#!*$rod#ced di!ea!eAt the end of thi! !ection, o# Qill "e introd#ced to#nfolding e&ent! aro#nd AID0 re!earch. lo har'al!o !hoQ o# that I ha&e "een one of the leader! of the contro&er!.At thi! $oint, and thro#gh the $er!$ecti&e of a !tre!!*ind#ced meta"olic!!tem di!t#r"ance, a more acc#rate

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#nder!tanding of AID0 ma al!o "ecome $o!!i"le. Se !ho#ld not clo!eo#r ee! to neQ information j#!t "eca#!e

Qe are !old on the idea that thi! condition i! ca#!ed " a cla!! of &ir#!e!con&enientl called H#man Imm#neDecienc ir#! HIG.For !ome time noQ, it ha! "een !cienticall !hoQn and recognied thattho!e !#[ering from AID0 demon!trate amarYed &ariation from the normal 7amino acid $ool com$o!ition7Zthein&entor of amino acid! a&aila"le in theirc#er$o.2he are con!i!tentl and dra!ticall !hort of methionine, c!tineand c!teineZ&er im$ortant amino acid!. 2he al!o ha&e a manifold ri!e in le&el! of arginine and gl#tamate. 2hi!!tate of a &er dra!tic amino acid im"alance

!eem! to la!t for !ome time "efore the $atient "ecome! &er !icY It!eem! in clinicall o"&io#! and recognia"leAID0*!#[ering $eo$le, thi! $attern for amino acid com$o!ition of the"od i! dominant. In the !ection on tr$to$han,it Qa! e%$lained that the amino acid $ool com$o!ition of the "od canchange and "ecome de$leted if !ome of themare #!ed #$ more than other!.In a !erie! of other e%$eriment!, Qhen IL*@ and another !imilar!#"!tance 2NF *t#mor necro!i! factorG are addedto a cell c#lt#re medi#m that contain! cell! Qith the a"ilit to $rod#cethe &ir#!, $article! la"eled HI are e%tr#ded. 0i,

"efore the addition of IL*@ or 2NF, c!teine i! added to the !ame c#lt#remedi#m, HI $article! are not $rod#ced. 2h#!, there i! a direct correlation "etQeen HI $rod#ction in AID0 andamino acid content of the &ir#!*groQing cell.It !eem! on the face of it that AID0 $atient! are &ictim! of an im"alancein their "odie!T amino acid com$o!ition. !ithe co#ld correct their $rotein meta"oli!m, the might "e a"le to!#r&i&e, and their "odie! might "e a"le to $rod#ce!#\cient re!i!tance to ght other ac#te infection!. After all, e&en for theman#fact#re of anti"odie! to defendagain!t other "acteria, the "od need! the "a!ic amino acid ingredient!

in their correct $ro$ortion!.It i! #nfort#nate that Qe are looYing at the &ir#! and not !eeing the$h!iological im"alance in AID0 $atient!. e!al!o #nfort#nate that Qe do not #nder!tand the !#"ordinate meta"olicrole! of IL*@ to the corti!one*relea!ingmechani!m and IL*5 $rod#ction. 2he!e agent!, and other! in their $acY,are $rod#ced to mo"ilie $rimar raQ

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material! from "od re!er&e! to ght !tre!! and re$air $o!!i"le damage!ca#!ed " ha&ing confronted an

$artic#lar !tre!!or. 2heir f#nction i! de!igned aro#nd the mechani!m of "reaYing doQn $rotein! held in the m#!cle!of the "od and con&erting them to their "a!ic amino acid! for their #!ein the li&er. 0o, the general direction in!e&ere !tre!!*damage i! to mo"ilie the e!!ential ingredient! for theiremergenc re*#!eZa $roce!! of feeding o[the "od it!elf.A "r#i!ed "o%er or a $er!on tra#matied in an accident or after re$eated!#rger Qill de$end on the!e $h!iological$roce!!e! to clear the ine[ecti&e and non&ia"le ti!!#e and re$air andremodel the !ite of damage. 0i el

recon!tr#ction i! e%ten!i&e and IL*@ and it! com$anion 2NF are in&ol&ed,"reaYdoQn of DNA or RNA of thedamaged and ding cell! Qill $rod#ce e%act fragment! to dear thede"ri!, &er m#ch liYe ha&ing to di!mem"er the!teel !tr#ct#re of a large "#ilding that can not "e 7"#lldoed aQa7 andha! to "e carried o[ the !ite, a $iece at atiem$o.2hi! i! a &er Qell recognied $roce!! in the re!earch of !#rgicalQo#nd!.It i! mo!t #nfort#nate that &irologi!t! are $re!enting the 7!ite clearingaction7 of the!e tQo agent! in the "od a!!te$! in the $rod#ction of HI in cell c#lt#re media. 1n thi! fragment of 

#nconnected information i! $laced the Qholearg#ment that AID0 i! a &ir#!*ca#!ed di!ea!e. 6/or (#'Beca#!e a te!tha! "een de!igned that marY! and !hoQ! the$artic#lar fragment! $rod#ced " IL*@ or 2NF. It !eem! that !ome of the!e DNA or RNA $article! are la"eled a!H2*and that i! Qh there are !e&eral t$e!. It i! more #nfort#nate thatthe amino acid com$o!ition of H2 it!elf&er m#ch re!em"le! that of &a!o$re!!in. A &accine that Qo#ld arre!tHI acti&it Qillmo!t $ro"a"l arre!t theacti&it of &a!o$re!!in. 2hi! !eem! to "e the rea!on a QorYa"le &accineagain!t HI ha! not et "een $rod#ced.

Unfort#nate to the e%treme i! the 7commercialiation of the idea7 thate&erone Qho !hoQ! a $o!iti&e HI te!t Qill!oon die from AID0, "eca#!e the an%iet of ha&ing an inc#ra"le di!ea!eco#ld "ecome a Yiller " it!elf.Sitho#t getting into the emotional !ide of thi! i!!#e, and !ticYing !trictlto a !cientic #nder!tanding of the h#man"od, Qe ha&e to "ecome aQare of a !im$le fact. 2i!!#e! of the &aginaand the an#! and rect#m are de!igned for

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di[erent $#r$o!e!. It i! tr#e "oth ha&e !imilar !en!or !!tem! attachedto a !ingle central mechani!m for the

regi!tration of $ain and $lea!#re, "#t !tr#ct#rall the are not the !ame. 2he &agina ha! a thicY, m#lti*laered celllining that, Qhile not ea!il a"!or"ing !emen from in!ide, i! de!igned toQith!tand friction and !heering force. incl#!ohere, there i! a mechani!m for !ecretion of l#"ricating m#c#! toQith!tand the!e force!. F#rthermore, !emen ha!chemical $ro$ertie! that Qill increa!e the thicYne!! and re!i!tance of thelining mem"rane in the &agina and the !Yinof the $eni! that "ecome! !meared " it. 2he !eminal #id !ecreted Qith the !$erm i! a &er com$le%com$o!ition. It contain! a chemical !#"!tance called

tran!*gl#*tamin*a!e 2EG. In certain circ#m!tance!, 2E "ind! !ome$rotein! to other $rotein!. It al!o ca#!e!!ome cell! to die in a !$ecial QaZto !hri&el and not di!integrate, th#!it! $oQer to $rod#ce a thicYening of the&aginal Qall to co$e Qith normal male*female !e% relation!hi$!. 2hi!$ro$ert of !emen, Qhen introd#ced into theinte!tine, Qill alter the Qater*a"!or"ing (#alit of it! lining, th#! thea!!ociate diarrhea in AID0. 2he !emen al!ocontain! $rotein! Qith e%tremel !trong imm#ne !#$$re!!i&e $ro$ertie!.It i! the imm#ne !#$$re!!i&e $ro$ert of !emen that Qill facilitate the$a!!age of !$erm all the Qa #$ into the

#ter#! and it! t#"e! to fertilie the female egg. 2o the "od, the million!of !$erm that enter the #ter#! are in&adingforeign 7o"ject!7 and Qo#ld "e highl reactionar for the #terine Qalland it! t#"e! had the not "een $rotected "the imm#ne re$re!!i&e $ro$ertie! of $rotein! from the !emen that "athethe !$erm. In order for the !$erm ande&ent#all the fet#! that ha! di[erent antigenic $ro$ertie! to themotherT! ti!!#eG to !#r&i&e d#ring nine month! of$regnanc, the motherT! imm#ne !!tem ha! to "e !#$$re!!ed for thed#ration of $regnanc. /arece (#e!omething in the !emen $o!!i"l a #teroglo"in*liYe $rotein that i! called

0*IG code! for the motherT! imm#ne!#$re!ión.It i! thi! imm#ne*!#$$re!!i&e $ro$ert of !emen that en!#re!the !#r&i&al of initiall the !$erm, and#ltimatel the fet#! d#ring f#ll*term $regnanc #ntil the "irth of a li&ingo[!$ring. It i! intere!ting to YnoQ that in thethird trime!ter of $regnanc there i! often a re&er!al of the 2=42! ratio.0emen in the female &agina i! not a"!or"ed. Beca#!e of the anatomicalde!ign and $o!ition of the &agina, the

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!emen i! drained. 1n the other hand, the rect#m i! lined Qith &er thinand delicate cell!. In the rect#m, !emen i!

retained and it! e%tremel $otent $h!iological $ro$ertie! are alloQedfreedom of action. Sithin the con!tit#ent! of!emen, there are !#"!tance! that are de!igned to o&er taYe the ho!tT!imm#ne !!tem and force them to !h#t doQnthe !ame Qa that a radar jamming de&ice i! #!ed on "oard Qar$lane!to enter enem air!$ace and deli&er their"om"a!.2h#!, !emen ha! an inde$endent a"ilit to !h#t doQn theimm#ne !!tem of it! ho!t ti!!#e if it! agent! arealloQed entr into the reci$ientT! !!tem. Beca#!e of thi! a"ilit, themarYer of 2=42: ratio re&er!al i! !een inhomo!e%#al! Qith AID0.

Sith re$eated !ecretion of !emen into a male or female rect#m, theimm#ne !!tem !#$$re!!ion i! #na&oida"leZnot "eca#!e of a 7&ir#!,7 "#t "eca#!e of chemical $ro$ertie! of the!emen it!elf. Somen Qho $artici$ate in anal !e%to a&oid "ecoming $regnant !ho#ld "e aQare of thi! imm#ne!#$$re!!i&e $ro$ert of !emen.In addition to all of the a"o&e, the inte!tinal Qall i! not ca$a"le of Qith!tanding the force! in&ol&ed in rectalmani$#lation for !e%#al $#r$o!e. 2he rea!on !#ch !e%#al mani$#lation!"ecome $o!!i"le "eca#!e of one !inglefact4 2he inte!tinal tract doe! not ha&e an ac#te $ain !en!or !!tem if 

damaged from in!ide #nle!! the damagea[ect! the $eritone#m, Qhich i! the thin o#t!ide co&er of thega!trointe!tinal tract. It i! am$l !#$$lied Qith ner&e!that Qill regi!ter $ain. It i! a t$e of 7non*adhe!i&e7 that $ermit! &ario#!!egment! of the inte!tinal tract to glide o&erone another in their mo&ement! and d#ring ada$tation to the $a!!age of food. 2he rect#m i! not com$letelco&ered " $eritone#m in the !ame Qa a! the re!t of the inte!tinaltract. 2h#!, the in!ide lining of the rect#m can "ecome damaged from "eing$#m$ed again!t or otherQi!e a"#!i&el

dilated and !t*and*forearm mani$#lated Qitho#t regi!tering thedamage in the !ame Qa the !Yin Qo#ld !o#nd thealarm Qhen it! re!i!tance i! "roYen. 2he rect#m i! the end $art of ananatomical !tr#ct#re Qho!e acti&it ha! to "e$erformed !ilentl. HoQe&er, thi! doe! not mean the damage i! notrecognied $h!iologicall, and it doe! not meanthe $h!iological !te$! for re$air of the local damage Qill "e le!!&igoro#!.

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A! $art and $arcel of the re$air mechani!m!, the chemical agent! 2NF,IL*5, IL*@, and other! in their $acY Qill "e

!ecreted to commence the $roce!! of cri!i! management. If the damagei! !#ch that re!ident "acteria co#ld al!o"reaY "arrier! and "egin increa!ed local acti&it, $rod#ction of the!eagent! for cri!i! management Qill increa!e. 0eha! "een !hoQn e%$erimentall that AID0 $atient! ha&e marYedlincrea!ed le&el! of IL*@ and 2NF in their "lood.G 2hi! rai!ed IL*@, a! it Qa! e%$lained in the !ection on dia"ete!, Qill al!ode!tro the in!#lin*$rod#cing cell! in the$)ncrea!.Hence, a !im$le e%$lanation for dia"ete! !een in the ad&anced!tage! of f#ll*"loQn AID0. 2he!e agent! f#nction &er m#ch liYe a team of !$eciali!t !al&age

QorYer! that go to a !ite after an earth(#aYe.1ne gro#$ Qo#ld clear the de"ri! other! Qo#ld "ring !#r&i&al !#$$lie!for tho!e ca#ght in the area Qho cannot "erelocated another Qo#ld "egin to re!tore $oQer, Qater, and tele$hone!er&ice!, and !o on. In the e&erda life of acit, all the!e $roce!!e! taYe $lace, and the are carried o#t " $eo$leand machine!. In the h#man "od, the !ame$roce!!e! taYe $lace. 2he agent! that $erform the!e nece!!ar f#nction!are hormone! and their !#"ordinateenme !!tem!. 2he $rinci$le i! the !ame. Each cell ha! a $er!onalitand need! to !#r&i&e on the !$ot if it can "e

re$arado.1nl the dead or irre$ara"l damaged cell! Qill ha&e to "edi!mem"ered and cleared aQa.In rectal mani$#lation, !ho#ld there "e more than ro#tine Qear and tear,the!e !ame agent! "ecome o$erati&e! forit! re$air. It Qill taYe time to re$rod#ce the original 7"l#e$rint7 and f#llre!tore local ti!!#e!. 0ho#ld there "e arec#rrence of the inj#r, on to$ of a ti!!#e that i! alread QeaY, moreforcef#l $re!ence of the!e local re$air agent!Qill "e called for. 2here ma come a time that the!e hormone! and their!#"ordinate o$erator! Qill "e $ermanentlcommi!!ioned and their $re!ence in the "lood circ#lation Qill "ecome

mea!#ra"le. 0ince the relation!hi$ and!ignicance of their increa!ed $re!ence for the re$air of the 7#n!en!ed7local damage in the rect#m i! nota$$reciatedZand f#rthermore, the rationale of their acti&it notrecogniedZ$art of their mechani!m of f#nction i!highlighted and la"eled a! the ca#!ati&e factor for the $h!iological#$hea&al that i! con&enientl la"eled a! 7AID07for $#"lic con!#m$tion.

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In la"orator re!earch, it ha! "een !hoQn that c!teine Qill $re&ent the$rod#ction of HI in c#lt#red cell!. En otra

la"orator re!earch, it ha! "een !hoQn that AID0 $atient! are !hort of c!teine and it! $rec#r!or c!tine. In tQo,!im$le*to*#nder!tand e%$eriment!, a meta"olic "a!i! to thede&elo$ment of the di!ea!e ha! "een dearldemo!trado.If the cell! that are !#\cientl a"normal to $rod#ce HI aregi&en c!teine, their a"normalit i!corrected and the do not $rod#ce the HI. All Qe need to YnoQ noQ i!hoQ the!e AID0 $atient! "ecame c!teine*deciente.Se !ho#ld commence the re!earch of thi! $henomenon andnot !idetracY AID0 re!earch into a dead end" maYing a j#m$ of faith and*a!!#ming it to "e &ir#!*$rod#ced.

In m o$inion, it !eem! the 7H2 te!t7 highlight! the $re!ence of afragment of DNA or RNA of a damaged cellZitindicate! a $roce!! of cell n#cle#! "reaYdoQn. It co#ld "e $rod#ced "man other factor!, one of them c!teineand inc decienc, $artic#larl in $eo$le from #nderde&elo$ed and$oorer co#ntrie!. It i! al!o $o!!i"le that it i!ca#!ed a! a re!#lt of $er!i!tent and increa!ingl !e&ere local damage inthe rect#m, $rod#cing a long*term r#n onthe "odT! $rotein re!er&e!. 2hi! te!t " it!elf i! not an acc#rateindicator of the $re!ence of an agent that ca#!e!la enfermedad.2he HI it!elf i! $rod#ced " a more !e&ere im"alance in

the maYe#$ of the amino acid $ool of thec#er$o.It i! thi! de&a!tating amino acid $ool im"alance that Yill! the$atient!, and not the HI $article.A! !oon a! thi! !tatement i! made, man (#e!tion! Qill $o$ #$ in themind! of $eo$le Qho ha&e "een made tofoc#! on HI !$read thro#gh "lood. It i! tr#e the "lood ma contain therelea!ed HI $article! hoQe&er, thi! "loodal!o contain! man other hormone! and tran!mitter!Z!ome not ete&en YnoQn. 1ne can not a!!#me AID0 to "eca#!ed " HI #nle!! the $h!iological e[ect! of the &ario#! othercom$onent! in the !er#m or "lood are YnoQn.

A! a h$othetical e%am$le, 0ir /eter MedaQar, FR0, a No"el la#reate and$re!ident of the Roal 0ociet in Englandha! e%$re!!ed the o$inion that there are certain gene! in the "od that,once triggered into action, Qill $rogram thedeath of the indi&id#al. In other Qord!, e&en death i! an orderl andcontrolled $henomenon. 2he (#e!tion ari!e!4Are the $eo$le Qho lo!e ne gender denition and "ecome di!intere!tedin nat#reT! $rogram of $rocreation more

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!#!ce$ti"le to the acti&ation of the gene! that ca#!e their earl demi!eIn a !erie! of &er !ignicant e%$eriment!, !cienti!t! Brodi!h and

Lmangro&e ha&e !hoQn that 7!tre!!ed inte!tine!7$rod#ce a local hormone that ha! a &er !trong and long*la!ting acti&it.It act! a! a &er $otent corti!one*relea!ingagente.2hi! hormone co#ld "e tran!f#!ed in the !er#m from one animalto another.It !ta! in the neQ animal for!ome time and ha! e%actl the !ame corti!one*relea!ing acti&it.Corti!one*relea!e mechani!m!, at certain le&el!, Qill re!#lt in the$rod#ction of !ome n#cle#! "reaYdoQn and!imilar DNA fragmentation to HI $article formation. Again, thi! i! ameta"olic di!order e&en if the te!t! are$ercei&ed to re$re!ent HI $article formation.

Se !ho#ld #nder!tand that all man#fact#ring $roce!!e! in the cell! of the "od are taYing $lace in a #id medi#m$art! can oat aQa #nle!! an anchoring !!tem i! in $lace. A &erim$ortant $oint that need! clarication i! the factthat man #nit! of c!teine are in&ol&ed in the formation of a t$e of anchoring 7ro$e7 thatha! at !ome !$ecic $oint! inc hooY! attached to a n#m"er of c!teine!that Yee$ the DNA a!!em"l line in$o!ition and $re&ent the drift of it! !egment!, &er m#ch liYe Qa!h line!Qith their hooY! for o$en*air dring ofla ro$a.2he !e% hormone rece$torT! !tr#ct#re, formation, and f#nction in

men and Qomen de$end &er !trongl onthe $re!ence of thi! inc and c!teine 7nger!.7 2h#!, the decienc of c!teine in the "od of tho!e Qith AID0co#ld ha&e a far greater !ignicance than ma "e a$$arent at r!t.Co#ld the lo!! of gender dominance in either !e%"e initiall ca#!ed " change! in the amino acid $ool com$o!ition of the"od, Qith 7com$arati&e7 c!teine, and$o!!i"l inc, decienc at the to$ of the li!t I $er!onall thinY thi! to"e a !trong $o!!i"ilit.Shen o# 7thinY7 Qith o#r head and not o#r heart, o# !ho#ld a!Yo#r!elf4 If the $rimar and initial $ro"lem in

AID0 i! a Qrong mi% of the amino acid com$o!ition in the "od, to the$oint of a[ecting the nat#ral attri"#te! ofgender dominance, i! AID0 $re&enta"le 2he logical r!t !te$ i! a$r#dent correction of the $h!iologicalim"alance, co#$led to the needed ed#cation a"o#t the de!tr#cti&ee[ect! of gi&ing in to homo!e%#ale%$erimentation!. 1ne !ho#ld realie, Qhen the correct mi% of aminoacid! to $rocreate a normal o[!$ring i! not

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a&aila"le to the "od, it! direct i! on the !e% hormone! and theirrece$tor!. 1ne m#!t a!!#me the

decommi!!ioned le!t the nat#ral de!ign of the !$ecie! manGget!dra!ticall changed. It !ho#ld "e remem"eredthe nat#ral de!ign to !e%#alit i! it! o#tcome of $rocreation and rearingof o[!$ring. 2he a!!ociated addicti&e 7high7i! the dri&ing force "ehind the de!ign.NoQ come! a !ocial dilemma If the $re!entl e!ta"li!hed ind#lgence inhomo!e%#al gratication "ecome! agenerall acce$ted norm " !ociet and $arent!, the Qill "e doomingthe $er!on! concerned to a m#ch fa!tereradication from nat#reT! in&entor of it! creation!. 2he nat#ral de!ign of the h#man "od ha! in it! "l#e$rint certain

7dead*end7 direction! the fre(#ent gratication of #nnat#ral rectal!e%#al #rge! i! one of them.B joining !o man di!ea!e condition! " the acronm of AID0, and "getting the $#"lic to thinY of AID0 a! a !ingledi!ea!e $rod#ced " a !loQ &ir#!, m colleag#e! in thi! "ranch of re!earch are doing a di!!er&ice to manYind. ello!!har$l de&iate from the tr#th, and in the $roce!!, !ec#re more re!earchf#nd!, !ell more te!t Yit! and $romote the!ale of $oi!ono#! chemical! that accelerate the deterioration of thehealth of tho!e !o treated.Another (#e!tion that might "e a!Yed concern! the relation!hi$ of 

intra&eno#! mor$hine and heroin #!e to the$rod#ction of AID0. 2he an!Qer ma $o!!i"l "e fo#nd in chemical$ro$ertie! of the!e !#"!tance! on "od$h!iolog. Mor$hine*liYe !#"!tance! regi!ter their e[ect thro#gh thener&e !!tem, Qhich !end! me!!age! aro#nd" the #!e of !erotonin a! it! ne#rotran!mitter agent. 2hi! ner&e !!temand mor$hine*liYe !#"!tance! are a"le toalter the meta"olic $attern of the "od. Endor$hin!, the nat#ralmor$hine! of the "od, not onl !#$$re!! $ain!en!ation and $rod#ce e#$horia, the al!o alter the le&el of h#nger!en!ation. /eo$le Qho #!e mor$hine and heroin

lo!e their a$$etite and do not !eem to eat $ro$erl. 2he "egin to feedo[ their oQn "od.F#rthermore, tho!e Qho #!e the!e dr#g! on a reg#lar "a!i! are highl!tre!!ed $eo$le, either " the initial rea!onthat forced them to taYe dr#g!, or " the di\c#lt of getting a reg#lar!#$$l. In an e&ent, !tre!! $h!iolog !et! in,and "eca#!e of altered meta"oli!m, not eno#gh of the "odT! dailneed! Qill "e a&aila"le. Shen mor$hine or

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heroin i! #!ed, the !en!ation! of h#nger and thir!t are al!o !#$$re!!ed,and the "od "egin! to feed o[ it!elf. en

co#ntrie! Qhere $eo$le #!ed to !moYe o$i#m, a great n#m"er of the!e$eo$le e&ent#all died of l#ng infection!Ze%actl Qhat i! noQ "lamed on the &ir#! and contaminated needle!.It i! al!o im$ortant to YnoQ there i! a time ga$ of man ear! "etQeenrecognition of 7HI7 in the "od and$rod#ction of clinical !m$tom! of imm#ne !#$$re!!ion. I can a!!#reo#, the amino acid im"alance d#ring thi!time ga$ "ecome! a far more $otent Yiller than the 7&ir#! of AID0.7 Atthe "eginning, the "od "egin! to $rod#ceanti"odie! to the &ir#!. It i! onl after !ome time that $rod#ction of allanti"odie! "ecome! in!#\cient and

ineca.Se !ho#ld remem"er that a "alanced and Qell*$ro$ortionedamino acid $ool com$o!ition in the "od i!a"!ol#tel e!!ential for anti"od $rod#ction " the Qhite "lood cell! andthe li&er cell!.1ne terri"le a!$ect of AID0 i! the cr#elt Qith Qhich it a[ect! "a"ie!"orn to mother! Qho are H2 $o!iti&e. lo!ho#ld "e clear, if the mother i! decient in certain amino acid! in her"od, !he i! not a"le to $ro&ide the "a" Qiththe correct range of amino acid! for it! normal de&elo$ment. 0ho#ld themother "e e&en minimall decient in hermethionine, c!tine, c!teine, tr$to$han and other!, the "a" i! "o#nd

to "e !hort of the!e !ame element! that Qill$o!!i"l $redi!$o!e to DNA fragmentation in the $roce!! of cellde&elo$ment, $artic#larl in the "rea!t*feeding$ha!e of the childT! de&elo$ment. 2HE UNF1LDIN 1F EEN20 IN AID0 RE0EARCHA! thi! "ooY Qa! "eing Qritten, a gro#$ of !cienti!t! in AID0 re!earchfrom E#ro$e and America gathered inHolland in Ma of 5??; to "egin a mo&ement again!t the e!ta"li!hedand $rotected thinYing on AID0 a! a &iralenfermedad.A! re$orted in the London 0#nda 2ime! of ;@ A$ril 5??;,tQo of the mo!t intere!ting mem"er! of thi!

gro#$ Qere /rofe!!or L#c Montagnier from France and /rofe!!orD#e!"erg from America./rofe!!or L#c Montagnier of the /a!te#r In!tit#te i! the originaldi!co&erer of the &ir#! that Qa! later la"eled a!H2.2hi! French $rofe!!or i!olated the claimed &ir#! that Qa! !#$$o!edto ha&e inhi"ited the imm#ne !!tem. 'l!ent !am$le! of the &ir#! to Ro"ert allo in America, Qho Qa! al!oQorYing on a method for i!olation and te!ting of

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an AID0 &ir#! in the "od. Dr. allo later a$$lied for a $atent on a te!tYit. 2he French go&ernment !tarted legal

$roceeding! to claim it! right! for the di!co&er of the &ir#!. E&ent#alland after m#ch legal ha!!le, the tQo $artie!agreed to !hare a $ortion of the $roceed! from the marYeting of the te!tYit. 2he re!t of the $roceed! go to f#rtherre!earch of AID0. B#t the French Qo#ld not remain (#iet and forcedf#rther in&e!tigation! into the allegation! of!cientic im$ro$riet. After a more thoro#gh !cr#tin, it ha! noQ "eenconceded that Dr. allo had initiall #!ed theFrench !am$le for hi! $atent./rofe!!or Montagnier !eem! to ha&e re&er!ed hi! original &ieQ! and noQclaim! the &ir#! not to "e of $rimar

im$ortance in AID0. 2he neQ!$a$er inter&ieQ indicate! that the$rofe!!or noQ acce$t! the $o!!i"ilit of AID0ha&ing other ca#!e!. He !eem! to acYnoQledge the $o!!i"le e%i!tence of AID0 e&en Qitho#t the $re!ence of HI. 2he $rofe!!or m#!t ha&e come acro!! com$elling arg#ment! that denHI a! the c#l$rit and the !ingle ca#!e of allthe gro#$ of di!ea!e! cla!!ied #nder AID0. A dra!tic change ha! taYen$lace in /rofe!!or MontagnierT! thinYing./rofe!!or D#e!"erg, Qho had re!earched the act#al com$o!ition of the&ir#!Zat the !ame time a! other! Qere"elie&ing in it! di!ea!e*$rod#cing $ro$ertie!Zhad anno#nced the &ir#!

inca$a"le of ca#!ing AID0. ha"+aman de"ate!, "#t hi! arg#ment! did not c#t an ice Qith thee!ta"li!hed gro#$ "#! Qith AID0 &iral re!earch inAmerica and in E#ro$e. He co#ld not o[er an alternati&e !cientice%$lanation on the ca#!e of the di!ea!e!gro#$ed together #nder AID0 other than !aing the di!ea!e i! notca#!ed " a &ir#!. 2he re!earcher! in thi! eldQere looYing for $la#!i"le !cientic idea! to nd a !ol#tion to the$ro"lem. A !tatement to the e[ect that AID0 i! nota &iral di!ea!e Qa! not eno#gh. 0cientic rea!on! Qhich $oint in anotherdirection !ho#ld ha&e accom$anied the

negation of HI a! the ca#!e of the di!ea!e.I Qrote to Dr. Manfred Eigen, a mo!t eminent DNA re!earch !cienti!tfrom Ma%*/lancY In!tit#te in erman, on ;90e$tem"er 5?:?, and in defen!e of D#e!"erg !ent him tQo of marticle! $re!enting mo!t of the &ieQ! that Qere$#"li!hed in the Fo#ndationT! 0$ecial AID0 I!!#e. Dr. Eigen had $#"li!hedan acco#nt of di!c#!!ion! "etQeen

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AID0 &ir#! ad&ocate! and D#e!"erg in Nat#r Sei!!en!chafen. It !eem!Dr. Eigen Qa! not con&inced " /rofe!!or

D#e!"ergT! &ieQ! and had taYen the !ide of the o$$o!ition. A feQmonth! later, Dr. Eigen !ent me a letter that!hoQed he noQ realied another $la#!i"le !cientic &ieQ on the ca#!e of AID0 doe! e%i!t.NoQ, all of a !#dden in 5??;, a neQ !#rge of acti&it Qith an alternati&e&ieQ of AID0 had gathered moment#m Qith"oth /rofe!!or! Montagnier and D#e!"erg a! leader! in the eld.In 5?:?,5 had !ent the!e re!earcher! a co$ of o#r 0$ecial AID0 I!!#e of 0cience In Medicine 0im$lied 0M0Gfrom the Fo#ndation for the 0im$le in Medicine reference! <= and <9G,in the !ame Qa the Fo#ndation freel

!hare! it! &ieQ! Qith mo!t to$ re!earcher! a co$ of the letter toManfred Eigen Qa! al!o !ent to /rofe!!orD#e!"ergG. 2hi! !$ecial AID0 &ol#me Qa! al!o !ent to man medicalli"rarie! at #ni&er!itie! engaged in AID0in&e!tigación.2he detailed article! $re!ented !cientic e%$lanation! fromQhich a !no$!i! ha! "een gi&en in the$receding $aragra$h!.In m article on the ne#rotran!mitter hi!tamine, r!t $re!ented "rie atthe 8rd Inter!cience Sorld Conference onInammation in 5?:?, and later $#"li!hed in 5??>,5 al!o e%$lained theimm#ne !#$$re!!i&e action! of man of the

chemical agent! that are generated a! a re!#lt of !tre!! in the h#man"od. In thi! e%ten!i&el di!tri"#ted article, Idi!c#!!ed !ome a!$ect! of AID0 a! a !e&ere !tre!!*ind#ced 7!!temdi!t#r"ance,7 o$$o!ing the c#rrent &ieQ that iti! ca#!ed " a !ingle $article, a &ir#!. 2hi! i!!#e of 0M0 Qa! al!o e%ten!i&el di!tri"#ted. Co$ie! of the 5?:?0$ecial AID0 I!!#e and 5??> i!!#e of 0M0Qere al!o !ent to /rofe!!or /hili$$e Laar, the Director eneral of IIN0ERM in France. IN0ERM i! the Frenche(#i&alent of the NIH in America. He Qa! a!Yed to maYe the informationcontained in the!e i!!#e! of 0M0 a&aila"le

to other intere!ted !cienti!t! at IN0ERM.M re!earch Qa! $rogre!!ing at the !ame time a! neQ information onthe critical role! of c!teine in theman#fact#re of !ome DNA material! "ecame a&aila"le and $#"li!hed. It"ecame com$letel clear and o"&io#! tome that AID0 Qa! a meta"olic di!order, and the DNARNA fragment!cla!!ied a! the di[erent &ir#!e! of AID0Qere them!el&e! a $rod#ct of c!teine !hortage in the "od.

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Sith innitel more detail than ha! "een $re!ented in thi! !ection, mmo!t recent article, 7AID04 2he Dead*End of

ir#! Etiolog7 Qa! $#"li!hed in the 5??5 i!!#e of 0M0 and di!tri"#ted toman other !cienti!t! engaged in thi! eldof re!earch.It i! a moral o"ligation of an dedicated !cienti!t to !hare hi! or her neQinformation Qith other! engaged in there!earch of a common to$ic, e&en "efore the !#"ject i! $re!ented in!cientic jo#rnal!. It i! al!o a moral o"ligationof tho!e Qho recei&e the information to gi&e credit to the $er!on Qhoha! generated and !hared the information.A neQ! headline in Le Monde of ? A#g#!t 5??5 reected a heated ght"etQeen Br#no D#rie#%, the Mini!ter of

Health of France and /rofe!!or Al"ert erman, /re!ident of the NationalAcadem of /harmac of France. lamini!ter had demanded the di!mi!!al of the $rofe!!or. 2he $rofe!!orhad, in an addre!!, gi&en the o$inion thatAID0 i! ca#!ed a! a re!#lt of a $artic#lar life !tle. 2he $rofe!!orT!o$inion had "ecome a hot i!!#e among thedi[erent !ocial gro#$!. 2h#! the Qrath of the mini!ter and the demandfor hi! di!mi!!al. No occa!ion lend! it!elf"etter to the introd#ction of an e%$lo!i&e o$inion than adding it a! f#elto an alread e!ta"li!hed (#arrel. La carta$rinted in the ne%t $age Qa! !ent to M. Br#no D#rie#%, Mini!ter of Health

of France, Qith a co$ to /rofe!!orAlem)n.A MEDICAL RE0EARCH IN02I2U2I1N/.1.B1 8;@<FALL0 CHURCH A ;;>=8 U.0.A.E%c.M. Br#no D#rie#%Mini!ter of Health 5 /lace de Fonteno <989> /ari! ><*0.R@ 0e$tem"er 5??5E%cellence,I ha&e "een e%$o!ed to the to$ic of o#r di!c#!!ion a"o#t the &ieQ! of /rofe!!or Al"ert erman on AID0, reected

in Le Monde, ? A#g#!t 5??5. I tho#ght it m re!$on!i"ilit to "ring too#r attention the nal re!#lt of o#r &ere%ten!i&e re!earch into the etiolog of AID0. 1#r re!earch !eem! to$rod#ce $h!iologic meta"olic e%$lanation!that !#$$ort the &ieQ! of $rofe!!or erman. I ha&e $lea!#re in enclo!inga co$ of o#r recent article, 7AID04 2heDead*End of ir#! Etiolog.7 2he article e%$lain! detail! that ha&e "eenignored " tho!e Qho Qi!h to force a

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!ol#tion to the $ro"lem thro#gh &iral re!earch * a total Qa!te of $#"licf#nd!. Oo# are Qelcome to ha&e the article

$hotoco$ied and re&ieQed " an n#m"er of o#r !cienti!t! Qho do notdemon!trate a "lind "ia! toQard &iralin&e!tigación.If more information i! needed, $lea!e do not he!itate tocontact me.Atentamente,R Batmanghelidj, M.D.Enclo!#re4 Article, AID04 2he Dead*End of ir#! Etiolog. Co$, /rofe!!orAl"ert erman.I !incerel ho$e that the free !haring of m re!earched &ieQ! on AID0ha! in !ome Qa "een in!tr#mental in gettingother! to thinY a"o#t the relation!hi$ of thi! di!ea!e condition to an

a"normal $h!iolog that "ecome! #ltimatele!ta"li!hed a! a re!#lt of 7!tre!!e! a!!ociated Qith a $artic#lar life!tle,7 or 7!e&ere maln#trition in le!! fort#nate!ocietie!.7 2he children in Romania that Qere the !#"ject of mantele&i!ion $rogram! mo!t $ro"a"l did not getAID0 from "lood contamination the more than liYel de&elo$ed AID0 a!a re!#lt of maln#trition.Another $oint that need! to "e di!c#!!ed i! the &al#e of the AID0 te!t a!an indicator of a di!ea!e in the $roce!! ofde!arrollo.Altho#gh e&erone i! led to "elie&e thi!, it i! in m o$inion anerroneo#! re$re!entation of a di[erent

&erdad.All thi! te!t !hoQ! i! that the "od ha! come acro!! thi!antigenic $article and ha! regi!tered it! !tr#ct#re. loal!o mean! the "od ha! Ye$t the e%i!tence of thi! $article&ir#! in it!memor*"anY to man#fact#re a defen!emechani!m again!t the 7foreign $article,7 not nece!!aril a $article fromo#t!ide, "#t a $article that the "od it!elf!ho#ld not maYeZa form of (#alit control at the 7DNA a!!em"l line.7 2hi! te!t i! #ltimatel an indicator of a "odT!amino acid meta"oli!m di!t#r"ance, and not an indicator of a loo!e Yiller&ir#! in the "od. El n-mero de $r#e"a!$o!iti&e ca!e! Qho "ecome HI negati&e are too man to "e ignored.

It ha! "een !hoQn in la"orator e%$eriment! that if c!teine i! added toa c#lt#re medi#m that i! groQing cell! for&ir#! $rod#ction, the!e cell! Qill not man#fact#re the 7&ir#!.7 In amedi#m Qith !#\cient c!teine, it Qill not "e$o!!i"le to har&e!t the &ir#!. 2hi! te!t $re!ent! the mo!t clearconcl#!ion that the AID0 te!t i! onl an indicator ofan on*going amino acid im"alance in the "od. It i! im$ortant toremem"er that if the le&el of one amino acid in the

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"od i! not eno#gh, then a dra!tic im"alance in the $ercentagecom$o!ition of the other amino acid! al!o Qill e%i!t.

 2he!e neQ idea! on AID0 are $re!ented to the reader! of thi! "ooY toindicate that a meta"olic a$$roach to dealingQith thi! !ocial $ro"lem Qill $rod#ce more !ati!factor and (#icYerre!#lt!. A $r#dent correction of the initialmeta"olic im"alance might "oo!t the e%$re!!ion! of normal genderdenition and decrea!e homo!e%#altendencie!, not to mention $re&enting AID0, $artic#larl in tho!e Qhode&elo$ homo!e%#al tendencie! in the laterear! of life, !#ch a! father! or mother! Qith Yid!, Qho "egin to feelhomo!e%#al $#ll!. In Qomen Qho "egin to lo!eli"ido and lo!e hair Qith a 7male $attern7 di!tri"#tion, the a"o&e

$reca#tionar mea!#re! might arre!t !#ch a declineat it! earl !tage!.An ea! Qa to !to$ m#!cle "reaYdoQn i! " an intelligent adj#!tment of the dail Qater intaYe and " eating a"alanced high*$rotein diet. 2aYe a looY at EdQard Di$$reT! letter on $age59>. A! o# can !ee, Qater and !ome !altintaYe ha&e re&er!ed m#!cle "reaYdoQn in a dehdration*$rod#ced7di!ea!e7 condition. Not YnoQing the ca#!e, the$ro"lem ha! "een la"eled a! m#!c#lar d!tro$h.Enhancing dail e%erci!e and $h!ical acti&it at the !ame time Qo#ldforce the "od into a $h!iological $rogram to

"#ild #$ it! m#!cle!, in!tead of "reaYing them into their amino acidcom$onent! to feed the re!t of the "od. #!tedneed to realie the h#man "od i! de!igned to defend it!elf again!t allt$e! of infection!. It !#r&i&ed fa!t acting&ir#!e! !#ch a! !mall$o%, mea!le!, $olio, and other! d#ring it!de&elo$ment. It generall taYe! the "od a"o#t nineda! to mo#nt an e[ecti&e defen!e again!t e&en fa!t &ir#!e!. If the "odcan !#r&i&e fa!t &ir#!e!, !#rel it i! morethan ca$a"le of defending it!elf again!t !loQl groQing &ir#!e!.All that Qe need to #nder!tand i! hoQ to maYe the "od !tronger and!to$ action! that Qo#ld maYe it &#lnera"le.

Let #! remem"er, if the camel had a "acY*"reaYing $oint to the Qeightof the la!t !traQ, !#rel the h#man "odm#!t al!o ha&e a $h!ical "reaYing*$oint to "eing life*!tli!hlo&erloaded 2he (#e!tion i!, do Qe contin#e tomea!#re the !traQ or the inherent !tr#ct#ral and $h!iologicallimitation! Do Qe $a attention to the limitation! ofthe "od, or do Qe in carefree a"andon "lame an ine[ecti&e !loQ &ir#!for the ill! that "efall !ome mem"er! of o#r

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!ocietEdQard Di$$re

;5< North 0treetSe!t /itt!ton, /a. 5:@=8March 59,5??9lo"al Health 0ol#tion!co Dr. Batmanghelidj/.1.Bo% 85:?Fall! Ch#rch, a. ;;>=8Dear Dr. BatmanghelidjAro#nd No&em"er 5 m leg! Qere gi&ing o#t. 2he "ecame "lacY and"l#e from m Ynee! to m thigh!, and &erdoloro!a.I Qent to the doctor and he told me that m m#!cle enme!

Qere at @@> and normal Qa! ?>. 2hen I Qent toanother doctor and he !aid that I had m#!c#lar d!tro$h.I !tarted talYing to Dr. Batmanghelidj Qho told me to !tart drinYing ;(#art! of Qater dail. I ha&e "een, I feel m#ch"etter, and all !m$tom! di!a$$eared in tQo month!. I al!o #!e !ea !altli"erall Qith all m meal!.I Qent "acY to the doctor and had additional SoodQorY done. 2heenme le&el! in m m#!cle! Qere "acY tonormal, and the doctor co#ldnTt #nder!tand hoQ it Qa! $o!!i"le.A! of thi! date, March 59,5??9,5 am free of all di!comfort and!m$tom!. I al!o ha&e more energ and "etter health

than I can remem"er for a long time.EdQard Di$$re 2HE 0IM/LE02 1F 2REA2MEN20 IN MEDICINE7Oo# cannot " rea!oning correct a man of ill o$inion Qhich " rea!oninghe ne&er ac(#ired.7 ZBacon Oo#r "od need! an a"!ol#te minim#m of !i% to eight :*o#nce gla!!e! of Qater a da.Alcohol, co[ee, tea, and ca[eine*containing "e&erage! donTt co#nt a!Qater. 2he "e!t time! to drinY Qater clinicall o"!er&ed in $e$tic #lcer di!ea!eGare4 one gla!! one half ho#r "efore taYing

foodZ"reaYfa!t, l#nch, and dinnerZand a !imilar amo#nt tQo and onehalf ho#r! after each meal. 2hi! i! the &erminim#m amo#nt of Qater o#r "od need!. For the !aYe of not!hortchanging o#r "od, tQo more gla!!e! ofQater !ho#ld "e taYen aro#nd the hea&ie!t meal or "efore going to "ed. 2hir!t !ho#ld "e !ati!ed at all time!. Sith increa!e in Qater intaYe, thethir!t mechani!m "ecome! more e\cient. Oo#r "od might then a!Y o# to drinY more than the a"o&e minim#m.

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Adj#!ting Qater intaYe to mealtime! $re&ent! the "lood from "ecomingconcentrated a! a re!#lt of food intaYe.

Shen the "lood "ecome! concentrated, it draQ! Qater from the cell!aro#nd it.Sater i! the chea$e!t form of medicine to a dehdrated "od. A! !im$la! dehdration Qill in time $rod#ce themajor di!ea!e! Qe are confronting noQ, a Qell*reg#lated and con!tantlalert attention to dail Qater intaYe Qill$re&ent the emergence of mo!t of the major di!ea!e! Qe ha&e come tofear in o#r modem !ociet.Silliam raT! letter i! introd#ced here a! an e%am$le of hoQ !im$lQater i! a "etter medication for the treatmentof !o man di[erentl la"eled com$lication! of chronic dehdration. Hi!

letter had to "e t$ed into thi! !egment ofthe "ooY "eca#!e the original co#ld not t in thi! $age !ie. A! o# Qill!ee, Mr. ra i! a highl intelligent $er!on.Hi! o"!er&ation! $ro&ide a great deal of in!ight into the $o!!i"lecom$lication! of chronic dehdration in the h#manc#er$o.For thi! rea!on I !elected thi! !ection of the "ooY to $re!ent too# hi! o"!er&ation!.M ho$e i! to im$re!!#$on o#r mind a !im$le fact. 2here i! more nat#ral magic in a gla!! f#llof Qater than an medication o# are"rainQa!hed to #!e for the treatment of the condition! I ha&e e%$lainedin thi! "ooY. And I do not !ell Qater

From4 Silliam E. ra BillG=55 Arhill A&en#eienna, A ;;5:> 55*;*?=<>8*?8:*@88> 2o4 Dr. Batmanghelidj;5=@ King! arden SaFall! Ch#rch, A ;;>=8It ha! "een one ear !ince I r!t read o#r "ooY, Qhich Qa! gi&en to mea! a $re!ent " Marcel 2he&o. De!de entonce!m health ha! im$ro&ed !ignicantl. lam noQ 9; and in e%cellenthealth. 2hi! Qa! not the ca!e "efore o#r "ooY

and MarcelT! Yindne!! in!$ired me to maYe Qater an integral $art of mlife. 2o mo!t $eo$le J Qa! !#cce!!f#l and in e%cellent health * normal Qeight,#n#!#al !trength and end#rance, a"o&ea&erage at !$ort!, Qith an e%cellent diet a lot of fre!h &egeta"le! andQhole grain! and &er little meat, animal$rod#ct! or $roce!!ed foodG. Oet m li!t of com$laint! !tretche! o&er thela!t ft ear! and incl#de!4 d#odenal

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#lcer age 5?G, indige!tion, colon and elimination $ro"lem! age 5? to95G, food allergie! age 5; to 5<G, chronic

!in#! infection age 9 to 95G, chronic and ac#te "acY $ro"lem! age 58thro#gh age 95G, emotional illne!! andmental conf#!ion age @ to age 95G. 2he!e $ro"lem! Qere e&en more "eQildering and conf#!ing "eca#!e lamintelligent, ed#cated and moti&ated to nd!ol#cione! a lo! $ro"lema!.I ha&e "een !earching for an!Qer! to the!e$ro"lem! for 89 ear!.I ha&e looYed for an!Qer!in4 diet, diet !#$$lementation, e%erci!e, oga, meditation, 2raditionalReligion, !$irit#al $ractice!, Ac#$#nct#re,traditional medicine, Chiro$ractic, Ma!!age, RaYi, /olarit Balancing, 5;0te$ $rogram!, and !elf im$ro&ement

"ooY! and co#r!e!, !#ch a! E!t and the Ho[man P#adrinit /roce!!.I had of co#r!e read man time! a"o#t the im$ortance of drinYing $lentof Qater. I e&en in&e!ted in re&er!eo!mo!i! Qater lter @ ear! ago ho$ing that the im$ro&ed ta!te of theQater Qo#ld moti&ate me to drinY more Qater.In !$ite of thi! I ne&er ga&e Qater thera$ a fair chance. Until I read o#r"ooY, other "e&erage! alQa! looYed"etter to me, $artic#larl tea and co[ee.At the time I read o#r "ooY I had a chronic ner&e inj#r in m #$$er"acY that intermittentl $re&ented me from$laing golf or racYet "all for a $eriod of tQo ear!. M arm !trength Qa!

58 of Qhat it had "een onl ; ear!$re&iamente.I Qa! at a loQ $oint in m life $h!icall and mentall.I ha&e ne&er "een dr#nY in m life or !moYed more than 9 cigarette! in ada. At the time I Qa! not !moYing ordrinYing alcohol. Oet I fo#nd m!elf o"!e!!ed Qith tho#ght! of ca[eine,!moYing and drinYing. Altho#gh I ha&e "eena fre(#ent &i!itor at Chiro$ractic, 1!teo$athic and Ma!!age thera$i!t!, Ihad not needed to &i!it medical doctor forao.In m de!$eration I Qent to an MD Qho $re!cri"ed an anti*!tre!!medication, a $ain relie&er, and a m#!clerela%ant.I tooY the $re!cri"ed do!e! and fell into a !emi coma for 5@

ho#r!, and di!contin#ed the medication. alg#no!QeeY! later Marcel came to m home for dinner and ga&e me o#r "ooY.Sithin one QeeY of adding ;*8 (#art! of Qater to m diet noticed I that4_ 2he $ain from the ner&e inj#r Qent aQa and I Qa! a"le to "egine%erci!ing._I had m#ch le!! indige!tion and ga!._M #rge! and com$#l!i&e "eha&ior le!!ened !#"!tantiall or &ani!hed. Ino longer had to ght the #rge to !moYe,

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drinY, !t#[ m!elf or #!e e%ce!!i&e ca[eine._ M energ le&el! im$ro&ed.

_ M thinYing and QorY im$ro&ed./lea!e feel free to #!e me a! a reference. I am ha$$ to talY to anonea"o#t Qater at an time.Silliam E. ra1rdinar ta$ Qater, #nle!! there i! $roof of it! "eing contaminated Qithchemical! and hea& metal! !#ch a! lead, i!a good !o#rce of !#$$l. 2a$ Qater ha! the $rotection of chlorine a! a"acteria*Yilling agent. 2he 7"ottled Qater7 in!#$ermarYet! i! !aid to "e !terilied " the addition of oone at the timeof "ottling. 1one, or 7!#$er o%gen,7!eem! to ha&e a "acteria*Yilling $ro$ert. If #!ed in time, "ottled Qater

can !er&e a! an alternati&e !o#rce of !#$$l.If o# are not !#re of o#r Qater !o#rce not "eing contaminated orcontaining im$#ritie! not !afe to drinY, !a&eo#r!elf from thi! an%iet " in!talling a !mall ltration #nit on o#rYitchen fa#cet. 2here are &er e[ecti&e car"on orceramic lter #nit! that can !a&e o# from the ha!!le of "#ing Qaterfrom the !tore! and ha&ing to carr it!container! da in and da o#t.E&ent#all, the 7$oint of #!e7 ltration of Qater Qill "ecome !tandard$ractice in ad&anced !ocietie! that ha&e atendenc to $oll#te their drinYing Qater. Sith the $re!ent decline in the

fort#ne! of the m#nici$alitie!, deli&ering(#alit drinYing Qater in their $i$e !!tem! Qill at one $oint "ecome tooe%$en!i&e and im$o!!i"le. It Qo#ld not "e$ractical to deli&er high (#alit Qater to al!o #!e for Qa!hing andgardening.HoQe&er, Qhen one de&elo$! a ta!te for other than ta$ Qater, if oner#n! o#t of !#$$l in the ho#!e, the "od Qill "eforced to go Qitho#t Qater j#!t "eca#!e of the di[erence in ta!teZa !elf*im$o!ed $reference. U!#all, the 7"adta!te7 i! attri"#ted to di!!ol&ed chlorine in the Qater. Mo!t !ale! agent!Qho Qi!h to !ell Qater $#rier! maYe i!!#e

of the fact that ta$ Qater contain! chlorine. 2he al!o $oint to calci#mdi!!ol&ed in the Qater, often called 7hardQater.7If Qe ll an o$en*to$ j#g Qith Qater and let it !tand in the refrigerator oron the Yitchen co#nter, the chlorine that i!di!!ol&ed in the Qater Qill e&a$orate and the !mell of it Qill go too. 2heQater Qill "ecome 7!Qeet7 and &er ea!il

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a$eteci"le.2hi! i! hoQ all re!ta#rant! !er&e QaterZo#t of a Qell*iced j#gthat Qa! lled !ome time "efore it! #!e. como

for the calci#m in the Qater, #nle!! the Qater i! tr#l and hea&ilcalci#m*laden, it! #!e i! $erfectl !afe. Not onl i! it!afe, it i! a chea$ !o#rce for calci#m need! of the "od. 2he calci#m i!alread di!!ol&ed in the Qater and one doe!not need to go to the $harmac to "# calci#m ta"let! to taYe a! a$re&enti&e mea!#re again!t the o!teo$oro!i! Qe!ee in the elderl.HoQ and Qhen do o# thinY o!teo$oro!i! "egin! Act#all, man ear!"efore it i! recognied. Shen hdroelectricenerg !tore! "ecome de$leted on and o[, energ !tored in the "ondageof calci#m to calci#m in the cell! and

e&ent#all in the "one! i! #!ed. Shen one molec#le of calci#m "ecome!!e$arated from another molec#le ofcalci#m, one #nit of A2/ i! al!o relea!ed. A2/ i! one #nit of e%changea"leenerg. 2he loo!e calci#m i! noQa&aila"le to "e !hed. Shen Qater and calci#m are taYen in their nat#ralform!, the emergenc need for the relea!eof energ !tored in calci#m "ondage i! decrea!ed.2hi! i! Qh "one! area great !o#rce of re!er&ed energ. la"od i! a"le to ta$ into thi! re!er&oir of energ.In an ca!e, e&en hea&il di!!ol&ed calci#m in the Qater Qill mo!t$ro"a"l "e Qitho#t ad&er!e e[ect!. Al $arecer, el

"od $o!!e!!e! a mo!t delicate need*reg#lated mechani!m of a"!or$tion of element! from the ga!trointe!tinaltracto.Mo!t $ro"a"l, not all the calci#m di!!ol&ed in e&en &er hardQater enter! the !!tem.A recent !t#d inanother co#ntr and in a region Qith onl &er hard Qater a&aila"le forcon!#m$tionG ha! !hoQn the calci#m*ladenQater con!#med did not $rod#ce an ad&er!e e[ect! on the $eo$le Qhodid not a&oid drinYing the Qater.In thi! a$$roach to di!ea!e $re&ention, one Qill not need to !ticY to a!trict diet mani$#lation to control thi! or thatclinical condition a! long a! Qater intaYe $recede! food intaYe. HoQe&er,

one Qord of ad&ice i! to limit fatt and friedfood!. Fat! get con&erted to fatt acid! and circ#late in the "lood. Fattacid! Qill re$lace tr$to$han that i! attachedto the al"#min to "e !tored and $rotected Qhile "eing circ#lated aro#ndin the "lood. 2he li&er Qill attacY and de!trofreed tr$to$han if it! free form in circ#lation i! more than ;> $ercent of it! total content. In d#e time, e%ce!! fatt

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food Qill de$lete the tr$to$han re!er&e! of the "od. 2hi! i! one of themo!t im$ortant rea!on! Qh fatt food! are

not good for health.At the !ame time, not all fatt acid! are "ad for the "od. In fact thereare at lea!t tQo e!!ential fatt acid! that the"od need! all the time and cannot man#fact#re. 2he are4 Al$halinoleicAcid, LNA, YnoQn a! 1mega 8 oil, andLinoleic Acid, LA, YnoQn a! 1mega @ oil. 2he!e fatt acid! are needed forthe man#fact#re of cell mem"rane!T,hormone! and ner&e co&ering! in the "od. Altho#gh other fat! thatenter the "od are #!ed for their energcontent, 1*8 and 1*@ are !a&ed and onl #!ed for the man#fact#re of hormone! and in the !tr#ct#re of all of the

mem"rane! in!ide and co&ering the cell. In treatment of the di!ea!e!that are $rod#ced " the damage to the ner&eco&ering $age @8G, the reg#lar intaYe of the!e e!!ential fatt acid! i! am#!t. 2he riche!t !o#rce of 1*8 i! a% !eed, from Qhich a% oil i! e%tractedand !old on the marYet. Fla% oil al!o contain!!ome 1*@ in it! com$o!ition. 2he riche!t !o#rce! of 1*@ are !a]oQer and!#noQer oil!. Fla% oil i! alread on themarYet. UdoT! Choice Qill come to the American marYet !oon. Dr. UdoEra!m#!, the a#thor of the "ooY, Fat! 2hatHeal Fat! 2hat Kill and "a!ed on man ear! of re!earch, ha! de&elo$ed

a !$ecial mi% of the e!!ential oil! the "odneed! for it! di[erent man#fact#ring $rogram!. UdoT! Choice contain!4a% oil, !#noQer oil, !e!ame oil, rice germoil, Qheat germ oil, oat germ oil, lecithin, &itamin E, and !ome !$ecialtriglceride!. 0i% to eight gram! a !$oonf#lG ofthi! mi% dail !ho#ld $ro&ide all the e!!ential fatt acid! that the "odneed!. For more information on oil!, read hi!li"ro.Lo!! of hair, !terilit, QeaYne!!, im$aired &i!ion, groQth retardation,ecema, li&er damage, Yidne damage, andother degenerati&e condition! ma al!o "e a!!ociated Qith e!!ential

fatt acid decienc in the "od.EA0E 1F 0LEE/IN4Are o# ha&ing di\c#lt in !lee$ing at night 2r drinYing a gla!! of Qater and then $#tting a $inch of !alt on o#rtong#e. M $er!onal e%$erience, and o"!er&ation in other!, ha&e !hoQnthat one "egin! falling a!lee$ Qithin a feQmin#to!.In m e!timation, thi! com"ination alter! the rate of electricaldi!charge in the "rain and ind#ce! !lee$.

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Remem"er not to to#ch the $alate Qith the !alt. It ma ca#!e irritation.A c#$ of og#rt at night "efore going to !lee$

Qill al!o hel$. It QorY! a! if o# ha&e taYen a !lee$ing $ill./REEN2 FAIN2IN4If o# are !#!ce$ti"le to feeling faint after a !hoQer, "egin to recogniethat the Qater re!er&e! of o#r "od are noteno#gh to reach o#r "rain Qhen the "lood &e!!el! in the !Yin o$en #$"eca#!e of the heat from the hot !hoQer.AlQa! drinY Qater "efore going #nder the !hoQer. DrinY more Qater andincrea!e o#r !alt intaYe if o# feel faintQhen o# !tand #$./REEN2 A HEAR2 A22ACK4A friend of mine i! noQ in ho!$ital, ha&ing had a heart attacY folloQed "

heart arre!t. He had colla$!ed in hi! o\ceand had to "e re!#!citated to "egin "reathing again. He noQ ha!ne#rological com$lication! "eca#!e no o%genhad reached hi! "rain Qhen hi! heart !to$$ed "eating. It i! noQ clearfrom the famil that for a n#m"er of da! $riorto hi! attacY, he had niggl che!t $ain! that $rojected into hi! left arm.He $aid no attention to it thinYing it Qo#ld goaQa " it!elf. Hi! mi!taYe ha! landed him and noQ hi! famil into greatemotional and $o!t*!troYe n#r!ing$ro"lema!.If he had learned that anginal $ain that $roject! into the arm i! a late

com$lication of chronic dehdration, and if hehad !tarted increa!ing hi! dail Qater intaYe, he mo!t $ro"a"l Qo#ldnot ha&e !#[ered from !#ch cata!tro$hic andirre&er!i"le damage. /lea!e, for the !aYe of tho!e Qho lo&e and care foro#, remem"er to increa!e o#r dail QaterintaYe if o# are e%$eriencing anginal $ain. Oo# !ho#ld al!o "egin toe%erci!eZQalY, QalY, QalYC1L1R 1F URINE4 2he normal color of #rine !ho#ld not "e darY. It !ho#ld ideall "e almo!tcolorle!! to light elloQ. If it "egin! to"ecome darY elloQ, or e&en orange in color, o# are "ecoming

dehdrated. It mean! the Yidne! are QorYing hardto get rid of to%in! in the "od in &er concentrated #rine. 2hat i! Qh#rine "ecome! darYer in color. DarY color#rine i! a good !ign of dehdration.H1/E0 F1R CURIN ALREADO E02ABLI0HED DI0EA0EShat Qe di!c#!!ed a"o&e Qa! directed at di!ea!e $re&ention. A!cientic and re!earched o$inion, "a!ed on clinical

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o"!er&ation!, and a li!t of di!ea!e! that !eem to ari!e from thee!ta"li!hment of chronic dehdration Qere !hared

Con #!ted.2he aim Qa! to arm o# for f#t#re $re&ention of di!ea!e.HoQe&er, o# might alread "e !#[ering from thead&er!e e[ect! of dehdration and Qi!h to re&er!e the tide of e&ent!that ha&e alread taYen $lace. Let #! ho$e o#ha&e not reached an irre&er!i"le !it#ation and !ome re&er!al of thedi!ea!e $roce!! can "e ho$ed for. /or !#$#e!to,nothing can "e $romi!ed. All Qe can do i! ho$e a correction $atternco#ld e!ta"li!h.Do not forget that at each $ha!e of life, o#r "od i! the $rod#ct of atime*o$erated !erie! of chemical interaction!.Armed Qith correct YnoQledge, it might "e $o!!i"le to re&er!e !ome

reaction!, "#t not all. Fir!t and foremo!t, do notimagine o# co#ld re&er!e the !it#ation if o# noQ 7droQn7 o#r!elf inQater. No e! a!+2he cell! of the "od are liYe!$onge! it taYe! !ome time "efore the "ecome "etter hdrated. Al!odo not forget that !ome of them maYe theirmem"rane! le!! $ermi!!i&e of Qater di[#!ionZin or o#t. 2he r!t $lacethat Qill !hoQ !ign! of "eing 7o&er*Qatered7Qill "e the l#ng! if o#r Yidne! do not lter the e%ce!! Qater. If o#rYidne! are not damaged a! a re!#lt of thelong*!tanding and e%$anding dehdration that the lo!! of thir!t!en!ation Qill a#tomaticall force on the "od, then

o# can feel !afe and drinY the !$ecied amo#nt.If o#r Yidne! ha&e al!o !#[ered from ha&ing to concentrate and $a!!the 7to%ic7 chemical! that Yee$ "#ilding #$Qithin the "od in long*end#red and increa!ing dehdration, then o#ha&e to "e &er ca#tio#!. B noQ, o# m#!tal!o "e #nder medication and $rofe!!ional !#$er&i!ion. Oo# cannot j#!tc#t o#r medication and "egin drinYingQater in $lace of the!e 7chemical mani$#lator! of the "od chemi!tr.7 Oo# !ho#ld for a feQ da! a!!e!! e%actl the(#antit of Qater o# normall drinY and the amo#nt of #rine o# $a!!.NoQ "egin adding one or tQo gla!!e! of

Qater a da to the amo#nt o# #!#all drinY. Al!o mea!#re the (#antitof #rine o# $a!!. If the amo#nt of #rine o#$a!! "egin! to increa!e, then o# can al!o increa!e the Qater o# taYe.If o# are on di#retic!, remem"er that Qateri! the "e!t nat#ral di#retic if the Yidne! f#nction normall. In mo$inion, it i! ignorance*"a!ed 7!cience7 to$re!cri"e the intaYe of di#retic! in $lace of increa!ing Qater intaYe if theYidne! of a $atient are ca$a"le of

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$rod#cing #rine. 2he &og#e in medical $ractice ha! "ecome the !$ontaneo#! and

indi!criminate #!e of di#retic!, calci#m "locYer!,"eta "locYer!, and anti*chole!terol medication! in the t$e of $atient!e%em$lied " Mr. Fo%. 6/or (#' !im$lemente"eca#!e the 7!cience of medicine7 ha! e%$anded on a ho$ele!!lerroneo#! $aradigm. 2he &er fo#ndation of7YnoQledge7 on Qhich medical $ractice of toda i! !taYing it! credi"ilitand licen!e to $ractice i! in error andignorant of Qater meta"oli!m di!t#r"ance a! a $o!!i"le ca#!e of di!ea!eemergence in the h#man "od. 2hat i! hoQ I Qa! ta#ght medicine "efore I di!co&ered m oQnignorance. After reading m "ooY, Dr. J#lian

ShitaYer in hi! 1cto"er 5??= neQ!letter, Health and Healing, that goe!to 99>,>>> $eo$le, Qent $#"lic. He !tated,7In medical !chool I learned that Qater Qa! #nim$ortant to the "od..Sater Qa! inacti&e, !im$l along for the ride,7etc'tera.I am told that he i! ad&i!ing tho!e Qho attend hi! clinic a"o#tchronic dehdration.Oo#r attending$h!ician ha! the !ame "a!i! of Qrong ed#cation a"o#t the h#man "odand it! call! for Qater. Ahora (#e #!ted !a"e"etter, tell him Qhere he ha! gone Qrong in o#r ca!e. A!Y him to!#$er&i!e o#r condition Qhen o# "egin to adj#!to#r dail Qater intaYe and o#r diet. If he or !he i! #naQare of Qhat o#

are talYing a"o#t, !hare the informationo# ha&e ac(#ired on the $ro"lem! a!!ociated Qith long*!tandingchronic dehdration of the "od. Do not gi&e #$ ifo#r re(#e!t i! "r#!hed a!ide on the gro#nd! that o# do not YnoQ Qhato# are talYing a"o#t and he or !he doe!. 2he "od i! #nder a con!tant dri&e to retain !alt to Yee$ Qater in!ide the!!tem. It Qill taYe a grad#al increa!e in#rine to $a!! the e%ce!! !alt o#t. Sater Qill do it if it! intaYe i! increa!ed&er grad#all. Shen #rine formation i!red#ced and !ome edema !QellingG of the leg! and eelid! are $re!ent,increa!ed Qater intaYe !ho#ld "e

$ro$ortionate to increa!ed #rine $rod#ction. A! the $#\ne!! of the ee!and the !Qelling of the anYle! "egin to!hoQ !ign! of "eing red#ced, thenQater intaYe can "e increa!ed. M"a!ic concern i! for the inad&ertent collectionof Qater in the l#ng!. 2hat i! Qh I in!i!t on an acc#rate mea!#rement of #id intaYe and #rine o#t$#t if o# Qi!h tote!t the e[ect of increa!ing o#r dail Qater intaYe and red#cing o#rco[ee and tea intaYe.

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0AL2 FREE DIE2 I0 U22ERLO 02U/ID0alt i! a mo!t e!!ential ingredient of the "od. In their order of 

im$ortance, o%gen, Qater, !alt and $ota!!i#m ranYa! the $rimar element! for the !#r&i&al of the h#man "od. /lin,aro#nd <9 AD, called !alt 7foremo!t amongh#man remedie!.7 He i! right. Oo# !ee, a"o#t ;< $ercent of the !altcontent of the "od i! !tored in the "one! in theform of cr!tal!. It i! !aid that !alt cr!tal! are nat#rall #!ed to maYe"one! hard. 2h#! !alt decienc in the "odal!o co#ld "e re!$on!i"le for the de&elo$ment ofla o!teo$oro!i!.0alt Qill "e taYen o#t of the "one! to maintain it! &italnormal le&el! in the "lood.LoQ !alt intaYe Qill contri"#te to a "#ild*#$ of acidit in !ome cell!. High

acidit in the cell can damage the DNA!tr#ct#re and "e the initiating mechani!m for cancer formation in !omecell!. E%$eriment! ha&e !hoQn that (#ite an#m"er of cancer $atient! !hoQ loQ !alt le&el! in their "od. M ne%t"ooY, ABC of Cancer and De$re!!ion, Qille%$lain in detail a"o#t the im$ortance and the $rimar f#nction of Qaterand !alt in cancer $re&ention.Let me re$eat4 Shen the "od "egin! to collect !alt, it i! doing !o toYee$ Qater in the "od. From thi! 7edema#id,7 it can lter !ome of it! Qater and 7#!h7 it thro#gh the cellmem"rane into !ome of the cell!. It i! the !ame

$rinci$le a! the Qater $#rication $roce!! em$loed in re&er!e o!mo!i!$lant! that man#fact#re drinYing Qater forcomm#nitie! Qitho#t a direct acce!! to fre!h Qater. 2hat i! Qh the ri!ein "lood $re!!#re to "#ild a ltration force i!nece!ario. 2he $reca#tion to Yee$ in mind i! lo!! of !alt from the "od Qhen QaterintaYe i! increa!ed and !alt intaYe i! not.After a feQ da! of taYing !i% or eight or 5> gla!!e! of Qater a da, o#!ho#ld "egin to thinY of adding !ome !alt too#r diet. If o# "egin to feel m#!cle cram$! at night, remem"er o# are"ecoming !alt*decient. Cram$! in

#ne%erci!ed m#!cle! mo!t often mean! !alt !hortage in the "od. Al!o,diine!! and feeling faint might "eindicator! of !alt and Qater !hortage in the "od. If !#ch occa!ion! ari!e,o# !ho#ld al!o "egin to increa!e o#r&itamin! and mineral! intaYeZ$artic#larl if o# are dieting to lo!eQeight or do not eat $ro$erl, incl#ding&egeta"le! and fr#it! for their Qater*!ol#"le &itamin and mineralcontent.

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I ha&e de&elo$ed a r#le of th#m" for dail !alt intaYe. For e&er 5>gla!!e! of Qater a"o#t tQo (#art!G, one !ho#ld

add to the diet a"o#t half of a tea!$oon of !alt $er da. An a&eragetea!$oon can contain !i% gram! of !alt. Half of atea!$oon i! a"o#t three gram! of !alt. 1f co#r!e, one !ho#ld maYe !#rethat the Yidne! are $rod#cing #rine.1therQi!e the "od Qill !Qell #$. If o# !en!eo#r !Yin and anYle! are "eginning to !Qell, do not $anic. Red#ce !altintaYe for a feQ da!, "#t increa!e o#r QaterintaYe #ntil the !Qelling in the leg! di!a$$ear!. Oo# !ho#ld al!o increa!eo#r mo&ement!Ze%erci!e4 m#!cleacti&it Qill draQ the e%ce!! #id into the "lood circ#lation and !ome !alti! then lo!t in $er!$iration and #rine. hacer

not !it or !tand in one, $o!ition too long.Carrot! for their "eta*carotene contentG are an e!!ential dietarre(#irement. Beta*carotene i! a $rec#r!or for&itamin A and a"!ol#tel e!!ential for li&er meta"oli!m, a$art from it!need " the ee!. 0ome orange j#ice for it!$ota!!i#m content !ho#ld al!o "e added to the #id intaYe of the"od./lea!e remem"er, more i! not "etter. dema!iadom#ch orange j#ice Qill ca#!e $ro"lem! of it! oQn. If the "od i!o&erloaded Qith $ota!!i#m, hi!tamine $rod#ction inthe "od Qill increa!e.I ha&e hel$ed $eo$le get rid of long*!tandinga!thma attacY! " a !im$le ad&ice. Ello! eran

a!Yed to limit their orange j#ice intaYe to one, at mo!t, tQo gla!!e! adaZof co#r!e re$lacing the re!t of the dail j#ice intaYe " Qater.At thi! !tage in the "ooY, I Qo#ld liYe to inform o# that a &a!t majoritof &er fre(#entl #!ed medication! are eitherdirectl or indirectl !trong antihi!tamine!. 2he !tronge!t &ariet are#!ed in the di!ci$line of $!chiatr and for$atient! Qith de$re!!ion. Man of the antide$re!!ant dr#g! on themarYet are antihi!tamine!Z!o m#ch !o that!ome ga!troenterologi!t! are #!ing the!e dr#g! for the treatment of #lcer $atient! "eca#!e the are chea$er.

 2here are man of them on the marYet and, "eca#!e of com$etition,their $rice! are loQer than the traditional H"locYing agent! that ha&e cornered the marYet. 2hi! information i! gi&en to indicate that the $harmace#tical ind#!tra$$reciate! the !ignicance of hi!tamineacti&it in the h#man "od. 2he are not here to inform #! of the role of hi!tamine in Qater reg#lation of the "od

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the are "#!ine!! enter$ri!e! intere!ted in marYeting their $rod#ct!. 2hene%t time o#r $h!ician $re!cri"e! a

medication for o#, a!Y if it ha! an anti*hi!tamine acti&it. 2heantihi!tamine medication! mil !trongl a[ect theimm#ne !!tem! of the "od at the le&el of the "one marroQ. 2HE HEAL2H CARE 0O02EM AND 1UR RE0/1N0IBILI2IE0If o# ha&e !#[ered "eca#!e of the a$$lication of 7medical ignorance7 too#r "odT! earlier call! for Qater, it"ecome! the re!$on!i"ilit of o#r attending doctor to !#$er&i!e o#rret#rn to health " tailing o[ the #!e ofchemical! for the treatment of chronic dehdration in o#r "od. Oo#!ho#ld maYe !#re o#r doctor "ecome! aQareof the information on Qater meta"oli!m, and o#r "odT! other call

!ignal! for Qater, Qhen dehdration "egin! toalter the "od $h!iolog.Oo#r doctor i! re!$on!i"le to o# and, a! o#r$h!ician, he need! to "ecome informed. loi! o#r re!$on!i"ilit to hel$ o#r doctor "ecome aQare of the $aradigm!hift. It i! noQ o#r re!$on!i"ilit to hel$change the health care !!tem to QorY for o# and not the commercialand $olitical aim! of it! admini!trator!.It ma "ecome nece!!ar to $a!! legi!lation to e%cl#de dehdration a! aca#!ati&e factor in the $rod#ction ofdi!ea!e condition! "efore an $harmace#tical or in&a!i&e $roced#re! are#ndertaYen. 2he e&al#ation of dr#g! for

#ltimate #!e in treatment $roced#re! !ho#ld "e carried o#t onl after$atient! are f#ll hdrated and !e&eral da!ha&e ela$!ed "efore !tarting the te!t. After all, the Qater #!ed in taYinga $ill i! immediatel more e[ecti&e in adehdrated $er!on than the chemical com$o!ition of the $ill I ha&ee%$lained that the 7$lace"o7 e[ect !een in dr#gtrial! i! mo!t $ro"a"l the re!#lt of !ome correction for the #nrecognieddehdration a! a contri"#ting factor indi!ea!e $rod#ction. Oo# are noQ in 7the arena.7 Oo# !ho#ld #!e o#rYnoQledge for the "enet of manYind and trto "ring a"o#t the $aradigm !hift on Qater meta"oli!m of the "od into

the e&erda $ractice of medicine.C102 0AIN0 21 2HE NA2I1N 2he $aradigm change in medicine, a! it ha! "een e%$o!ed, Qhen f#llado$ted and $racticed, Qill !a&e a large$ortion of the &a!t and #nnece!!ar health care co!t! and e%$endit#re" !ociet.H$erten!ion and it! a!!ociated cardio&a!c#lar di!order! are co!ting thi!nation o&er 5>> "illion dollar! a ear. e!$alda

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$ain tran!late! into an :>*"illion*dollar*a*ear lo!! to !ociet.Rhe#matoid joint di!ea!e i! a[ecting ;> million elderl

$eo$le and i! co!ting thi! nation man ten! of "illion! of dollar! ann#allZto name "#t a feQ heading!. de lo!a$$ro%imatel :9> "illion dollar! health care co!t! in 5??; alone, a"o#t9> to @> $ercent are mo!t $ro"a"l inc#rreda! a re!#lt of $rimiti&e error! a"o#t chronic dehdration and thea!!ociated !ignal !!tem! that !ho#ld "e tran!lateda! the main thir!t indicator! of the "od.A !im$le correction of thi! long*!tanding !cientic mi!taYe can re&er!ethe "#dget decit of thi! nation. En c#al(#ier ca!o,the $aradigm !hift Qill al!o $rod#ce a m#ch healthier !ociet. It i!e!timated that the r#naQa co!t of health care in

thi! !ociet Qill reach 5.@ trillion dollar! " the ear ;>>> and Qillincrea!e to ;: $ercent of the ro!! National/rod#ct " the ear ;>5>. E&en Qith !#ch ri!e in e%$endit#re, no feQerthan 9> million $eo$le co#ld not a[ord to $athe ri!ing co!t! of health in!#rance and Qill "e de$ri&ed of ade(#ateco&erage. 2he $aradigm !hift Qill re&er!e thi!7no !ol#tion in !ight7 health care co!t !$iraling trend.I in&ite o# to !hare the information in thi! "ooY Qith o#r relati&e! andfriend!.Oo# Qill "e doing them a fa&or. $orre!$onding $o!iti&el to thi! in&itation, o# Qill "e at the !ame timehel$ing thi! nation red#ce it! health care co!t!

" at lea!t @> $ercent. It i! criminal that at the end of ;>th Cent#r,h#man thir!t for Qater i! !till "eing treated Qith!loQ $oi!on!. 2engo #na $etición.If the information in thi! "ooY hel$! o#, $lea!e Qriteme a note a"o#t o#r $artic#lar condition andhoQ increa!ed Qater intaYe ha! hel$ed o#. Se need to doc#ment a!m#ch information on chronic dehdration a!e! $o!i"le.It i! a &er o#ng !cience.It need! the in$#t of all Qho te!t theinformation.Oo#r $artici$ation Qill !a&eother! Qith !imilar $ro"lem! from #nnece!!ar !#[ering that localdehdration co#ld $rod#ce Qitho#t "eing !o

identicado.LiYe the letter! $rinted in thi! "ooY, o#r in$#t canill#minate the $ath of other! in the f#t#re.FINALMEN2EBa!ed on the a"o&e $h!iological a$$roach to di!ea!e emergence, it i!noQ $o!!i"le to taYe a re!ol#te !tand to endmajor dehdration*$rod#ced di!ea!e! on earth Qithin tQo decade!. 2he$#"lic m#!t demand the $aradigm change

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and ado$t the neQ $aradigm them!el&e! to free manYind from all the7!cientic7 mi!conce$tion! $er$et#ated for

$rot*moti&ated "#!ine!! e%$an!ion Qithin the health care !!tem. Mcolleag#e! in the medical $rofe!!ion m#!t!imilarl !to$ treating the !ignal! of dehdration of the "od " theindi!criminate #!e of $harmace#tical $rod#ct! or$rocedimiento! in&a!i&o!.In 5??>, the $re!ident and all the "oard mem"er! of the AmericanMedical A!!ociation Qere !ent an in&itation "the Fo#ndation for the 0im$le in Medicine to !hare the $ro&idedinformation of the $aradigm !hift on Qatermeta"oli!m of the "od Qith their acti&e medical colleag#e!. 2hi! letterof in&itation Qa! !#"!e(#entl $#"li!hed in

the 5??5 i!!#e of 0cience In Medicine 0im$lied. It i! al!o $re!ented inthe folloQing $age! Qith !#"!e(#entcorre!$ondence! Qith AMA. Oo# are noQ "eing informed of !ome of theaction! taYen to "ring m nding! a"o#tchronic dehdration to o# thro#gh the mem"er! of AMA. 2hi! i! an in&itation that o# m#!t forcef#ll e%tend to o#r $er!onaldoctor and admini!trator! of the health care!!tem! in o#r !ociet. More than eno#gh !cientic information todemand the nece!!ar change in the $re!ent!tr#ct#re of the health care !!tem i! noQ a&aila"le. /lea!e do not "eindi[erent to the $ain and !#[ering of other!.

 2aYe a re!ol#te !tand to !to$ the $re!ent health care !ting again!t tho!eQho do not et YnoQ that chronic