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    The Power of Prevention:

    Rhymes to Remember 

    Florida State University

    College of MedicineFebruary 10, 2011

    Steven H. Woolf, MD, MPH, FACPM

    Department of Family Medicine, Centeron Human Needs

    Virginia Commonwealth University

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    Categories of Prevention

    Primary prevention

    Secondary prevention

    Tertiary prevention

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    Clinical Preventive Services

    Screening tests

    Counseling interventions

    Immunizations

    Chemoprophylaxis

    Community Preventive Services

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    Leading Causes of Death

    Tobacco use

    Diet

    Physical inactivity

    Problem drinking

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    Social determinantsof health

    Primary prevention Secondary

    preventionTertiary

    prevention

    Determinants of Population Health

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    Role of CliniciansRationale for clinician involvement

    Credibility and imprimatur of adviceIntegration with primary care and medical history

    ImpedimentsBenefits of counseling depend on intensity

    Lack of time, skills, staff, reimbursement to offerintensive counseling and ongoing support

    Practice redesign to offer such services notfeasible in typical US primary care practices

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     A New Decade Dawns

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    Past as Prologue

    "History doesn't repeat itself,but it does rhyme."

    Mark Twain

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    Rhymes: What Hasn’t Changed

    Deaths and injuries from preventable

    causes continue

    Unhealthy behaviors persist

    Many lethal diseases (e.g., lung, ovarian,pancreatic cancer) remain unpreventable

    Too much is wasted on dubious tests and

    scans

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    Rhymes: What Hasn’t Changed

    The argument for evidence-based

    medicine persists

    The need for systematic methods to

    critique evidence persistsGood evidence on effectiveness is sparse

    Experts continue to challenge evidence

     Advocates continue to dismiss harms

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    “This is How Rationing Begins”

    “This is how rationing begins…This is whathe had warned about.”

    Rep. Marsha Blackburn (R-Tenn.)

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    Why not screen?

     Assuming monetary costs are not the

    issue…

    If there is even the slightest possibility ofbenefit, albeit unproved, why shouldn’t

    patients be offered screening and the

    chance to avoid adverse outcomes fromundetected disease?

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    Schwartz et al. JAMA 2004;291(1):71-8.

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    Harms of Screening

    Test procedure

     Anxiety and labeling effects

    False-positive results

    Harms of treatment

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    Elmore et al., 19989762 mammograms over 10 years

    24% = false positives49% cumulative probability over 10 years

    Consequences of false positives

     – 870 outpatient appointments – 539 diagnostic mammograms

     – 186 ultrasound examinations

     – 188 biopsies

    19% probability of biopsy over 10 years

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    Rhymes: What Hasn’t Changed

    The U.S. Preventive Services Task Force

    and the Community Task Force onPreventive Services

     – Philosophy and mission

     – Composition

     – Rules (hierarchy) of evidence

     – Focus on science – Vulnerability to criticism

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    Rhymes: What Hasn’t Changed

    The Mammogram Wars

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    “Many members of the public were confused by the report.”

    “‘It was a shame that the report was ever published, and Ithink the public ought to ignore the findings,’ said Dr.

    Charles R. Smart, chief of the early detection branch,division of cancer prevention and control, of the NationalCancer Institute in Bethesda, Md.”

    New York Times, May 4, 1987

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    New mammography questions raised

    Mammography Review Shatters the Status Quo

    Doubts About Its Value Alarm Many

    Dispute Builds Over Value of

    Mammography

    Circling the Mammography

    Wagons

    Expert Panel Cites Doubts On Mammogram's

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    Rhymes: What Hasn’t Changed

    Special interests,

    profit motivesGovernment intrusion

    The need to insulate

    science from politics

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    Rhymes: What Hasn’t Changed

    Disparities, inequity, “reverse targeting”

    Misplaced priorities

    2%

    98%

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    International Symposium on Preventive Services in Primary Care, Hotel l’Esterel,

    Quebec, October 4-7, 1987

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    What Has Changed in 25

    Years?

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    What Has Changed?

     Acceptance of prevention: from fringe idea

    to national stageRecession, health care reform, and

    leverage of prevention

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    What Has Changed?

    The evidence base for prevention

     Accepted core of effective preventive services – Screening tests

     – Clinical expectation to address modifiable risk factors

     – Effective public health and population-basedstrategies

    Name recognition of USPSTF and Community

    Task ForcesDangers to independent scientific analysis

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    What Has Changed?

     Attempts at prioritization

    Understanding of implementationchallenges

    QALY S d if Utili ti W I d

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    QALYs Saved if Utilization Were Increased

    Above Current LevelsService % Currently Receiving QALYs saved if use

    increased to 90%

    Tobacco Cessation Counseling 35% 1.3 million

    Colorectal Cancer Screening 25% 340,000

    Influenza immunization 36% and 65% 110,000

    Breast cancer screening 68% 91,000

    Cervical cancer screening 79% 29,000

    Chlamydia Screening 40% 19,000

    Pneumococcal immunization 56% 16,000

    Cholesterol screening 87% 12,000

    Hypertension screening 90% 0

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    What Has Changed?

    The “information age”: the good and bad

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    What Has Changed?What’s in:

     – New screeningtechnologies

     – Genomics and

    personalized medicine

    What’s out:

     – Hormone replacement

    therapy

     – “Preventative”

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     A New Way of Thinking About

    Preventive Medicine

    It’s not aboutcolonoscopies and

    mammograms

    It’s not about

    “exerciseprescriptions”

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    Beyond the Clinical Setting

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    Socioecological Model

    From: The Future of the Public's Health (IOM 2003).

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    The Obesity PlayersCommunity

    organizations

    Health care

    Public health

    Worksites

    SchoolsMedia and advertising

    Retailers

    Built environment

    Supermarkets

    Restaurants

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    The Problem of Silos

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    Clinical-Community Collaboration

    Clinical settingsPublic health and

    community

    organizations

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    Source: Davis RM. Am J Prev Med 2005;29:154-7.

    The Medicine-Public Health Divide

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    The do campaign – workplace signs

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    Sample ads – in stores, billboards, etc.

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    Physical environment influences behavior

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    Social Determinants of Health

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    Source: VCU Center on Human Needs: http://www.societaldistress.org/Content.aspx?ID=79

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    Health in All PoliciesEducation

    JobsIncome

    Environment

    Transportation

    Housing

     Agriculture

    ImmigrationLand use and zoning

    Neighborhood

    developmentCrime and safety

    Communication

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    Communication

    Opportunities and Expectations A rapt audience for prevention

     – Elected officials, CEOs, insurers – Health care professionals

     – Public health and community organizations

     – The public, patients

     – Media

     – Commercial interestsComplex messages to deliver 

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    Complex Messages To Deliver Screening can save lives, but harms can

    outweigh benefitsObesity is a dire public health problem, but

    evidence is lacking for physicians to counsel

     A child can be harmed by vaccines, but childrenin general benefit from herd immunity

    Preventing diseases doesn’t necessarily save

    money, but it offers good economic value

    Communication:

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    Communication:

    Science vs. AgendasPatients and the public want…

     – More, not less (“rationing”) – Tests, not “talk”

     – Certainty: what to do and not do, and why

     – No risk, and to ignore risks

     – Simple messages: the complex as “sound

    bites”

    Communication:

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    Communication:

    Science vs. Agendas

    Commercial interests

     – Profits & power  – Countermarketing

    Elected officials

     – Votes

     – Campaigndonations

     – Diseases ofpersonal interest

    Government officials,

    agency heads – Inertia

     – Bureaucracy

    Media – 24-hour news

    cycle, ratings,

    inpatient audience