1. tecnologÍa / tecnovigilancia. 3. alertas ecri ......trabajo sobre desinfectantes y antisépticos...

1. TECNOLOGÍA / TECNOVIGILANCIA.

2. NORMATIVA/REGULACIÓN /RECOMENDACIONES.

3. ALERTAS ECRI.

4. MICROORGANISMOS MULTIRRESISTENTES.

5. CASOS PRÁCTICOS.

TECNOLOGÍA

Febrero 2017

8 Responsabilizar al personal sanitario de la limpieza del material sanitario (fonendoscopios, linternas…) y no sanitario que utilizan de forma habitual (teclado de ordenadores, teléfonos fijos y móviles, llaves, etc).

13J. M. Arévalo, J. L. Arribas, M.' J. Hernández, M. Lizán. Coordinador: R. Herruzo Grupo de

trabajo sobre Desinfectantes y Antisépticos (SEMPSPH). Guía de utilización de antisépticos

NORMATIVA

REGULACIÓN

RECOMENDACIONES

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Article 2 Definitions

1. For the purposes of this Regulation, the following definitions shall apply:

Definitions related to devices:

(1) ‘medical device’ means any instrument, apparatus, appliance, software, implant, reagent,

material or other article, intended by the manufacturer to be used, alone or in combination,

for human beings for one or more of the specific medical purposes of:

– diagnosis, prevention, monitoring, prediction, prognosis, treatment or alleviation of

disease;

– diagnosis, monitoring, treatment, alleviation of or compensation for an injury or disability,

– investigation, replacement or modification of the anatomy or of a physiological or

pathological process or state,

– providing information by means of in vitro examination of specimens derived from the

human body, including organ, blood and tissue donations,

and which does not achieve its principal intended action by pharmacological, immunological

or metabolic means, in or on the human body, but which may be assisted in its function by

such means.

Products specifically intended for the cleaning, disinfection or sterilisation of medical devices

and devices for the purpose of control or support of conception shall be considered medical

devices.

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ALERTAS ECRI

2017

MMR

-Diagnóstico microbiológico-Aislamiento-Infección

LLEGAMOS TARDE

-Diagnóstico microbiológico-Aislamiento-Infección

LLEGAMOS TARDE

Davies J, Davies D. Origins and evolution of antibiotic resistance. Reflections on resistance. Microbiol Mol Biol Rev. 2010; 74(3):417-33.

Lee C. The Antibiotic Resistance Crisis. Part 1: Causes and Threats. Pharmacy and Therapeutics. 2015; 40(4): 277–283.

Maryn Mkennahttps://medium.com/@fernnews/imagining-the-post-antibiotics-future-892b57499e77

O’Neill J. Antimicrobial Resistance: Tackling a crisis for the health and wealth of nations. London: The Review of Antimicrobial Resistance; 2014.

O’Neill J. Tackling drug-resistant infections globally: Final report and recommendations. London: The Review on Antimicrobial Resistance; 2016.

The World Bank. Drug-Resistant Infections: A Threat to Our Economic Future (Discussion Draft). International Bank for Reconstruction and Development. Washington: The World Bank; 2016.

Incremento en el número de personas en situación de pobreza según dos escenarios (Low-AMR: bajas RAM y High-AMR: altas RAM) y en función de países de altos ingresos (anarajando) y de bajos ingresos (azul).

Global Union for Antibiotics Research and Development. Follow-up report for the German GUARD initiative: Breaking through the Wall. A Call for Concerted Action on Antibiotics Research and Development. Boston: The Boston Consulting Group; 2017.

2001 2011 2015 2016 2017

Global Union for Antibiotics Research and Development. Follow-up report for the German GUARD initiative: Breaking through the Wall. A Call for Concerted Action on Antibiotics Research and Development. Boston: The Boston Consulting Group; 2017.

2001 2011 2015 2016 2017

AcinetobacerAcinetobacer baumanniibaumannii, resistente a carbapenemes

Pseudomonas Pseudomonas aeruginosaaeruginosa, resistente a carbapenemes

EnterobacteriaceaeEnterobacteriaceae**, resistentes a carbapenemes y a cefalosporinas de tercera generación.

Tacconelli E, N. Magrini. Global Priority List of Antibiotic-Resistant Bacteria to Guide Research, Discovery andDevelopment of New Antibiotics. Ginebra: Organización Mundial de la Salud; 2017.

Marston HD, Dixon DM, Knisely M, Palmore TN, Fauci AS. Antimicrobial Resistance. JAMA. 2016;316(11):1193-204.

Tafur JD, Torres JA, Villegas MV. Mecanismos de resistencia a los antibióticos en bacterias Gram negativas. Asociación Colombiana de Infectología. CIDEIM. 2008; 12(3):217-226.

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Lee CR, Lee JH, Park KS, Kim YB, Jeong BC, Lee SH. Global Dissemination of Carbapenemase-producing Klebsiellapneumoniae: Epidemiology, Genetic Context, Treatment Options, and Detection Methods. Front. Microbiol. 2016;7:895.

β-lactamasasCARBAPENEMASAS

Xavier BB, Lammens C, Ruhal R, Kumar-Singh S, Butaye P, Goossens H, Malhotra-Kumar S. Identification of a novel plasmid-mediated colistin-resistance gene, mcr-2, in Escherichia coli, Belgium, June 2016. Euro Surveill. 2016;21(27):pii=30280.

Liu YY, et al. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study. Lancet Infect Dis 2016;16(2):161-168.Resistencia a

POLIMIXINAS

Marston HD, Dixon DM, Knisely M, Palmore TN, Fauci AS. Antimicrobial Resistance. JAMA. 2016;316(11):1193-204.

Fuente: Organización Mundial del Turismo

Van der Bij AK, Pitout JD. The role of international travel in the worldwide spreadofmultiresistant Enterobacteriaceae. J Antimicrob Chemother 2012; 67: 2090–2100

Van der Bij AK, Pitout JD. The role of international travel in the worldwide spreadofmultiresistant Enterobacteriaceae. J Antimicrob Chemother 2012; 67: 2090–2100

Nordmann P, Naas T, Poirel L. Global spread of carbapenemase-producingEnterobacteriaceae. Emerg Infect Dis. 2011;17:1791-8.

Lee CR, Lee JH, Park KS, Kim YB, Jeong BC, Lee SH. Global Dissemination of Carbapenemase-producingKlebsiella pneumoniae: Epidemiology, Genetic Context, Treatment Options, and Detection Methods. Front. Microbiol. 2016;7:895.

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IV Encuentro Pirasoa, 2016. Presentación Mª Dolores Rojo Martín.Servicio Microbiología, Hospital Universitario Virgen de las nieves. Granada

ALGUNOS CASOS PRÁCTICOS

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